| Full name: nudix hydrolase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 318 | HGNC ID: HGNC:8049 | Ensembl Gene: ENSG00000164978 | OMIM ID: 602852 |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT2 | 318 | 218609_s_at | -0.6247 | 0.4399 | |
| GSE20347 | NUDT2 | 318 | 218609_s_at | -0.3384 | 0.0231 | |
| GSE23400 | NUDT2 | 318 | 218609_s_at | -0.1226 | 0.0389 | |
| GSE26886 | NUDT2 | 318 | 218609_s_at | 0.5977 | 0.0088 | |
| GSE29001 | NUDT2 | 318 | 218609_s_at | -0.1197 | 0.7477 | |
| GSE38129 | NUDT2 | 318 | 218609_s_at | -0.3799 | 0.0055 | |
| GSE45670 | NUDT2 | 318 | 218609_s_at | -0.3876 | 0.0527 | |
| GSE53622 | NUDT2 | 318 | 32736 | -0.3977 | 0.0001 | |
| GSE53624 | NUDT2 | 318 | 32736 | -0.3414 | 0.0008 | |
| GSE63941 | NUDT2 | 318 | 218609_s_at | -0.8495 | 0.0646 | |
| GSE77861 | NUDT2 | 318 | 218609_s_at | -0.3064 | 0.1266 | |
| GSE97050 | NUDT2 | 318 | A_23_P112478 | -0.1973 | 0.3263 | |
| SRP007169 | NUDT2 | 318 | RNAseq | -0.7974 | 0.1940 | |
| SRP008496 | NUDT2 | 318 | RNAseq | -0.4626 | 0.2090 | |
| SRP064894 | NUDT2 | 318 | RNAseq | 0.0512 | 0.8409 | |
| SRP133303 | NUDT2 | 318 | RNAseq | -0.5263 | 0.0097 | |
| SRP159526 | NUDT2 | 318 | RNAseq | -0.4224 | 0.1850 | |
| SRP193095 | NUDT2 | 318 | RNAseq | -0.8426 | 0.0000 | |
| SRP219564 | NUDT2 | 318 | RNAseq | -0.2807 | 0.4277 | |
| TCGA | NUDT2 | 318 | RNAseq | -0.0574 | 0.4929 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT2 | 318 | 4 | 13 | 13 | |
| GSE20123 | NUDT2 | 318 | 4 | 13 | 13 | |
| GSE43470 | NUDT2 | 318 | 3 | 10 | 30 | |
| GSE46452 | NUDT2 | 318 | 6 | 15 | 38 | |
| GSE47630 | NUDT2 | 318 | 1 | 20 | 19 | |
| GSE54993 | NUDT2 | 318 | 6 | 0 | 64 | |
| GSE54994 | NUDT2 | 318 | 6 | 12 | 35 | |
| GSE60625 | NUDT2 | 318 | 0 | 0 | 11 | |
| GSE74703 | NUDT2 | 318 | 2 | 7 | 27 | |
| GSE74704 | NUDT2 | 318 | 0 | 11 | 9 | |
| TCGA | NUDT2 | 318 | 16 | 44 | 36 |
Total number of gains: 48; Total number of losses: 145; Total Number of normals: 295.
Somatic mutations of NUDT2:
Generating mutation plots.
Highly correlated genes for NUDT2:
Showing top 20/259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT2 | ORAI3 | 0.810746 | 3 | 0 | 3 |
| NUDT2 | CUEDC1 | 0.735643 | 3 | 0 | 3 |
| NUDT2 | ZMAT1 | 0.719408 | 3 | 0 | 3 |
| NUDT2 | PCDH18 | 0.716939 | 3 | 0 | 3 |
| NUDT2 | ABCB4 | 0.70581 | 3 | 0 | 3 |
| NUDT2 | SLU7 | 0.704601 | 3 | 0 | 3 |
| NUDT2 | ZBTB10 | 0.701179 | 3 | 0 | 3 |
| NUDT2 | PODN | 0.694918 | 3 | 0 | 3 |
| NUDT2 | LRRC47 | 0.691594 | 3 | 0 | 3 |
| NUDT2 | CSNK1G3 | 0.685516 | 3 | 0 | 3 |
| NUDT2 | RPUSD4 | 0.67441 | 3 | 0 | 3 |
| NUDT2 | TMEM129 | 0.671619 | 3 | 0 | 3 |
| NUDT2 | ATP8B2 | 0.668501 | 3 | 0 | 3 |
| NUDT2 | ARHGAP31 | 0.660826 | 4 | 0 | 3 |
| NUDT2 | AFF3 | 0.65623 | 4 | 0 | 3 |
| NUDT2 | OLFM1 | 0.653966 | 4 | 0 | 3 |
| NUDT2 | ZFYVE26 | 0.653314 | 3 | 0 | 3 |
| NUDT2 | JAG1 | 0.652987 | 3 | 0 | 3 |
| NUDT2 | ATP6AP1 | 0.652002 | 4 | 0 | 3 |
| NUDT2 | FUNDC2 | 0.646148 | 4 | 0 | 4 |
For details and further investigation, click here
