| Full name: ring finger protein 149 | Alias Symbol: FLJ90504 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 284996 | HGNC ID: HGNC:23137 | Ensembl Gene: ENSG00000163162 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF149:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF149 | 284996 | 225414_at | 0.5174 | 0.3093 | |
| GSE26886 | RNF149 | 284996 | 225414_at | -1.6573 | 0.0000 | |
| GSE45670 | RNF149 | 284996 | 225414_at | 0.5001 | 0.0000 | |
| GSE53622 | RNF149 | 284996 | 15495 | -0.1531 | 0.0976 | |
| GSE53624 | RNF149 | 284996 | 15495 | 0.0259 | 0.6721 | |
| GSE63941 | RNF149 | 284996 | 225414_at | -0.3296 | 0.4102 | |
| GSE77861 | RNF149 | 284996 | 225414_at | 0.1564 | 0.5730 | |
| GSE97050 | RNF149 | 284996 | A_23_P120153 | 0.3948 | 0.3394 | |
| SRP007169 | RNF149 | 284996 | RNAseq | -0.7287 | 0.0108 | |
| SRP008496 | RNF149 | 284996 | RNAseq | -0.7233 | 0.0001 | |
| SRP064894 | RNF149 | 284996 | RNAseq | 0.1243 | 0.4043 | |
| SRP133303 | RNF149 | 284996 | RNAseq | 0.4048 | 0.0148 | |
| SRP159526 | RNF149 | 284996 | RNAseq | -0.2394 | 0.4316 | |
| SRP193095 | RNF149 | 284996 | RNAseq | -0.1850 | 0.1322 | |
| SRP219564 | RNF149 | 284996 | RNAseq | -0.2852 | 0.5704 | |
| TCGA | RNF149 | 284996 | RNAseq | 0.1998 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RNF149 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF149:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF149 | 284996 | 5 | 2 | 23 | |
| GSE20123 | RNF149 | 284996 | 5 | 2 | 23 | |
| GSE43470 | RNF149 | 284996 | 5 | 1 | 37 | |
| GSE46452 | RNF149 | 284996 | 1 | 4 | 54 | |
| GSE47630 | RNF149 | 284996 | 7 | 0 | 33 | |
| GSE54993 | RNF149 | 284996 | 0 | 6 | 64 | |
| GSE54994 | RNF149 | 284996 | 11 | 0 | 42 | |
| GSE60625 | RNF149 | 284996 | 0 | 3 | 8 | |
| GSE74703 | RNF149 | 284996 | 5 | 1 | 30 | |
| GSE74704 | RNF149 | 284996 | 3 | 1 | 16 | |
| TCGA | RNF149 | 284996 | 35 | 5 | 56 |
Total number of gains: 77; Total number of losses: 25; Total Number of normals: 386.
Somatic mutations of RNF149:
Generating mutation plots.
Highly correlated genes for RNF149:
Showing top 20/588 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF149 | LACTB | 0.796738 | 3 | 0 | 3 |
| RNF149 | NCBP1 | 0.794464 | 4 | 0 | 4 |
| RNF149 | PPP4R2 | 0.792938 | 3 | 0 | 3 |
| RNF149 | NAA40 | 0.785535 | 3 | 0 | 3 |
| RNF149 | IL1RL2 | 0.776268 | 3 | 0 | 3 |
| RNF149 | PTBP3 | 0.775792 | 3 | 0 | 3 |
| RNF149 | RFWD3 | 0.770676 | 3 | 0 | 3 |
| RNF149 | CKAP2 | 0.770225 | 3 | 0 | 3 |
| RNF149 | TOP2A | 0.764477 | 3 | 0 | 3 |
| RNF149 | LRP8 | 0.76445 | 3 | 0 | 3 |
| RNF149 | UNC5B | 0.76399 | 4 | 0 | 4 |
| RNF149 | FRMD4B | 0.763731 | 3 | 0 | 3 |
| RNF149 | PUS7L | 0.761025 | 3 | 0 | 3 |
| RNF149 | SERBP1 | 0.75881 | 3 | 0 | 3 |
| RNF149 | SRRD | 0.758145 | 3 | 0 | 3 |
| RNF149 | RBL1 | 0.754676 | 3 | 0 | 3 |
| RNF149 | VPS16 | 0.75447 | 3 | 0 | 3 |
| RNF149 | LARP1 | 0.75327 | 3 | 0 | 3 |
| RNF149 | EXOC6B | 0.753072 | 3 | 0 | 3 |
| RNF149 | SRPRB | 0.752584 | 3 | 0 | 3 |
For details and further investigation, click here
