| Full name: TATA-box binding protein associated factor, RNA polymerase I subunit C | Alias Symbol: TAFI110|TAFI95|SL1|MGC:39976 | ||
| Type: protein-coding gene | Cytoband: 16q24 | ||
| Entrez ID: 9013 | HGNC ID: HGNC:11534 | Ensembl Gene: ENSG00000103168 | OMIM ID: 604905 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TAF1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF1C | 9013 | 203938_s_at | 0.2620 | 0.3839 | |
| GSE20347 | TAF1C | 9013 | 203938_s_at | 0.3102 | 0.0081 | |
| GSE23400 | TAF1C | 9013 | 203938_s_at | 0.1526 | 0.0087 | |
| GSE26886 | TAF1C | 9013 | 203938_s_at | -0.0501 | 0.8473 | |
| GSE29001 | TAF1C | 9013 | 203938_s_at | 0.3711 | 0.1930 | |
| GSE38129 | TAF1C | 9013 | 203938_s_at | 0.3421 | 0.0019 | |
| GSE45670 | TAF1C | 9013 | 203938_s_at | 0.2924 | 0.0182 | |
| GSE53622 | TAF1C | 9013 | 47920 | 0.1727 | 0.0425 | |
| GSE53624 | TAF1C | 9013 | 47920 | 0.2967 | 0.0000 | |
| GSE63941 | TAF1C | 9013 | 203938_s_at | -0.4692 | 0.1406 | |
| GSE77861 | TAF1C | 9013 | 203938_s_at | 0.3953 | 0.0041 | |
| GSE97050 | TAF1C | 9013 | A_23_P163546 | 0.1412 | 0.5463 | |
| SRP007169 | TAF1C | 9013 | RNAseq | 0.2944 | 0.4355 | |
| SRP008496 | TAF1C | 9013 | RNAseq | 0.0413 | 0.8728 | |
| SRP064894 | TAF1C | 9013 | RNAseq | 0.5242 | 0.0070 | |
| SRP133303 | TAF1C | 9013 | RNAseq | 0.1042 | 0.4572 | |
| SRP159526 | TAF1C | 9013 | RNAseq | 0.2445 | 0.2981 | |
| SRP193095 | TAF1C | 9013 | RNAseq | 0.5774 | 0.0000 | |
| SRP219564 | TAF1C | 9013 | RNAseq | 0.1668 | 0.5843 | |
| TCGA | TAF1C | 9013 | RNAseq | 0.0074 | 0.8806 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF1C | 9013 | 4 | 4 | 22 | |
| GSE20123 | TAF1C | 9013 | 4 | 4 | 22 | |
| GSE43470 | TAF1C | 9013 | 2 | 10 | 31 | |
| GSE46452 | TAF1C | 9013 | 37 | 2 | 20 | |
| GSE47630 | TAF1C | 9013 | 11 | 9 | 20 | |
| GSE54993 | TAF1C | 9013 | 3 | 4 | 63 | |
| GSE54994 | TAF1C | 9013 | 8 | 10 | 35 | |
| GSE60625 | TAF1C | 9013 | 4 | 0 | 7 | |
| GSE74703 | TAF1C | 9013 | 2 | 7 | 27 | |
| GSE74704 | TAF1C | 9013 | 3 | 2 | 15 | |
| TCGA | TAF1C | 9013 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 68; Total Number of normals: 316.
Somatic mutations of TAF1C:
Generating mutation plots.
Highly correlated genes for TAF1C:
Showing top 20/557 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF1C | MED22 | 0.816774 | 3 | 0 | 3 |
| TAF1C | DYRK2 | 0.812543 | 3 | 0 | 3 |
| TAF1C | LYRM4 | 0.794031 | 3 | 0 | 3 |
| TAF1C | TADA2A | 0.789312 | 3 | 0 | 3 |
| TAF1C | MMS19 | 0.783902 | 3 | 0 | 3 |
| TAF1C | GPATCH2 | 0.776435 | 3 | 0 | 3 |
| TAF1C | ABCF1 | 0.775075 | 3 | 0 | 3 |
| TAF1C | HNRNPAB | 0.773596 | 3 | 0 | 3 |
| TAF1C | DDB1 | 0.772632 | 3 | 0 | 3 |
| TAF1C | LDLRAP1 | 0.763678 | 3 | 0 | 3 |
| TAF1C | PSMB6 | 0.762371 | 3 | 0 | 3 |
| TAF1C | NAF1 | 0.758676 | 3 | 0 | 3 |
| TAF1C | NOC3L | 0.754791 | 3 | 0 | 3 |
| TAF1C | ELOF1 | 0.754061 | 4 | 0 | 3 |
| TAF1C | TRMT6 | 0.750624 | 3 | 0 | 3 |
| TAF1C | TYW5 | 0.750396 | 3 | 0 | 3 |
| TAF1C | FAM50A | 0.744372 | 3 | 0 | 3 |
| TAF1C | RPL7L1 | 0.743536 | 3 | 0 | 3 |
| TAF1C | EXOC6 | 0.742461 | 3 | 0 | 3 |
| TAF1C | NAB2 | 0.740814 | 4 | 0 | 3 |
For details and further investigation, click here
