| Full name: coiled-coil domain containing 149 | Alias Symbol: DKFZp761B107 | ||
| Type: protein-coding gene | Cytoband: 4p15.2 | ||
| Entrez ID: 91050 | HGNC ID: HGNC:25405 | Ensembl Gene: ENSG00000181982 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC149:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC149 | 91050 | 226141_at | 0.1560 | 0.8755 | |
| GSE26886 | CCDC149 | 91050 | 1553839_at | 0.1504 | 0.3754 | |
| GSE45670 | CCDC149 | 91050 | 1553840_a_at | -0.1172 | 0.3047 | |
| GSE53622 | CCDC149 | 91050 | 76837 | -0.1515 | 0.2220 | |
| GSE53624 | CCDC149 | 91050 | 131055 | -1.9828 | 0.0000 | |
| GSE63941 | CCDC149 | 91050 | 226141_at | -0.7139 | 0.1450 | |
| GSE77861 | CCDC149 | 91050 | 1553839_at | 0.0804 | 0.4786 | |
| GSE97050 | CCDC149 | 91050 | A_23_P419764 | -0.7133 | 0.2304 | |
| SRP007169 | CCDC149 | 91050 | RNAseq | 2.7165 | 0.0069 | |
| SRP064894 | CCDC149 | 91050 | RNAseq | 0.1890 | 0.5252 | |
| SRP133303 | CCDC149 | 91050 | RNAseq | -0.3066 | 0.3352 | |
| SRP159526 | CCDC149 | 91050 | RNAseq | 0.5282 | 0.1417 | |
| SRP193095 | CCDC149 | 91050 | RNAseq | 0.3739 | 0.1468 | |
| SRP219564 | CCDC149 | 91050 | RNAseq | 0.1739 | 0.7938 | |
| TCGA | CCDC149 | 91050 | RNAseq | -0.5945 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CCDC149 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC149:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC149 | 91050 | 0 | 18 | 12 | |
| GSE20123 | CCDC149 | 91050 | 0 | 16 | 14 | |
| GSE43470 | CCDC149 | 91050 | 0 | 15 | 28 | |
| GSE46452 | CCDC149 | 91050 | 1 | 36 | 22 | |
| GSE47630 | CCDC149 | 91050 | 1 | 19 | 20 | |
| GSE54993 | CCDC149 | 91050 | 10 | 0 | 60 | |
| GSE54994 | CCDC149 | 91050 | 5 | 11 | 37 | |
| GSE60625 | CCDC149 | 91050 | 0 | 0 | 11 | |
| GSE74703 | CCDC149 | 91050 | 0 | 13 | 23 | |
| GSE74704 | CCDC149 | 91050 | 0 | 10 | 10 | |
| TCGA | CCDC149 | 91050 | 11 | 47 | 38 |
Total number of gains: 28; Total number of losses: 185; Total Number of normals: 275.
Somatic mutations of CCDC149:
Generating mutation plots.
Highly correlated genes for CCDC149:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC149 | GABBR1 | 0.730938 | 3 | 0 | 3 |
| CCDC149 | CNTNAP1 | 0.72971 | 3 | 0 | 3 |
| CCDC149 | ID2 | 0.721137 | 4 | 0 | 4 |
| CCDC149 | ZBTB10 | 0.713705 | 3 | 0 | 3 |
| CCDC149 | MED22 | 0.703197 | 3 | 0 | 3 |
| CCDC149 | NR2F2 | 0.699146 | 3 | 0 | 3 |
| CCDC149 | RBM41 | 0.697969 | 3 | 0 | 3 |
| CCDC149 | RGS9 | 0.695551 | 3 | 0 | 3 |
| CCDC149 | F8 | 0.694995 | 3 | 0 | 3 |
| CCDC149 | PRKACA | 0.693985 | 3 | 0 | 3 |
| CCDC149 | KIAA0753 | 0.693045 | 3 | 0 | 3 |
| CCDC149 | YPEL1 | 0.692594 | 3 | 0 | 3 |
| CCDC149 | RGMB | 0.69155 | 3 | 0 | 3 |
| CCDC149 | ANTXR2 | 0.690805 | 3 | 0 | 3 |
| CCDC149 | ITPKB | 0.689637 | 3 | 0 | 3 |
| CCDC149 | CHODL | 0.683831 | 3 | 0 | 3 |
| CCDC149 | RBM26-AS1 | 0.679302 | 3 | 0 | 3 |
| CCDC149 | SDC3 | 0.678408 | 3 | 0 | 3 |
| CCDC149 | KDSR | 0.678001 | 3 | 0 | 3 |
| CCDC149 | LHX3 | 0.675373 | 5 | 0 | 5 |
For details and further investigation, click here
