| Full name: transmembrane protein 86B | Alias Symbol: MGC30208 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 255043 | HGNC ID: HGNC:28448 | Ensembl Gene: ENSG00000180089 | OMIM ID: 617806 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM86B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM86B | 255043 | 229736_at | 0.2788 | 0.2988 | |
| GSE26886 | TMEM86B | 255043 | 229736_at | 0.0098 | 0.9466 | |
| GSE45670 | TMEM86B | 255043 | 229736_at | 0.2275 | 0.0195 | |
| GSE53622 | TMEM86B | 255043 | 126876 | 0.1595 | 0.1397 | |
| GSE53624 | TMEM86B | 255043 | 126876 | 0.2615 | 0.0008 | |
| GSE63941 | TMEM86B | 255043 | 229736_at | 0.2067 | 0.3385 | |
| GSE77861 | TMEM86B | 255043 | 229736_at | -0.1059 | 0.2925 | |
| GSE97050 | TMEM86B | 255043 | A_24_P121956 | 0.4048 | 0.1657 | |
| SRP064894 | TMEM86B | 255043 | RNAseq | 0.7347 | 0.0149 | |
| SRP133303 | TMEM86B | 255043 | RNAseq | -0.1111 | 0.6230 | |
| SRP159526 | TMEM86B | 255043 | RNAseq | 0.0574 | 0.9226 | |
| SRP219564 | TMEM86B | 255043 | RNAseq | 0.3428 | 0.2838 | |
| TCGA | TMEM86B | 255043 | RNAseq | -0.5693 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM86B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM86B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM86B | 255043 | 3 | 4 | 23 | |
| GSE20123 | TMEM86B | 255043 | 3 | 3 | 24 | |
| GSE43470 | TMEM86B | 255043 | 3 | 11 | 29 | |
| GSE46452 | TMEM86B | 255043 | 45 | 1 | 13 | |
| GSE47630 | TMEM86B | 255043 | 8 | 6 | 26 | |
| GSE54993 | TMEM86B | 255043 | 17 | 4 | 49 | |
| GSE54994 | TMEM86B | 255043 | 4 | 13 | 36 | |
| GSE60625 | TMEM86B | 255043 | 9 | 0 | 2 | |
| GSE74703 | TMEM86B | 255043 | 3 | 7 | 26 | |
| GSE74704 | TMEM86B | 255043 | 3 | 1 | 16 | |
| TCGA | TMEM86B | 255043 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 64; Total Number of normals: 307.
Somatic mutations of TMEM86B:
Generating mutation plots.
Highly correlated genes for TMEM86B:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM86B | BCL2L1 | 0.781516 | 3 | 0 | 3 |
| TMEM86B | RFX1 | 0.77993 | 3 | 0 | 3 |
| TMEM86B | IFNGR2 | 0.756765 | 3 | 0 | 3 |
| TMEM86B | TBC1D22B | 0.740394 | 3 | 0 | 3 |
| TMEM86B | NCOA6 | 0.736633 | 3 | 0 | 3 |
| TMEM86B | ZNF419 | 0.716829 | 3 | 0 | 3 |
| TMEM86B | HNRNPAB | 0.715492 | 3 | 0 | 3 |
| TMEM86B | STRN4 | 0.708115 | 3 | 0 | 3 |
| TMEM86B | CCDC15 | 0.706913 | 3 | 0 | 3 |
| TMEM86B | PIF1 | 0.69688 | 3 | 0 | 3 |
| TMEM86B | CEP41 | 0.693288 | 3 | 0 | 3 |
| TMEM86B | KHSRP | 0.686048 | 4 | 0 | 3 |
| TMEM86B | TRIT1 | 0.685719 | 3 | 0 | 3 |
| TMEM86B | ROMO1 | 0.683653 | 3 | 0 | 3 |
| TMEM86B | XYLB | 0.679104 | 3 | 0 | 3 |
| TMEM86B | NOP16 | 0.67697 | 3 | 0 | 3 |
| TMEM86B | KCND1 | 0.674904 | 3 | 0 | 3 |
| TMEM86B | CPNE1 | 0.674188 | 3 | 0 | 3 |
| TMEM86B | NAA10 | 0.67353 | 3 | 0 | 3 |
| TMEM86B | RAD18 | 0.66936 | 3 | 0 | 3 |
For details and further investigation, click here
