| Full name: FERM and PDZ domain containing 2 | Alias Symbol: MGC35285 | ||
| Type: protein-coding gene | Cytoband: 10q11.22 | ||
| Entrez ID: 143162 | HGNC ID: HGNC:28572 | Ensembl Gene: ENSG00000170324 | OMIM ID: 613323 |
| Drug and gene relationship at DGIdb | |||
Expression of FRMPD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | FRMPD2 | 143162 | 315 | -1.7418 | 0.0000 | |
| GSE53624 | FRMPD2 | 143162 | 315 | -2.4864 | 0.0000 | |
| GSE97050 | FRMPD2 | 143162 | A_23_P86710 | -0.0930 | 0.6484 | |
| SRP133303 | FRMPD2 | 143162 | RNAseq | -0.7106 | 0.0762 | |
| TCGA | FRMPD2 | 143162 | RNAseq | 0.2279 | 0.8768 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FRMPD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRMPD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMPD2 | 143162 | 2 | 6 | 22 | |
| GSE20123 | FRMPD2 | 143162 | 2 | 6 | 22 | |
| GSE43470 | FRMPD2 | 143162 | 1 | 6 | 36 | |
| GSE46452 | FRMPD2 | 143162 | 0 | 13 | 46 | |
| GSE47630 | FRMPD2 | 143162 | 4 | 12 | 24 | |
| GSE54993 | FRMPD2 | 143162 | 9 | 0 | 61 | |
| GSE54994 | FRMPD2 | 143162 | 2 | 10 | 41 | |
| GSE60625 | FRMPD2 | 143162 | 0 | 0 | 11 | |
| GSE74703 | FRMPD2 | 143162 | 1 | 3 | 32 | |
| GSE74704 | FRMPD2 | 143162 | 1 | 5 | 14 | |
| TCGA | FRMPD2 | 143162 | 15 | 20 | 61 |
Total number of gains: 37; Total number of losses: 81; Total Number of normals: 370.
Somatic mutations of FRMPD2:
Generating mutation plots.
Highly correlated genes for FRMPD2:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMPD2 | NHLRC4 | 0.734365 | 3 | 0 | 3 |
| FRMPD2 | KLK2 | 0.733576 | 3 | 0 | 3 |
| FRMPD2 | CLEC12B | 0.713443 | 3 | 0 | 3 |
| FRMPD2 | GPR62 | 0.711912 | 3 | 0 | 3 |
| FRMPD2 | GOLGA2 | 0.702944 | 3 | 0 | 3 |
| FRMPD2 | BTBD9 | 0.696818 | 3 | 0 | 3 |
| FRMPD2 | CARD14 | 0.671436 | 3 | 0 | 3 |
| FRMPD2 | GHRHR | 0.668323 | 3 | 0 | 3 |
| FRMPD2 | KRTAP5-4 | 0.661102 | 3 | 0 | 3 |
| FRMPD2 | PRRG3 | 0.642446 | 3 | 0 | 3 |
| FRMPD2 | MAFG | 0.642124 | 3 | 0 | 3 |
| FRMPD2 | SLC4A3 | 0.625126 | 3 | 0 | 3 |
| FRMPD2 | TTC39A | 0.618726 | 3 | 0 | 3 |
| FRMPD2 | ABLIM3 | 0.612832 | 3 | 0 | 3 |
| FRMPD2 | SLC35C1 | 0.595274 | 3 | 0 | 3 |
| FRMPD2 | TJP2 | 0.582878 | 3 | 0 | 3 |
| FRMPD2 | OR10G3 | 0.581379 | 3 | 0 | 3 |
| FRMPD2 | ESAM | 0.579381 | 3 | 0 | 3 |
| FRMPD2 | ADAMTSL4 | 0.578176 | 3 | 0 | 3 |
| FRMPD2 | PCDH1 | 0.574192 | 3 | 0 | 3 |
For details and further investigation, click here
