| Full name: NOP14 nucleolar protein | Alias Symbol: RES4-25|UTP2 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 8602 | HGNC ID: HGNC:16821 | Ensembl Gene: ENSG00000087269 | OMIM ID: 611526 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOP14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOP14 | 8602 | 214661_s_at | 0.7574 | 0.1557 | |
| GSE20347 | NOP14 | 8602 | 214661_s_at | 0.1034 | 0.5386 | |
| GSE23400 | NOP14 | 8602 | 214661_s_at | 0.2610 | 0.0000 | |
| GSE26886 | NOP14 | 8602 | 214661_s_at | 0.7337 | 0.0000 | |
| GSE29001 | NOP14 | 8602 | 214661_s_at | 0.2244 | 0.5173 | |
| GSE38129 | NOP14 | 8602 | 214661_s_at | 0.2677 | 0.0218 | |
| GSE45670 | NOP14 | 8602 | 214661_s_at | 0.2830 | 0.0069 | |
| GSE63941 | NOP14 | 8602 | 214661_s_at | -0.3145 | 0.3919 | |
| GSE77861 | NOP14 | 8602 | 214661_s_at | 0.3170 | 0.3822 | |
| GSE97050 | NOP14 | 8602 | A_32_P22622 | 0.3923 | 0.2155 | |
| SRP007169 | NOP14 | 8602 | RNAseq | 0.9096 | 0.0670 | |
| SRP008496 | NOP14 | 8602 | RNAseq | 0.9167 | 0.0047 | |
| SRP064894 | NOP14 | 8602 | RNAseq | 0.0207 | 0.9064 | |
| SRP133303 | NOP14 | 8602 | RNAseq | 0.0671 | 0.5303 | |
| SRP159526 | NOP14 | 8602 | RNAseq | -0.0334 | 0.8854 | |
| SRP193095 | NOP14 | 8602 | RNAseq | 0.0551 | 0.6111 | |
| SRP219564 | NOP14 | 8602 | RNAseq | 0.2818 | 0.4725 | |
| TCGA | NOP14 | 8602 | RNAseq | 0.0272 | 0.6044 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOP14 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NOP14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP14 | 8602 | 0 | 16 | 14 | |
| GSE20123 | NOP14 | 8602 | 0 | 16 | 14 | |
| GSE43470 | NOP14 | 8602 | 0 | 17 | 26 | |
| GSE46452 | NOP14 | 8602 | 1 | 36 | 22 | |
| GSE47630 | NOP14 | 8602 | 1 | 19 | 20 | |
| GSE54993 | NOP14 | 8602 | 10 | 0 | 60 | |
| GSE54994 | NOP14 | 8602 | 3 | 12 | 38 | |
| GSE60625 | NOP14 | 8602 | 0 | 0 | 11 | |
| GSE74703 | NOP14 | 8602 | 0 | 13 | 23 | |
| GSE74704 | NOP14 | 8602 | 0 | 8 | 12 | |
| TCGA | NOP14 | 8602 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 185; Total Number of normals: 281.
Somatic mutations of NOP14:
Generating mutation plots.
Highly correlated genes for NOP14:
Showing top 20/878 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP14 | LY6K | 0.772669 | 3 | 0 | 3 |
| NOP14 | DNAJB11 | 0.759749 | 3 | 0 | 3 |
| NOP14 | TOP1MT | 0.753657 | 5 | 0 | 5 |
| NOP14 | CNTROB | 0.730272 | 4 | 0 | 4 |
| NOP14 | HOXD13 | 0.728687 | 4 | 0 | 3 |
| NOP14 | CMSS1 | 0.726465 | 3 | 0 | 3 |
| NOP14 | RIOK1 | 0.7237 | 4 | 0 | 4 |
| NOP14 | AGO2 | 0.720624 | 3 | 0 | 3 |
| NOP14 | XPO5 | 0.717657 | 4 | 0 | 3 |
| NOP14 | PKN3 | 0.71617 | 3 | 0 | 3 |
| NOP14 | GEN1 | 0.713283 | 3 | 0 | 3 |
| NOP14 | UHMK1 | 0.709693 | 3 | 0 | 3 |
| NOP14 | ARHGAP39 | 0.709217 | 3 | 0 | 3 |
| NOP14 | C12orf45 | 0.703594 | 5 | 0 | 5 |
| NOP14 | TFR2 | 0.703421 | 3 | 0 | 3 |
| NOP14 | MDK | 0.701923 | 3 | 0 | 3 |
| NOP14 | B3GALT6 | 0.700854 | 4 | 0 | 4 |
| NOP14 | HDGF | 0.700763 | 7 | 0 | 7 |
| NOP14 | ROMO1 | 0.700165 | 3 | 0 | 3 |
| NOP14 | ZNF680 | 0.699835 | 3 | 0 | 3 |
For details and further investigation, click here
