C20orf27

 

Full name: chromosome 20 open reading frame 27 Alias Symbol: FLJ20550
Type: protein-coding gene Cytoband: 20p13
Entrez ID: 54976 HGNC ID: HGNC:15873 Ensembl Gene: ENSG00000101220 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C20orf27:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C20orf27 54976 218081_at 0.9004 0.0123
GSE20347 C20orf27 54976 218081_at 0.8146 0.0000
GSE23400 C20orf27 54976 218081_at 0.2686 0.0000
GSE26886 C20orf27 54976 218081_at 0.6666 0.0016
GSE29001 C20orf27 54976 218081_at 0.4281 0.1859
GSE38129 C20orf27 54976 218081_at 0.7125 0.0000
GSE45670 C20orf27 54976 218081_at 0.3988 0.0113
GSE53622 C20orf27 54976 59126 0.4849 0.0000
GSE53624 C20orf27 54976 59126 1.1453 0.0000
GSE63941 C20orf27 54976 50314_i_at 1.4878 0.0001
GSE77861 C20orf27 54976 218081_at 0.4162 0.0242
GSE97050 C20orf27 54976 A_33_P3399433 0.2892 0.5533
SRP007169 C20orf27 54976 RNAseq 0.2860 0.5000
SRP008496 C20orf27 54976 RNAseq 0.6877 0.0221
SRP064894 C20orf27 54976 RNAseq 1.4233 0.0001
SRP133303 C20orf27 54976 RNAseq 0.5106 0.0037
SRP159526 C20orf27 54976 RNAseq 0.9938 0.0032
SRP193095 C20orf27 54976 RNAseq 0.8567 0.0000
SRP219564 C20orf27 54976 RNAseq -0.0411 0.9511
TCGA C20orf27 54976 RNAseq 0.3378 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by C20orf27 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C20orf27:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C20orf27 54976 12 3 15
GSE20123 C20orf27 54976 13 3 14
GSE43470 C20orf27 54976 10 1 32
GSE46452 C20orf27 54976 26 1 32
GSE47630 C20orf27 54976 18 4 18
GSE54993 C20orf27 54976 2 14 54
GSE54994 C20orf27 54976 24 2 27
GSE60625 C20orf27 54976 0 0 11
GSE74703 C20orf27 54976 9 1 26
GSE74704 C20orf27 54976 8 1 11
TCGA C20orf27 54976 39 11 46

Total number of gains: 161; Total number of losses: 41; Total Number of normals: 286.  

 

Somatic mutations of C20orf27:

 

Generating mutation plots.

 

Highly correlated genes for C20orf27:

 

Showing top 20/1901 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C20orf27HMBOX10.807526303
C20orf27SLC7A6OS0.776512404
C20orf27EXOSC100.76571303
C20orf27CDCA20.754865505
C20orf27TRMT2B0.754317303
C20orf27POLR2A0.741818303
C20orf27RAVER10.738841505
C20orf27MAP2K50.735842303
C20orf27PSMA70.730905808
C20orf27SMAD10.729791303
C20orf27TET10.723885303
C20orf27MMS190.721593303
C20orf27FADS10.720503303
C20orf27POLDIP20.719249303
C20orf27MRPL380.717698403
C20orf27ARHGEF110.717393303
C20orf27TRAPPC10.716194303
C20orf27NDUFB90.713699707
C20orf27CD2BP20.712574404
C20orf27SNRPB20.71239810010

For details and further investigation, click here