| Full name: M-phase phosphoprotein 8 | Alias Symbol: mpp8|HSMPP8 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 54737 | HGNC ID: HGNC:29810 | Ensembl Gene: ENSG00000196199 | OMIM ID: 611626 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MPHOSPH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPHOSPH8 | 54737 | 225041_at | -0.5633 | 0.5043 | |
| GSE20347 | MPHOSPH8 | 54737 | 221771_s_at | -0.8324 | 0.0000 | |
| GSE23400 | MPHOSPH8 | 54737 | 221771_s_at | -0.4226 | 0.0000 | |
| GSE26886 | MPHOSPH8 | 54737 | 225041_at | 0.1926 | 0.6799 | |
| GSE29001 | MPHOSPH8 | 54737 | 221771_s_at | -0.6664 | 0.0285 | |
| GSE38129 | MPHOSPH8 | 54737 | 221771_s_at | -0.9037 | 0.0000 | |
| GSE45670 | MPHOSPH8 | 54737 | 225041_at | -0.1107 | 0.4554 | |
| GSE53622 | MPHOSPH8 | 54737 | 55221 | -0.3422 | 0.0000 | |
| GSE53624 | MPHOSPH8 | 54737 | 55221 | -0.4420 | 0.0000 | |
| GSE63941 | MPHOSPH8 | 54737 | 227026_at | -0.2520 | 0.5525 | |
| GSE77861 | MPHOSPH8 | 54737 | 225041_at | 0.3253 | 0.3287 | |
| GSE97050 | MPHOSPH8 | 54737 | A_23_P204967 | -0.4585 | 0.1325 | |
| SRP007169 | MPHOSPH8 | 54737 | RNAseq | 0.6357 | 0.1717 | |
| SRP008496 | MPHOSPH8 | 54737 | RNAseq | 0.6806 | 0.0446 | |
| SRP064894 | MPHOSPH8 | 54737 | RNAseq | 0.0381 | 0.8620 | |
| SRP133303 | MPHOSPH8 | 54737 | RNAseq | -0.3751 | 0.0075 | |
| SRP159526 | MPHOSPH8 | 54737 | RNAseq | -0.3164 | 0.1030 | |
| SRP193095 | MPHOSPH8 | 54737 | RNAseq | -0.1863 | 0.1442 | |
| SRP219564 | MPHOSPH8 | 54737 | RNAseq | -0.3397 | 0.3401 | |
| TCGA | MPHOSPH8 | 54737 | RNAseq | -0.2873 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPHOSPH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPHOSPH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPHOSPH8 | 54737 | 1 | 16 | 13 | |
| GSE20123 | MPHOSPH8 | 54737 | 1 | 15 | 14 | |
| GSE43470 | MPHOSPH8 | 54737 | 1 | 13 | 29 | |
| GSE46452 | MPHOSPH8 | 54737 | 0 | 33 | 26 | |
| GSE47630 | MPHOSPH8 | 54737 | 3 | 26 | 11 | |
| GSE54993 | MPHOSPH8 | 54737 | 11 | 2 | 57 | |
| GSE54994 | MPHOSPH8 | 54737 | 2 | 12 | 39 | |
| GSE60625 | MPHOSPH8 | 54737 | 0 | 3 | 8 | |
| GSE74703 | MPHOSPH8 | 54737 | 1 | 10 | 25 | |
| GSE74704 | MPHOSPH8 | 54737 | 0 | 13 | 7 | |
| TCGA | MPHOSPH8 | 54737 | 7 | 43 | 46 |
Total number of gains: 27; Total number of losses: 186; Total Number of normals: 275.
Somatic mutations of MPHOSPH8:
Generating mutation plots.
Highly correlated genes for MPHOSPH8:
Showing top 20/568 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPHOSPH8 | RSF1 | 0.748098 | 4 | 0 | 4 |
| MPHOSPH8 | ZSCAN29 | 0.739255 | 3 | 0 | 3 |
| MPHOSPH8 | TMEM159 | 0.735358 | 4 | 0 | 4 |
| MPHOSPH8 | RYBP | 0.715894 | 4 | 0 | 3 |
| MPHOSPH8 | NUDCD3 | 0.713852 | 3 | 0 | 3 |
| MPHOSPH8 | ZBTB7A | 0.710007 | 4 | 0 | 3 |
| MPHOSPH8 | ZNF570 | 0.70339 | 4 | 0 | 4 |
| MPHOSPH8 | TTF1 | 0.699055 | 4 | 0 | 3 |
| MPHOSPH8 | GBA2 | 0.693693 | 3 | 0 | 3 |
| MPHOSPH8 | DDX42 | 0.686066 | 4 | 0 | 3 |
| MPHOSPH8 | FKBP8 | 0.684729 | 4 | 0 | 3 |
| MPHOSPH8 | RIMKLB | 0.679116 | 3 | 0 | 3 |
| MPHOSPH8 | N4BP2L2 | 0.673659 | 8 | 0 | 7 |
| MPHOSPH8 | CDADC1 | 0.672457 | 4 | 0 | 3 |
| MPHOSPH8 | ZNF383 | 0.669141 | 5 | 0 | 4 |
| MPHOSPH8 | RUFY3 | 0.668709 | 7 | 0 | 6 |
| MPHOSPH8 | ABCA8 | 0.668624 | 5 | 0 | 4 |
| MPHOSPH8 | WASL | 0.668428 | 3 | 0 | 3 |
| MPHOSPH8 | ADH1C | 0.667506 | 3 | 0 | 3 |
| MPHOSPH8 | RREB1 | 0.667337 | 4 | 0 | 4 |
For details and further investigation, click here
