| Full name: ATPase H+ transporting accessory protein 1 | Alias Symbol: ORF|XAP-3|VATPS1|16A|Ac45|XAP3|CF2 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 537 | HGNC ID: HGNC:868 | Ensembl Gene: ENSG00000071553 | OMIM ID: 300197 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
ATP6AP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05110 | Vibrio cholerae infection | |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | |
| hsa05152 | Tuberculosis | |
| hsa05161 | Hepatitis B |
Expression of ATP6AP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP6AP1 | 537 | 207809_s_at | -0.2629 | 0.5408 | |
| GSE20347 | ATP6AP1 | 537 | 207809_s_at | -0.6592 | 0.0000 | |
| GSE23400 | ATP6AP1 | 537 | 207809_s_at | -0.1965 | 0.0028 | |
| GSE26886 | ATP6AP1 | 537 | 207809_s_at | -0.4689 | 0.0279 | |
| GSE29001 | ATP6AP1 | 537 | 207809_s_at | -0.4240 | 0.0797 | |
| GSE38129 | ATP6AP1 | 537 | 207809_s_at | -0.2955 | 0.0566 | |
| GSE45670 | ATP6AP1 | 537 | 207809_s_at | -0.0081 | 0.9675 | |
| GSE53622 | ATP6AP1 | 537 | 42304 | -0.2525 | 0.0003 | |
| GSE53624 | ATP6AP1 | 537 | 42304 | -0.3012 | 0.0000 | |
| GSE63941 | ATP6AP1 | 537 | 207809_s_at | -0.0263 | 0.9599 | |
| GSE77861 | ATP6AP1 | 537 | 207809_s_at | -0.3832 | 0.1525 | |
| GSE97050 | ATP6AP1 | 537 | A_23_P250462 | -0.0300 | 0.9306 | |
| SRP007169 | ATP6AP1 | 537 | RNAseq | -1.6985 | 0.0002 | |
| SRP008496 | ATP6AP1 | 537 | RNAseq | -1.2636 | 0.0001 | |
| SRP064894 | ATP6AP1 | 537 | RNAseq | 0.3938 | 0.0076 | |
| SRP133303 | ATP6AP1 | 537 | RNAseq | 0.1436 | 0.3894 | |
| SRP159526 | ATP6AP1 | 537 | RNAseq | 0.1259 | 0.5860 | |
| SRP193095 | ATP6AP1 | 537 | RNAseq | -0.2127 | 0.0825 | |
| SRP219564 | ATP6AP1 | 537 | RNAseq | 0.1927 | 0.5314 | |
| TCGA | ATP6AP1 | 537 | RNAseq | 0.0204 | 0.6274 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ATP6AP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP6AP1:
No record found for this gene.
Somatic mutations of ATP6AP1:
Generating mutation plots.
Highly correlated genes for ATP6AP1:
Showing top 20/906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP6AP1 | TMEM139 | 0.741184 | 3 | 0 | 3 |
| ATP6AP1 | MYCN | 0.73692 | 3 | 0 | 3 |
| ATP6AP1 | TMEM54 | 0.728603 | 3 | 0 | 3 |
| ATP6AP1 | COMTD1 | 0.724698 | 4 | 0 | 3 |
| ATP6AP1 | SYTL1 | 0.72401 | 5 | 0 | 5 |
| ATP6AP1 | CCDC12 | 0.711366 | 3 | 0 | 3 |
| ATP6AP1 | DDX23 | 0.71057 | 3 | 0 | 3 |
| ATP6AP1 | PFKFB3 | 0.706815 | 3 | 0 | 3 |
| ATP6AP1 | FAM155A | 0.704879 | 3 | 0 | 3 |
| ATP6AP1 | CCDC97 | 0.699161 | 3 | 0 | 3 |
| ATP6AP1 | NDUFA10 | 0.698588 | 3 | 0 | 3 |
| ATP6AP1 | FZD4 | 0.698286 | 3 | 0 | 3 |
| ATP6AP1 | GTPBP1 | 0.695888 | 3 | 0 | 3 |
| ATP6AP1 | IRX3 | 0.693258 | 3 | 0 | 3 |
| ATP6AP1 | POLDIP3 | 0.691236 | 3 | 0 | 3 |
| ATP6AP1 | SLC35A4 | 0.687049 | 5 | 0 | 4 |
| ATP6AP1 | ERGIC3 | 0.684169 | 4 | 0 | 3 |
| ATP6AP1 | SLC30A9 | 0.683605 | 4 | 0 | 3 |
| ATP6AP1 | STK19 | 0.68116 | 6 | 0 | 4 |
| ATP6AP1 | FBXL16 | 0.681109 | 4 | 0 | 4 |
For details and further investigation, click here
