| Full name: zinc finger RNA binding protein | Alias Symbol: ZFR1|SPG71 | ||
| Type: protein-coding gene | Cytoband: 5p13.3 | ||
| Entrez ID: 51663 | HGNC ID: HGNC:17277 | Ensembl Gene: ENSG00000056097 | OMIM ID: 615635 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZFR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFR | 51663 | 201857_at | -0.0394 | 0.9065 | |
| GSE20347 | ZFR | 51663 | 201857_at | 0.2568 | 0.0426 | |
| GSE23400 | ZFR | 51663 | 201857_at | 0.3153 | 0.0000 | |
| GSE26886 | ZFR | 51663 | 201857_at | 0.2057 | 0.4255 | |
| GSE29001 | ZFR | 51663 | 201857_at | 0.3591 | 0.0984 | |
| GSE38129 | ZFR | 51663 | 201857_at | 0.1949 | 0.0495 | |
| GSE45670 | ZFR | 51663 | 201857_at | -0.0252 | 0.8521 | |
| GSE53622 | ZFR | 51663 | 158240 | 0.1454 | 0.0134 | |
| GSE53624 | ZFR | 51663 | 29105 | 0.0727 | 0.1751 | |
| GSE63941 | ZFR | 51663 | 201857_at | -0.4396 | 0.1199 | |
| GSE77861 | ZFR | 51663 | 201857_at | 0.4418 | 0.0555 | |
| GSE97050 | ZFR | 51663 | A_24_P311771 | -0.0760 | 0.7070 | |
| SRP007169 | ZFR | 51663 | RNAseq | 0.5372 | 0.0922 | |
| SRP008496 | ZFR | 51663 | RNAseq | 0.6688 | 0.0063 | |
| SRP064894 | ZFR | 51663 | RNAseq | -0.0903 | 0.6075 | |
| SRP133303 | ZFR | 51663 | RNAseq | 0.1818 | 0.1119 | |
| SRP159526 | ZFR | 51663 | RNAseq | 0.2870 | 0.2405 | |
| SRP193095 | ZFR | 51663 | RNAseq | 0.0080 | 0.9193 | |
| SRP219564 | ZFR | 51663 | RNAseq | -0.0945 | 0.6932 | |
| TCGA | ZFR | 51663 | RNAseq | 0.0121 | 0.7730 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZFR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFR | 51663 | 11 | 0 | 19 | |
| GSE20123 | ZFR | 51663 | 11 | 0 | 19 | |
| GSE43470 | ZFR | 51663 | 15 | 3 | 25 | |
| GSE46452 | ZFR | 51663 | 6 | 21 | 32 | |
| GSE47630 | ZFR | 51663 | 6 | 12 | 22 | |
| GSE54993 | ZFR | 51663 | 5 | 4 | 61 | |
| GSE54994 | ZFR | 51663 | 26 | 2 | 25 | |
| GSE60625 | ZFR | 51663 | 0 | 0 | 11 | |
| GSE74703 | ZFR | 51663 | 12 | 2 | 22 | |
| GSE74704 | ZFR | 51663 | 10 | 0 | 10 | |
| TCGA | ZFR | 51663 | 51 | 6 | 39 |
Total number of gains: 153; Total number of losses: 50; Total Number of normals: 285.
Somatic mutations of ZFR:
Generating mutation plots.
Highly correlated genes for ZFR:
Showing top 20/832 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFR | THYN1 | 0.791311 | 3 | 0 | 3 |
| ZFR | SPPL2A | 0.782239 | 3 | 0 | 3 |
| ZFR | FIS1 | 0.744981 | 3 | 0 | 3 |
| ZFR | BEX5 | 0.731173 | 3 | 0 | 3 |
| ZFR | NOC3L | 0.73003 | 4 | 0 | 4 |
| ZFR | ZNF510 | 0.723223 | 3 | 0 | 3 |
| ZFR | SDHAF2 | 0.720921 | 3 | 0 | 3 |
| ZFR | AGTPBP1 | 0.719893 | 3 | 0 | 3 |
| ZFR | KRR1 | 0.718483 | 5 | 0 | 4 |
| ZFR | NPAT | 0.718343 | 3 | 0 | 3 |
| ZFR | MLLT3 | 0.713194 | 4 | 0 | 3 |
| ZFR | TXNDC16 | 0.708208 | 3 | 0 | 3 |
| ZFR | MTFMT | 0.704632 | 4 | 0 | 4 |
| ZFR | PAIP1 | 0.70301 | 9 | 0 | 9 |
| ZFR | NR3C2 | 0.702366 | 3 | 0 | 3 |
| ZFR | ERI2 | 0.702152 | 3 | 0 | 3 |
| ZFR | UTP14C | 0.701947 | 3 | 0 | 3 |
| ZFR | TMEM150C | 0.699612 | 3 | 0 | 3 |
| ZFR | FILIP1 | 0.696726 | 3 | 0 | 3 |
| ZFR | RPP38 | 0.69435 | 3 | 0 | 3 |
For details and further investigation, click here
