| Full name: asteroid homolog 1 | Alias Symbol: HT001 | ||
| Type: protein-coding gene | Cytoband: 3q22.1 | ||
| Entrez ID: 28990 | HGNC ID: HGNC:25021 | Ensembl Gene: ENSG00000034533 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASTE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASTE1 | 28990 | 221135_s_at | 0.4568 | 0.4747 | |
| GSE20347 | ASTE1 | 28990 | 221135_s_at | 0.3441 | 0.0085 | |
| GSE23400 | ASTE1 | 28990 | 221135_s_at | 0.1087 | 0.0312 | |
| GSE26886 | ASTE1 | 28990 | 221135_s_at | -0.0242 | 0.9336 | |
| GSE29001 | ASTE1 | 28990 | 221135_s_at | 0.2553 | 0.4639 | |
| GSE38129 | ASTE1 | 28990 | 221135_s_at | 0.2306 | 0.0348 | |
| GSE45670 | ASTE1 | 28990 | 221135_s_at | 0.2782 | 0.1353 | |
| GSE53622 | ASTE1 | 28990 | 66510 | 0.5849 | 0.0000 | |
| GSE53624 | ASTE1 | 28990 | 94353 | 0.4844 | 0.0000 | |
| GSE63941 | ASTE1 | 28990 | 221135_s_at | 0.4453 | 0.3286 | |
| GSE77861 | ASTE1 | 28990 | 221135_s_at | 0.1629 | 0.5158 | |
| GSE97050 | ASTE1 | 28990 | A_23_P121141 | 0.4117 | 0.2827 | |
| SRP007169 | ASTE1 | 28990 | RNAseq | 0.4614 | 0.3469 | |
| SRP008496 | ASTE1 | 28990 | RNAseq | 0.4882 | 0.1931 | |
| SRP064894 | ASTE1 | 28990 | RNAseq | 0.4768 | 0.0184 | |
| SRP133303 | ASTE1 | 28990 | RNAseq | 0.3877 | 0.0327 | |
| SRP159526 | ASTE1 | 28990 | RNAseq | 0.5435 | 0.0288 | |
| SRP193095 | ASTE1 | 28990 | RNAseq | 0.2458 | 0.0324 | |
| SRP219564 | ASTE1 | 28990 | RNAseq | 0.3799 | 0.1328 | |
| TCGA | ASTE1 | 28990 | RNAseq | 0.0097 | 0.8870 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASTE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASTE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASTE1 | 28990 | 16 | 0 | 14 | |
| GSE20123 | ASTE1 | 28990 | 16 | 0 | 14 | |
| GSE43470 | ASTE1 | 28990 | 20 | 0 | 23 | |
| GSE46452 | ASTE1 | 28990 | 15 | 4 | 40 | |
| GSE47630 | ASTE1 | 28990 | 18 | 3 | 19 | |
| GSE54993 | ASTE1 | 28990 | 2 | 8 | 60 | |
| GSE54994 | ASTE1 | 28990 | 32 | 3 | 18 | |
| GSE60625 | ASTE1 | 28990 | 0 | 6 | 5 | |
| GSE74703 | ASTE1 | 28990 | 18 | 0 | 18 | |
| GSE74704 | ASTE1 | 28990 | 12 | 0 | 8 | |
| TCGA | ASTE1 | 28990 | 58 | 8 | 30 |
Total number of gains: 207; Total number of losses: 32; Total Number of normals: 249.
Somatic mutations of ASTE1:
Generating mutation plots.
Highly correlated genes for ASTE1:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASTE1 | NOC3L | 0.778612 | 3 | 0 | 3 |
| ASTE1 | LRRC34 | 0.763388 | 3 | 0 | 3 |
| ASTE1 | TXLNG | 0.75819 | 3 | 0 | 3 |
| ASTE1 | BUD31 | 0.750078 | 4 | 0 | 4 |
| ASTE1 | EIF3C | 0.725804 | 3 | 0 | 3 |
| ASTE1 | NUB1 | 0.724855 | 3 | 0 | 3 |
| ASTE1 | KLHDC2 | 0.715258 | 3 | 0 | 3 |
| ASTE1 | LRRC58 | 0.710419 | 4 | 0 | 4 |
| ASTE1 | SRSF10 | 0.709682 | 4 | 0 | 3 |
| ASTE1 | NUP54 | 0.707523 | 3 | 0 | 3 |
| ASTE1 | KRR1 | 0.706683 | 3 | 0 | 3 |
| ASTE1 | EP400 | 0.702133 | 4 | 0 | 3 |
| ASTE1 | HNRNPF | 0.69949 | 3 | 0 | 3 |
| ASTE1 | DDX23 | 0.698145 | 4 | 0 | 3 |
| ASTE1 | SPATA2 | 0.695913 | 5 | 0 | 5 |
| ASTE1 | PRDM15 | 0.695882 | 4 | 0 | 3 |
| ASTE1 | NOLC1 | 0.694027 | 3 | 0 | 3 |
| ASTE1 | FAM200A | 0.691547 | 4 | 0 | 3 |
| ASTE1 | MTOR | 0.688391 | 5 | 0 | 4 |
| ASTE1 | RSBN1L | 0.674073 | 4 | 0 | 3 |
For details and further investigation, click here
