| Full name: nucleoporin 153 | Alias Symbol: HNUP153 | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 9972 | HGNC ID: HGNC:8062 | Ensembl Gene: ENSG00000124789 | OMIM ID: 603948 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP153:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP153 | 9972 | 202097_at | 0.4444 | 0.1587 | |
| GSE20347 | NUP153 | 9972 | 202097_at | 0.2383 | 0.2644 | |
| GSE23400 | NUP153 | 9972 | 202097_at | 0.5512 | 0.0000 | |
| GSE26886 | NUP153 | 9972 | 202097_at | -0.3892 | 0.0628 | |
| GSE29001 | NUP153 | 9972 | 202097_at | 0.4835 | 0.0295 | |
| GSE38129 | NUP153 | 9972 | 202097_at | 0.3483 | 0.0121 | |
| GSE45670 | NUP153 | 9972 | 202097_at | 0.0142 | 0.9393 | |
| GSE53622 | NUP153 | 9972 | 108588 | 0.0346 | 0.6892 | |
| GSE53624 | NUP153 | 9972 | 108588 | 0.2482 | 0.0000 | |
| GSE63941 | NUP153 | 9972 | 202097_at | 0.4623 | 0.1550 | |
| GSE77861 | NUP153 | 9972 | 202097_at | -0.0961 | 0.7900 | |
| GSE97050 | NUP153 | 9972 | A_33_P3306510 | 0.2737 | 0.3535 | |
| SRP007169 | NUP153 | 9972 | RNAseq | 0.7724 | 0.0204 | |
| SRP008496 | NUP153 | 9972 | RNAseq | 0.8517 | 0.0000 | |
| SRP064894 | NUP153 | 9972 | RNAseq | -0.2387 | 0.4218 | |
| SRP133303 | NUP153 | 9972 | RNAseq | 0.2567 | 0.0502 | |
| SRP159526 | NUP153 | 9972 | RNAseq | 0.2924 | 0.1793 | |
| SRP193095 | NUP153 | 9972 | RNAseq | 0.2305 | 0.0566 | |
| SRP219564 | NUP153 | 9972 | RNAseq | -0.1267 | 0.7221 | |
| TCGA | NUP153 | 9972 | RNAseq | 0.1158 | 0.0122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUP153 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP153:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP153 | 9972 | 2 | 5 | 23 | |
| GSE20123 | NUP153 | 9972 | 2 | 5 | 23 | |
| GSE43470 | NUP153 | 9972 | 9 | 0 | 34 | |
| GSE46452 | NUP153 | 9972 | 1 | 10 | 48 | |
| GSE47630 | NUP153 | 9972 | 7 | 7 | 26 | |
| GSE54993 | NUP153 | 9972 | 1 | 1 | 68 | |
| GSE54994 | NUP153 | 9972 | 10 | 3 | 40 | |
| GSE60625 | NUP153 | 9972 | 0 | 1 | 10 | |
| GSE74703 | NUP153 | 9972 | 8 | 0 | 28 | |
| GSE74704 | NUP153 | 9972 | 2 | 2 | 16 | |
| TCGA | NUP153 | 9972 | 16 | 26 | 54 |
Total number of gains: 58; Total number of losses: 60; Total Number of normals: 370.
Somatic mutations of NUP153:
Generating mutation plots.
Highly correlated genes for NUP153:
Showing top 20/701 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP153 | SLC25A19 | 0.811518 | 3 | 0 | 3 |
| NUP153 | C6orf136 | 0.780401 | 3 | 0 | 3 |
| NUP153 | TP53RK | 0.765089 | 3 | 0 | 3 |
| NUP153 | PIGU | 0.759561 | 3 | 0 | 3 |
| NUP153 | MDM2 | 0.758586 | 3 | 0 | 3 |
| NUP153 | ZNF700 | 0.736728 | 3 | 0 | 3 |
| NUP153 | FCHO1 | 0.734435 | 3 | 0 | 3 |
| NUP153 | ZNF234 | 0.730683 | 3 | 0 | 3 |
| NUP153 | TMEM209 | 0.727964 | 3 | 0 | 3 |
| NUP153 | CMTM4 | 0.719339 | 3 | 0 | 3 |
| NUP153 | ELK4 | 0.717217 | 4 | 0 | 3 |
| NUP153 | ISG20L2 | 0.716619 | 5 | 0 | 4 |
| NUP153 | NCOA6 | 0.712436 | 4 | 0 | 3 |
| NUP153 | THADA | 0.708954 | 4 | 0 | 3 |
| NUP153 | ZZZ3 | 0.707913 | 5 | 0 | 5 |
| NUP153 | TMEM237 | 0.696498 | 3 | 0 | 3 |
| NUP153 | TMCO6 | 0.696463 | 3 | 0 | 3 |
| NUP153 | ZNF668 | 0.693657 | 4 | 0 | 3 |
| NUP153 | RLIM | 0.693536 | 3 | 0 | 3 |
| NUP153 | TMEM117 | 0.690285 | 3 | 0 | 3 |
For details and further investigation, click here
