| Full name: NHL repeat containing 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 283948 | HGNC ID: HGNC:26700 | Ensembl Gene: ENSG00000257108 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NHLRC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NHLRC4 | 283948 | 1558431_at | -0.1167 | 0.6577 | |
| GSE26886 | NHLRC4 | 283948 | 1558431_at | -0.0604 | 0.5204 | |
| GSE45670 | NHLRC4 | 283948 | 1558431_at | 0.0032 | 0.9797 | |
| GSE53622 | NHLRC4 | 283948 | 36045 | -1.1048 | 0.0000 | |
| GSE53624 | NHLRC4 | 283948 | 36045 | -1.6737 | 0.0000 | |
| GSE63941 | NHLRC4 | 283948 | 1558431_at | 0.0746 | 0.6256 | |
| GSE77861 | NHLRC4 | 283948 | 1558431_at | -0.1282 | 0.1987 | |
| GSE97050 | NHLRC4 | 283948 | A_33_P3390187 | -0.0442 | 0.8506 | |
| SRP219564 | NHLRC4 | 283948 | RNAseq | -0.2923 | 0.6417 | |
| TCGA | NHLRC4 | 283948 | RNAseq | -0.4147 | 0.1102 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NHLRC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NHLRC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NHLRC4 | 283948 | 5 | 5 | 20 | |
| GSE20123 | NHLRC4 | 283948 | 5 | 4 | 21 | |
| GSE43470 | NHLRC4 | 283948 | 4 | 7 | 32 | |
| GSE46452 | NHLRC4 | 283948 | 38 | 1 | 20 | |
| GSE47630 | NHLRC4 | 283948 | 13 | 6 | 21 | |
| GSE54993 | NHLRC4 | 283948 | 3 | 5 | 62 | |
| GSE54994 | NHLRC4 | 283948 | 4 | 10 | 39 | |
| GSE60625 | NHLRC4 | 283948 | 4 | 0 | 7 | |
| GSE74703 | NHLRC4 | 283948 | 4 | 5 | 27 | |
| GSE74704 | NHLRC4 | 283948 | 3 | 2 | 15 | |
| TCGA | NHLRC4 | 283948 | 20 | 15 | 61 |
Total number of gains: 103; Total number of losses: 60; Total Number of normals: 325.
Somatic mutations of NHLRC4:
Generating mutation plots.
Highly correlated genes for NHLRC4:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NHLRC4 | RNF222 | 0.86079 | 3 | 0 | 3 |
| NHLRC4 | TIGD5 | 0.811092 | 3 | 0 | 3 |
| NHLRC4 | CLEC18C | 0.80844 | 3 | 0 | 3 |
| NHLRC4 | CLEC12B | 0.805956 | 4 | 0 | 3 |
| NHLRC4 | DNAI2 | 0.79694 | 3 | 0 | 3 |
| NHLRC4 | KRTAP5-5 | 0.792017 | 3 | 0 | 3 |
| NHLRC4 | MAFG | 0.786578 | 3 | 0 | 3 |
| NHLRC4 | BARHL2 | 0.781981 | 3 | 0 | 3 |
| NHLRC4 | TEX13A | 0.781108 | 3 | 0 | 3 |
| NHLRC4 | FAM163B | 0.77717 | 3 | 0 | 3 |
| NHLRC4 | PHLDB3 | 0.777082 | 4 | 0 | 4 |
| NHLRC4 | KRTAP5-4 | 0.76906 | 3 | 0 | 3 |
| NHLRC4 | CDH10 | 0.762908 | 3 | 0 | 3 |
| NHLRC4 | SLC5A11 | 0.761878 | 3 | 0 | 3 |
| NHLRC4 | HPR | 0.751508 | 3 | 0 | 3 |
| NHLRC4 | ADRA1A | 0.741944 | 3 | 0 | 3 |
| NHLRC4 | FFAR2 | 0.738087 | 3 | 0 | 3 |
| NHLRC4 | ZCCHC18 | 0.73694 | 3 | 0 | 3 |
| NHLRC4 | LHX9 | 0.734564 | 3 | 0 | 3 |
| NHLRC4 | FRMPD2 | 0.734365 | 3 | 0 | 3 |
For details and further investigation, click here
