| Full name: podocan | Alias Symbol: PCAN|PODOCAN|MGC24995|SLRR5A | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 127435 | HGNC ID: HGNC:23174 | Ensembl Gene: ENSG00000174348 | OMIM ID: 608661 |
| Drug and gene relationship at DGIdb | |||
Expression of PODN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PODN | 127435 | 226522_at | -0.8861 | 0.2297 | |
| GSE26886 | PODN | 127435 | 233148_at | -0.0757 | 0.5213 | |
| GSE45670 | PODN | 127435 | 233148_at | -0.1446 | 0.0262 | |
| GSE53622 | PODN | 127435 | 116912 | -1.1249 | 0.0000 | |
| GSE53624 | PODN | 127435 | 116912 | -1.0539 | 0.0000 | |
| GSE63941 | PODN | 127435 | 233148_at | -0.4495 | 0.0173 | |
| GSE77861 | PODN | 127435 | 226522_at | -0.1301 | 0.2127 | |
| GSE97050 | PODN | 127435 | A_23_P368154 | -0.5137 | 0.1785 | |
| SRP007169 | PODN | 127435 | RNAseq | 2.3073 | 0.0004 | |
| SRP008496 | PODN | 127435 | RNAseq | 2.0523 | 0.0000 | |
| SRP064894 | PODN | 127435 | RNAseq | 0.0676 | 0.8964 | |
| SRP133303 | PODN | 127435 | RNAseq | -1.0141 | 0.0003 | |
| SRP159526 | PODN | 127435 | RNAseq | -0.8028 | 0.0838 | |
| SRP219564 | PODN | 127435 | RNAseq | -0.1150 | 0.8972 | |
| TCGA | PODN | 127435 | RNAseq | -0.7597 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 3.
Survival by PODN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PODN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PODN | 127435 | 3 | 4 | 23 | |
| GSE20123 | PODN | 127435 | 3 | 3 | 24 | |
| GSE43470 | PODN | 127435 | 6 | 2 | 35 | |
| GSE46452 | PODN | 127435 | 2 | 1 | 56 | |
| GSE47630 | PODN | 127435 | 8 | 4 | 28 | |
| GSE54993 | PODN | 127435 | 0 | 1 | 69 | |
| GSE54994 | PODN | 127435 | 11 | 2 | 40 | |
| GSE60625 | PODN | 127435 | 0 | 0 | 11 | |
| GSE74703 | PODN | 127435 | 4 | 1 | 31 | |
| GSE74704 | PODN | 127435 | 2 | 0 | 18 | |
| TCGA | PODN | 127435 | 10 | 18 | 68 |
Total number of gains: 49; Total number of losses: 36; Total Number of normals: 403.
Somatic mutations of PODN:
Generating mutation plots.
Highly correlated genes for PODN:
Showing top 20/805 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PODN | TNFSF12 | 0.784447 | 4 | 0 | 4 |
| PODN | SMOC2 | 0.77585 | 4 | 0 | 4 |
| PODN | C3orf70 | 0.775552 | 4 | 0 | 4 |
| PODN | COL8A1 | 0.773968 | 3 | 0 | 3 |
| PODN | TK2 | 0.771663 | 3 | 0 | 3 |
| PODN | GRHPR | 0.769299 | 3 | 0 | 3 |
| PODN | POLR2L | 0.767852 | 3 | 0 | 3 |
| PODN | ZNF347 | 0.7644 | 3 | 0 | 3 |
| PODN | RHOJ | 0.760075 | 4 | 0 | 4 |
| PODN | CYP21A2 | 0.758675 | 3 | 0 | 3 |
| PODN | RUNX1T1 | 0.758037 | 5 | 0 | 4 |
| PODN | DOCK1 | 0.75683 | 3 | 0 | 3 |
| PODN | TLN1 | 0.754716 | 3 | 0 | 3 |
| PODN | NKX6-1 | 0.75298 | 4 | 0 | 4 |
| PODN | TMEM47 | 0.752884 | 6 | 0 | 6 |
| PODN | CLEC3B | 0.752662 | 3 | 0 | 3 |
| PODN | ZEB1 | 0.751963 | 3 | 0 | 3 |
| PODN | CLU | 0.751446 | 4 | 0 | 4 |
| PODN | FOXF1 | 0.750898 | 6 | 0 | 6 |
| PODN | MEOX2 | 0.749791 | 5 | 0 | 4 |
For details and further investigation, click here
