| Full name: ligand dependent nuclear receptor corepressor | Alias Symbol: MLR2|FLJ38026|KIAA1795|DKFZP564P1916|FLJ13022 | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 84458 | HGNC ID: HGNC:29503 | Ensembl Gene: ENSG00000196233 | OMIM ID: 607698 |
| Drug and gene relationship at DGIdb | |||
Expression of LCOR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCOR | 84458 | 228454_at | 0.0879 | 0.8991 | |
| GSE26886 | LCOR | 84458 | 228454_at | -0.3434 | 0.2277 | |
| GSE45670 | LCOR | 84458 | 228454_at | 0.2586 | 0.0406 | |
| GSE53622 | LCOR | 84458 | 2615 | -0.4091 | 0.0000 | |
| GSE53624 | LCOR | 84458 | 28362 | -0.3126 | 0.0000 | |
| GSE63941 | LCOR | 84458 | 228454_at | 0.2582 | 0.4466 | |
| GSE77861 | LCOR | 84458 | 228454_at | 0.0139 | 0.9737 | |
| GSE97050 | LCOR | A_21_P0000079 | -0.2556 | 0.2151 | ||
| SRP007169 | LCOR | 84458 | RNAseq | -0.3676 | 0.3371 | |
| SRP008496 | LCOR | 84458 | RNAseq | -0.3333 | 0.0900 | |
| SRP064894 | LCOR | 84458 | RNAseq | -0.6149 | 0.0068 | |
| SRP133303 | LCOR | 84458 | RNAseq | -0.0689 | 0.7192 | |
| SRP159526 | LCOR | 84458 | RNAseq | -0.1656 | 0.6094 | |
| SRP193095 | LCOR | 84458 | RNAseq | -0.5289 | 0.0000 | |
| SRP219564 | LCOR | 84458 | RNAseq | -0.3948 | 0.3746 | |
| TCGA | LCOR | 84458 | RNAseq | -0.1003 | 0.2079 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCOR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCOR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCOR | 84458 | 0 | 8 | 22 | |
| GSE20123 | LCOR | 84458 | 0 | 7 | 23 | |
| GSE43470 | LCOR | 84458 | 0 | 7 | 36 | |
| GSE46452 | LCOR | 84458 | 0 | 11 | 48 | |
| GSE47630 | LCOR | 84458 | 2 | 14 | 24 | |
| GSE54993 | LCOR | 84458 | 7 | 0 | 63 | |
| GSE54994 | LCOR | 84458 | 2 | 10 | 41 | |
| GSE60625 | LCOR | 84458 | 0 | 0 | 11 | |
| GSE74703 | LCOR | 84458 | 0 | 5 | 31 | |
| GSE74704 | LCOR | 84458 | 0 | 4 | 16 | |
| TCGA | LCOR | 84458 | 5 | 28 | 63 |
Total number of gains: 16; Total number of losses: 94; Total Number of normals: 378.
Somatic mutations of LCOR:
Generating mutation plots.
Highly correlated genes for LCOR:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCOR | TMCO4 | 0.833135 | 3 | 0 | 3 |
| LCOR | MCCC1 | 0.806686 | 3 | 0 | 3 |
| LCOR | ZNF564 | 0.800212 | 3 | 0 | 3 |
| LCOR | PAN3 | 0.793005 | 3 | 0 | 3 |
| LCOR | RWDD4 | 0.781536 | 3 | 0 | 3 |
| LCOR | CYTH2 | 0.777623 | 3 | 0 | 3 |
| LCOR | ZNF805 | 0.775584 | 3 | 0 | 3 |
| LCOR | ZSCAN16 | 0.772677 | 3 | 0 | 3 |
| LCOR | AKAP17A | 0.770837 | 3 | 0 | 3 |
| LCOR | NOC3L | 0.770546 | 3 | 0 | 3 |
| LCOR | FAM104B | 0.770055 | 3 | 0 | 3 |
| LCOR | SMARCC2 | 0.767359 | 3 | 0 | 3 |
| LCOR | ZNF317 | 0.766525 | 3 | 0 | 3 |
| LCOR | PIK3CB | 0.763106 | 3 | 0 | 3 |
| LCOR | ZNF394 | 0.754982 | 3 | 0 | 3 |
| LCOR | KDM4B | 0.744931 | 3 | 0 | 3 |
| LCOR | SETD4 | 0.742768 | 3 | 0 | 3 |
| LCOR | SNRNP35 | 0.737931 | 3 | 0 | 3 |
| LCOR | METAP1 | 0.737373 | 3 | 0 | 3 |
| LCOR | EPB41 | 0.737243 | 3 | 0 | 3 |
For details and further investigation, click here
