| Full name: dynein axonemal intermediate chain 2 | Alias Symbol: CILD9|DIC2 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 64446 | HGNC ID: HGNC:18744 | Ensembl Gene: ENSG00000171595 | OMIM ID: 605483 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAI2 | 64446 | 221668_s_at | -0.1632 | 0.4013 | |
| GSE20347 | DNAI2 | 64446 | 221668_s_at | -0.0258 | 0.7365 | |
| GSE23400 | DNAI2 | 64446 | 221668_s_at | -0.1261 | 0.0002 | |
| GSE26886 | DNAI2 | 64446 | 221668_s_at | 0.1629 | 0.2153 | |
| GSE29001 | DNAI2 | 64446 | 220636_at | -0.0537 | 0.7620 | |
| GSE38129 | DNAI2 | 64446 | 221668_s_at | -0.0166 | 0.8174 | |
| GSE45670 | DNAI2 | 64446 | 221668_s_at | 0.1122 | 0.1201 | |
| GSE53622 | DNAI2 | 64446 | 34611 | -0.3967 | 0.0050 | |
| GSE53624 | DNAI2 | 64446 | 34611 | -1.1312 | 0.0000 | |
| GSE63941 | DNAI2 | 64446 | 221668_s_at | 0.1765 | 0.3741 | |
| GSE77861 | DNAI2 | 64446 | 221668_s_at | -0.0950 | 0.3145 | |
| TCGA | DNAI2 | 64446 | RNAseq | 0.7399 | 0.4774 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAI2 | 64446 | 3 | 2 | 25 | |
| GSE20123 | DNAI2 | 64446 | 3 | 2 | 25 | |
| GSE43470 | DNAI2 | 64446 | 6 | 3 | 34 | |
| GSE46452 | DNAI2 | 64446 | 33 | 0 | 26 | |
| GSE47630 | DNAI2 | 64446 | 8 | 1 | 31 | |
| GSE54993 | DNAI2 | 64446 | 2 | 5 | 63 | |
| GSE54994 | DNAI2 | 64446 | 10 | 4 | 39 | |
| GSE60625 | DNAI2 | 64446 | 6 | 0 | 5 | |
| GSE74703 | DNAI2 | 64446 | 6 | 1 | 29 | |
| GSE74704 | DNAI2 | 64446 | 3 | 1 | 16 | |
| TCGA | DNAI2 | 64446 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 29; Total Number of normals: 347.
Somatic mutations of DNAI2:
Generating mutation plots.
Highly correlated genes for DNAI2:
Showing top 20/813 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAI2 | NHLRC4 | 0.79694 | 3 | 0 | 3 |
| DNAI2 | NDUFB2-AS1 | 0.733627 | 5 | 0 | 4 |
| DNAI2 | TNFAIP8L2 | 0.725839 | 3 | 0 | 3 |
| DNAI2 | HTR1D | 0.704553 | 3 | 0 | 3 |
| DNAI2 | DCD | 0.703364 | 3 | 0 | 3 |
| DNAI2 | HAMP | 0.701417 | 4 | 0 | 3 |
| DNAI2 | PRL | 0.69698 | 5 | 0 | 5 |
| DNAI2 | NOX3 | 0.694721 | 3 | 0 | 3 |
| DNAI2 | AQP6 | 0.691816 | 5 | 0 | 5 |
| DNAI2 | LCT | 0.685427 | 6 | 0 | 5 |
| DNAI2 | IL22 | 0.681496 | 3 | 0 | 3 |
| DNAI2 | KCNF1 | 0.666232 | 3 | 0 | 3 |
| DNAI2 | MPO | 0.664629 | 5 | 0 | 4 |
| DNAI2 | DIO3 | 0.663872 | 3 | 0 | 3 |
| DNAI2 | IGH | 0.663328 | 3 | 0 | 3 |
| DNAI2 | KCNJ5 | 0.663194 | 3 | 0 | 3 |
| DNAI2 | SPATA25 | 0.662953 | 3 | 0 | 3 |
| DNAI2 | MAG | 0.659086 | 3 | 0 | 3 |
| DNAI2 | GRM6 | 0.657984 | 4 | 0 | 4 |
| DNAI2 | KCNQ3 | 0.65728 | 3 | 0 | 3 |
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