| Full name: RNA pseudouridine synthase D4 | Alias Symbol: FLJ14494 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 84881 | HGNC ID: HGNC:25898 | Ensembl Gene: ENSG00000165526 | OMIM ID: 617488 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPUSD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPUSD4 | 84881 | 225398_at | 0.1166 | 0.7796 | |
| GSE26886 | RPUSD4 | 84881 | 225398_at | -0.3052 | 0.0675 | |
| GSE45670 | RPUSD4 | 84881 | 225398_at | -0.1509 | 0.2462 | |
| GSE53622 | RPUSD4 | 84881 | 111605 | -0.1004 | 0.3075 | |
| GSE53624 | RPUSD4 | 84881 | 111605 | -0.0993 | 0.3976 | |
| GSE63941 | RPUSD4 | 84881 | 225398_at | -0.3018 | 0.3907 | |
| GSE77861 | RPUSD4 | 84881 | 225398_at | 0.0280 | 0.8868 | |
| GSE97050 | RPUSD4 | 84881 | A_24_P318073 | 0.1117 | 0.7288 | |
| SRP007169 | RPUSD4 | 84881 | RNAseq | -0.1784 | 0.7032 | |
| SRP008496 | RPUSD4 | 84881 | RNAseq | -0.3631 | 0.2286 | |
| SRP064894 | RPUSD4 | 84881 | RNAseq | -0.2323 | 0.1392 | |
| SRP133303 | RPUSD4 | 84881 | RNAseq | -0.3817 | 0.0024 | |
| SRP159526 | RPUSD4 | 84881 | RNAseq | -0.5004 | 0.1062 | |
| SRP193095 | RPUSD4 | 84881 | RNAseq | -0.5631 | 0.0000 | |
| SRP219564 | RPUSD4 | 84881 | RNAseq | -0.1084 | 0.7693 | |
| TCGA | RPUSD4 | 84881 | RNAseq | -0.1637 | 0.0323 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPUSD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPUSD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPUSD4 | 84881 | 0 | 13 | 17 | |
| GSE20123 | RPUSD4 | 84881 | 0 | 13 | 17 | |
| GSE43470 | RPUSD4 | 84881 | 2 | 7 | 34 | |
| GSE46452 | RPUSD4 | 84881 | 3 | 26 | 30 | |
| GSE47630 | RPUSD4 | 84881 | 2 | 19 | 19 | |
| GSE54993 | RPUSD4 | 84881 | 10 | 0 | 60 | |
| GSE54994 | RPUSD4 | 84881 | 5 | 19 | 29 | |
| GSE60625 | RPUSD4 | 84881 | 0 | 3 | 8 | |
| GSE74703 | RPUSD4 | 84881 | 1 | 5 | 30 | |
| GSE74704 | RPUSD4 | 84881 | 0 | 9 | 11 | |
| TCGA | RPUSD4 | 84881 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of RPUSD4:
Generating mutation plots.
Highly correlated genes for RPUSD4:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPUSD4 | RPS21 | 0.807555 | 3 | 0 | 3 |
| RPUSD4 | OXNAD1 | 0.766779 | 3 | 0 | 3 |
| RPUSD4 | PLEKHJ1 | 0.763549 | 3 | 0 | 3 |
| RPUSD4 | HNRNPAB | 0.757452 | 3 | 0 | 3 |
| RPUSD4 | TRAPPC4 | 0.74244 | 3 | 0 | 3 |
| RPUSD4 | MLLT10 | 0.738675 | 3 | 0 | 3 |
| RPUSD4 | UBE3C | 0.737165 | 3 | 0 | 3 |
| RPUSD4 | COG6 | 0.732459 | 3 | 0 | 3 |
| RPUSD4 | LZIC | 0.730839 | 3 | 0 | 3 |
| RPUSD4 | PWWP2A | 0.727853 | 3 | 0 | 3 |
| RPUSD4 | CCP110 | 0.721945 | 3 | 0 | 3 |
| RPUSD4 | APEH | 0.720578 | 3 | 0 | 3 |
| RPUSD4 | RMND1 | 0.715408 | 3 | 0 | 3 |
| RPUSD4 | CST7 | 0.714639 | 3 | 0 | 3 |
| RPUSD4 | KBTBD7 | 0.711786 | 3 | 0 | 3 |
| RPUSD4 | ABCD4 | 0.710292 | 3 | 0 | 3 |
| RPUSD4 | JTB | 0.709159 | 3 | 0 | 3 |
| RPUSD4 | MRPL39 | 0.706413 | 3 | 0 | 3 |
| RPUSD4 | DCTD | 0.704858 | 3 | 0 | 3 |
| RPUSD4 | ZNF23 | 0.704335 | 3 | 0 | 3 |
For details and further investigation, click here
