| Full name: MRT4 homolog, ribosome maturation factor | Alias Symbol: dJ657E11.4|MRT4 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 51154 | HGNC ID: HGNC:18477 | Ensembl Gene: ENSG00000053372 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRTO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRTO4 | 51154 | 220688_s_at | 0.7815 | 0.1636 | |
| GSE20347 | MRTO4 | 51154 | 220688_s_at | 0.4206 | 0.0247 | |
| GSE23400 | MRTO4 | 51154 | 220688_s_at | 0.4837 | 0.0000 | |
| GSE26886 | MRTO4 | 51154 | 220688_s_at | 0.1908 | 0.4702 | |
| GSE29001 | MRTO4 | 51154 | 220688_s_at | 0.4815 | 0.1415 | |
| GSE38129 | MRTO4 | 51154 | 220688_s_at | 0.6673 | 0.0000 | |
| GSE45670 | MRTO4 | 51154 | 220688_s_at | 0.3875 | 0.0400 | |
| GSE53622 | MRTO4 | 51154 | 22987 | 0.3115 | 0.0057 | |
| GSE53624 | MRTO4 | 51154 | 22987 | 0.6217 | 0.0000 | |
| GSE63941 | MRTO4 | 51154 | 220688_s_at | 1.0225 | 0.0028 | |
| GSE77861 | MRTO4 | 51154 | 220688_s_at | 0.1574 | 0.5190 | |
| GSE97050 | MRTO4 | 51154 | A_33_P3357580 | 0.4548 | 0.1307 | |
| SRP007169 | MRTO4 | 51154 | RNAseq | 0.3235 | 0.4313 | |
| SRP008496 | MRTO4 | 51154 | RNAseq | 0.3099 | 0.2278 | |
| SRP064894 | MRTO4 | 51154 | RNAseq | 0.6269 | 0.0060 | |
| SRP133303 | MRTO4 | 51154 | RNAseq | 0.6049 | 0.0002 | |
| SRP159526 | MRTO4 | 51154 | RNAseq | 0.3552 | 0.3107 | |
| SRP193095 | MRTO4 | 51154 | RNAseq | 0.2918 | 0.0052 | |
| SRP219564 | MRTO4 | 51154 | RNAseq | 0.4120 | 0.2720 | |
| TCGA | MRTO4 | 51154 | RNAseq | 0.2816 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRTO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRTO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRTO4 | 51154 | 0 | 5 | 25 | |
| GSE20123 | MRTO4 | 51154 | 0 | 4 | 26 | |
| GSE43470 | MRTO4 | 51154 | 0 | 8 | 35 | |
| GSE46452 | MRTO4 | 51154 | 5 | 1 | 53 | |
| GSE47630 | MRTO4 | 51154 | 8 | 3 | 29 | |
| GSE54993 | MRTO4 | 51154 | 3 | 1 | 66 | |
| GSE54994 | MRTO4 | 51154 | 11 | 4 | 38 | |
| GSE60625 | MRTO4 | 51154 | 0 | 0 | 11 | |
| GSE74703 | MRTO4 | 51154 | 0 | 5 | 31 | |
| GSE74704 | MRTO4 | 51154 | 0 | 0 | 20 | |
| TCGA | MRTO4 | 51154 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of MRTO4:
Generating mutation plots.
Highly correlated genes for MRTO4:
Showing top 20/1339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRTO4 | TARDBP | 0.775532 | 6 | 0 | 6 |
| MRTO4 | ARFGEF2 | 0.773338 | 3 | 0 | 3 |
| MRTO4 | TRUB1 | 0.76963 | 3 | 0 | 3 |
| MRTO4 | AP3D1 | 0.760586 | 3 | 0 | 3 |
| MRTO4 | SPNS1 | 0.759997 | 3 | 0 | 3 |
| MRTO4 | AMD1 | 0.736521 | 3 | 0 | 3 |
| MRTO4 | YWHAG | 0.730254 | 4 | 0 | 4 |
| MRTO4 | ALMS1 | 0.718973 | 3 | 0 | 3 |
| MRTO4 | NEMF | 0.717721 | 3 | 0 | 3 |
| MRTO4 | ZSCAN29 | 0.715668 | 3 | 0 | 3 |
| MRTO4 | MICALCL | 0.714532 | 3 | 0 | 3 |
| MRTO4 | C8orf76 | 0.713803 | 5 | 0 | 5 |
| MRTO4 | PSMG3 | 0.713324 | 5 | 0 | 5 |
| MRTO4 | TRMT6 | 0.71225 | 4 | 0 | 4 |
| MRTO4 | DHX37 | 0.707183 | 5 | 0 | 4 |
| MRTO4 | MED26 | 0.706067 | 3 | 0 | 3 |
| MRTO4 | TMEM44 | 0.703355 | 4 | 0 | 4 |
| MRTO4 | SS18 | 0.702449 | 3 | 0 | 3 |
| MRTO4 | TUBGCP4 | 0.701569 | 7 | 0 | 7 |
| MRTO4 | PPP2R3C | 0.701128 | 3 | 0 | 3 |
For details and further investigation, click here
