| Full name: defective in cullin neddylation 1 domain containing 4 | Alias Symbol: KIAA0276 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 23142 | HGNC ID: HGNC:28998 | Ensembl Gene: ENSG00000109184 | OMIM ID: 612977 |
| Drug and gene relationship at DGIdb | |||
Expression of DCUN1D4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCUN1D4 | 23142 | 212855_at | -0.0479 | 0.9671 | |
| GSE20347 | DCUN1D4 | 23142 | 212855_at | -0.5193 | 0.0037 | |
| GSE23400 | DCUN1D4 | 23142 | 212851_at | 0.0674 | 0.5319 | |
| GSE26886 | DCUN1D4 | 23142 | 212855_at | -0.6031 | 0.0604 | |
| GSE29001 | DCUN1D4 | 23142 | 212855_at | 0.0204 | 0.9532 | |
| GSE38129 | DCUN1D4 | 23142 | 212855_at | -0.5556 | 0.0023 | |
| GSE45670 | DCUN1D4 | 23142 | 212855_at | -0.8171 | 0.0005 | |
| GSE53622 | DCUN1D4 | 23142 | 107320 | -0.4274 | 0.0000 | |
| GSE53624 | DCUN1D4 | 23142 | 107320 | -0.4157 | 0.0000 | |
| GSE63941 | DCUN1D4 | 23142 | 212855_at | -1.2647 | 0.1028 | |
| GSE77861 | DCUN1D4 | 23142 | 212855_at | -0.3177 | 0.1801 | |
| GSE97050 | DCUN1D4 | 23142 | A_32_P43812 | -0.6710 | 0.1313 | |
| SRP007169 | DCUN1D4 | 23142 | RNAseq | -0.1265 | 0.7636 | |
| SRP008496 | DCUN1D4 | 23142 | RNAseq | 0.0242 | 0.9237 | |
| SRP064894 | DCUN1D4 | 23142 | RNAseq | 0.1812 | 0.3072 | |
| SRP133303 | DCUN1D4 | 23142 | RNAseq | -0.0031 | 0.9903 | |
| SRP159526 | DCUN1D4 | 23142 | RNAseq | -0.6926 | 0.0031 | |
| SRP193095 | DCUN1D4 | 23142 | RNAseq | -0.3302 | 0.0068 | |
| SRP219564 | DCUN1D4 | 23142 | RNAseq | -0.3109 | 0.3879 | |
| TCGA | DCUN1D4 | 23142 | RNAseq | -0.2302 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCUN1D4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCUN1D4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCUN1D4 | 23142 | 4 | 11 | 15 | |
| GSE20123 | DCUN1D4 | 23142 | 3 | 11 | 16 | |
| GSE43470 | DCUN1D4 | 23142 | 0 | 14 | 29 | |
| GSE46452 | DCUN1D4 | 23142 | 1 | 36 | 22 | |
| GSE47630 | DCUN1D4 | 23142 | 1 | 18 | 21 | |
| GSE54993 | DCUN1D4 | 23142 | 7 | 0 | 63 | |
| GSE54994 | DCUN1D4 | 23142 | 2 | 10 | 41 | |
| GSE60625 | DCUN1D4 | 23142 | 0 | 0 | 11 | |
| GSE74703 | DCUN1D4 | 23142 | 0 | 12 | 24 | |
| GSE74704 | DCUN1D4 | 23142 | 2 | 6 | 12 | |
| TCGA | DCUN1D4 | 23142 | 17 | 30 | 49 |
Total number of gains: 37; Total number of losses: 148; Total Number of normals: 303.
Somatic mutations of DCUN1D4:
Generating mutation plots.
Highly correlated genes for DCUN1D4:
Showing top 20/889 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCUN1D4 | CDNF | 0.776865 | 3 | 0 | 3 |
| DCUN1D4 | SLC25A30 | 0.747789 | 3 | 0 | 3 |
| DCUN1D4 | POGK | 0.738946 | 3 | 0 | 3 |
| DCUN1D4 | GBA2 | 0.737596 | 3 | 0 | 3 |
| DCUN1D4 | GPBP1 | 0.734363 | 4 | 0 | 4 |
| DCUN1D4 | ACSL1 | 0.725995 | 3 | 0 | 3 |
| DCUN1D4 | RHOJ | 0.72539 | 3 | 0 | 3 |
| DCUN1D4 | BRD8 | 0.718052 | 3 | 0 | 3 |
| DCUN1D4 | FBXL3 | 0.7132 | 5 | 0 | 4 |
| DCUN1D4 | BIVM | 0.710677 | 3 | 0 | 3 |
| DCUN1D4 | TNFSF12 | 0.710009 | 3 | 0 | 3 |
| DCUN1D4 | UTP14C | 0.709565 | 3 | 0 | 3 |
| DCUN1D4 | PRRC1 | 0.70765 | 3 | 0 | 3 |
| DCUN1D4 | TYW3 | 0.707363 | 4 | 0 | 3 |
| DCUN1D4 | LRFN5 | 0.706461 | 3 | 0 | 3 |
| DCUN1D4 | DICER1 | 0.706212 | 3 | 0 | 3 |
| DCUN1D4 | MAP4K3 | 0.704263 | 4 | 0 | 3 |
| DCUN1D4 | GPRASP2 | 0.702403 | 3 | 0 | 3 |
| DCUN1D4 | ZBTB8A | 0.700733 | 4 | 0 | 4 |
| DCUN1D4 | ARFGEF2 | 0.700596 | 5 | 0 | 5 |
For details and further investigation, click here
