| Full name: NOP16 nucleolar protein | Alias Symbol: HSPC111|HSPC185|LOC51491 | ||
| Type: protein-coding gene | Cytoband: 5q35.2 | ||
| Entrez ID: 51491 | HGNC ID: HGNC:26934 | Ensembl Gene: ENSG00000048162 | OMIM ID: 612861 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOP16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOP16 | 51491 | 214011_s_at | 0.6454 | 0.1306 | |
| GSE20347 | NOP16 | 51491 | 214011_s_at | -0.0297 | 0.8909 | |
| GSE23400 | NOP16 | 51491 | 214011_s_at | 0.1899 | 0.0397 | |
| GSE26886 | NOP16 | 51491 | 214011_s_at | -0.0114 | 0.9736 | |
| GSE29001 | NOP16 | 51491 | 214011_s_at | 0.0937 | 0.7613 | |
| GSE38129 | NOP16 | 51491 | 214011_s_at | 0.3350 | 0.0598 | |
| GSE45670 | NOP16 | 51491 | 214011_s_at | 0.2654 | 0.1890 | |
| GSE53622 | NOP16 | 51491 | 34763 | 0.0505 | 0.7072 | |
| GSE53624 | NOP16 | 51491 | 34763 | 0.0692 | 0.3506 | |
| GSE63941 | NOP16 | 51491 | 214011_s_at | 1.0377 | 0.0380 | |
| GSE77861 | NOP16 | 51491 | 214011_s_at | -0.0744 | 0.7641 | |
| GSE97050 | NOP16 | 51491 | A_33_P3361257 | 0.4322 | 0.2151 | |
| SRP007169 | NOP16 | 51491 | RNAseq | -0.2769 | 0.4093 | |
| SRP008496 | NOP16 | 51491 | RNAseq | -0.3761 | 0.0764 | |
| SRP064894 | NOP16 | 51491 | RNAseq | -0.0016 | 0.9951 | |
| SRP133303 | NOP16 | 51491 | RNAseq | 0.2346 | 0.2916 | |
| SRP159526 | NOP16 | 51491 | RNAseq | -0.3313 | 0.3134 | |
| SRP193095 | NOP16 | 51491 | RNAseq | -0.2204 | 0.2058 | |
| SRP219564 | NOP16 | 51491 | RNAseq | 0.1087 | 0.8435 | |
| TCGA | NOP16 | 51491 | RNAseq | 0.1864 | 0.0155 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOP16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOP16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP16 | 51491 | 2 | 13 | 15 | |
| GSE20123 | NOP16 | 51491 | 2 | 13 | 15 | |
| GSE43470 | NOP16 | 51491 | 1 | 11 | 31 | |
| GSE46452 | NOP16 | 51491 | 0 | 27 | 32 | |
| GSE47630 | NOP16 | 51491 | 0 | 20 | 20 | |
| GSE54993 | NOP16 | 51491 | 10 | 2 | 58 | |
| GSE54994 | NOP16 | 51491 | 2 | 17 | 34 | |
| GSE60625 | NOP16 | 51491 | 1 | 0 | 10 | |
| GSE74703 | NOP16 | 51491 | 1 | 7 | 28 | |
| GSE74704 | NOP16 | 51491 | 1 | 6 | 13 | |
| TCGA | NOP16 | 51491 | 7 | 35 | 54 |
Total number of gains: 27; Total number of losses: 151; Total Number of normals: 310.
Somatic mutations of NOP16:
Generating mutation plots.
Highly correlated genes for NOP16:
Showing top 20/553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP16 | CKAP2 | 0.718972 | 3 | 0 | 3 |
| NOP16 | RNF149 | 0.710433 | 3 | 0 | 3 |
| NOP16 | WDR5 | 0.689947 | 3 | 0 | 3 |
| NOP16 | NOP14 | 0.6873 | 6 | 0 | 5 |
| NOP16 | TMEM86B | 0.67697 | 3 | 0 | 3 |
| NOP16 | RPL26L1 | 0.675303 | 9 | 0 | 9 |
| NOP16 | ENTPD7 | 0.670955 | 3 | 0 | 3 |
| NOP16 | C6orf62 | 0.669274 | 3 | 0 | 3 |
| NOP16 | MRTO4 | 0.663199 | 11 | 0 | 10 |
| NOP16 | BNIP1 | 0.661531 | 7 | 0 | 7 |
| NOP16 | STK35 | 0.660128 | 3 | 0 | 3 |
| NOP16 | SLC35C2 | 0.658466 | 4 | 0 | 3 |
| NOP16 | ZBTB9 | 0.65791 | 4 | 0 | 3 |
| NOP16 | HNRNPAB | 0.64936 | 13 | 0 | 9 |
| NOP16 | RRP36 | 0.6484 | 5 | 0 | 4 |
| NOP16 | BUB3 | 0.648359 | 4 | 0 | 3 |
| NOP16 | NAA25 | 0.648064 | 5 | 0 | 4 |
| NOP16 | SLC25A19 | 0.647388 | 4 | 0 | 3 |
| NOP16 | C20orf27 | 0.642865 | 4 | 0 | 3 |
| NOP16 | SRSF1 | 0.642682 | 4 | 0 | 3 |
For details and further investigation, click here
