| Full name: tetratricopeptide repeat domain 17 | Alias Symbol: FLJ10890 | ||
| Type: protein-coding gene | Cytoband: 11p12-p11.2 | ||
| Entrez ID: 55761 | HGNC ID: HGNC:25596 | Ensembl Gene: ENSG00000052841 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC17 | 55761 | 224849_at | -0.0990 | 0.8195 | |
| GSE20347 | TTC17 | 55761 | 218972_at | -0.0568 | 0.7845 | |
| GSE23400 | TTC17 | 55761 | 218972_at | 0.1389 | 0.0252 | |
| GSE26886 | TTC17 | 55761 | 218972_at | 0.0683 | 0.8106 | |
| GSE29001 | TTC17 | 55761 | 218972_at | 0.0144 | 0.9435 | |
| GSE38129 | TTC17 | 55761 | 218972_at | 0.1192 | 0.4800 | |
| GSE45670 | TTC17 | 55761 | 224849_at | -0.2922 | 0.0711 | |
| GSE53622 | TTC17 | 55761 | 135160 | 0.0457 | 0.5320 | |
| GSE53624 | TTC17 | 55761 | 135160 | 0.0940 | 0.0312 | |
| GSE63941 | TTC17 | 55761 | 218972_at | 0.8147 | 0.1845 | |
| GSE77861 | TTC17 | 55761 | 224849_at | 0.1453 | 0.4780 | |
| GSE97050 | TTC17 | 55761 | A_23_P414899 | -0.1520 | 0.4920 | |
| SRP007169 | TTC17 | 55761 | RNAseq | 0.0021 | 0.9947 | |
| SRP008496 | TTC17 | 55761 | RNAseq | 0.1807 | 0.2624 | |
| SRP064894 | TTC17 | 55761 | RNAseq | 0.0067 | 0.9682 | |
| SRP133303 | TTC17 | 55761 | RNAseq | 0.2002 | 0.3109 | |
| SRP159526 | TTC17 | 55761 | RNAseq | -0.2416 | 0.1785 | |
| SRP193095 | TTC17 | 55761 | RNAseq | -0.1104 | 0.2295 | |
| SRP219564 | TTC17 | 55761 | RNAseq | 0.1428 | 0.6402 | |
| TCGA | TTC17 | 55761 | RNAseq | -0.1382 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC17 | 55761 | 2 | 7 | 21 | |
| GSE20123 | TTC17 | 55761 | 2 | 6 | 22 | |
| GSE43470 | TTC17 | 55761 | 3 | 5 | 35 | |
| GSE46452 | TTC17 | 55761 | 8 | 5 | 46 | |
| GSE47630 | TTC17 | 55761 | 3 | 9 | 28 | |
| GSE54993 | TTC17 | 55761 | 3 | 0 | 67 | |
| GSE54994 | TTC17 | 55761 | 2 | 10 | 41 | |
| GSE60625 | TTC17 | 55761 | 0 | 0 | 11 | |
| GSE74703 | TTC17 | 55761 | 2 | 3 | 31 | |
| GSE74704 | TTC17 | 55761 | 2 | 5 | 13 | |
| TCGA | TTC17 | 55761 | 13 | 20 | 63 |
Total number of gains: 40; Total number of losses: 70; Total Number of normals: 378.
Somatic mutations of TTC17:
Generating mutation plots.
Highly correlated genes for TTC17:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC17 | FAM120B | 0.816388 | 3 | 0 | 3 |
| TTC17 | GABPB2 | 0.775228 | 3 | 0 | 3 |
| TTC17 | TRIM56 | 0.773781 | 3 | 0 | 3 |
| TTC17 | STAMBPL1 | 0.756175 | 3 | 0 | 3 |
| TTC17 | MAN1A2 | 0.753905 | 3 | 0 | 3 |
| TTC17 | NCBP2 | 0.752493 | 3 | 0 | 3 |
| TTC17 | ZNF76 | 0.75226 | 3 | 0 | 3 |
| TTC17 | ZKSCAN1 | 0.74912 | 3 | 0 | 3 |
| TTC17 | TSPAN3 | 0.748745 | 3 | 0 | 3 |
| TTC17 | ZNF641 | 0.740229 | 4 | 0 | 3 |
| TTC17 | KIAA2026 | 0.739517 | 3 | 0 | 3 |
| TTC17 | SRSF6 | 0.730802 | 3 | 0 | 3 |
| TTC17 | ZNF44 | 0.728326 | 3 | 0 | 3 |
| TTC17 | PPM1K | 0.724535 | 3 | 0 | 3 |
| TTC17 | ERAP1 | 0.723721 | 3 | 0 | 3 |
| TTC17 | PPM1M | 0.719267 | 3 | 0 | 3 |
| TTC17 | PEX3 | 0.717902 | 3 | 0 | 3 |
| TTC17 | TM7SF3 | 0.715403 | 4 | 0 | 3 |
| TTC17 | CLK2 | 0.714684 | 4 | 0 | 4 |
| TTC17 | CLEC16A | 0.7145 | 3 | 0 | 3 |
For details and further investigation, click here
