| Full name: zinc finger ZZ-type containing 3 | Alias Symbol: DKFZP564I052|ATAC1 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 26009 | HGNC ID: HGNC:24523 | Ensembl Gene: ENSG00000036549 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZZZ3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZZZ3 | 26009 | 212893_at | 0.2492 | 0.2471 | |
| GSE20347 | ZZZ3 | 26009 | 212893_at | 0.3045 | 0.0869 | |
| GSE23400 | ZZZ3 | 26009 | 212893_at | 0.5234 | 0.0000 | |
| GSE26886 | ZZZ3 | 26009 | 212893_at | 0.3084 | 0.3114 | |
| GSE29001 | ZZZ3 | 26009 | 212893_at | 0.4680 | 0.0777 | |
| GSE38129 | ZZZ3 | 26009 | 212893_at | 0.3847 | 0.0017 | |
| GSE45670 | ZZZ3 | 26009 | 212893_at | 0.2704 | 0.0460 | |
| GSE63941 | ZZZ3 | 26009 | 212893_at | -0.0972 | 0.8427 | |
| GSE77861 | ZZZ3 | 26009 | 212893_at | -0.0371 | 0.9200 | |
| GSE97050 | ZZZ3 | 26009 | A_23_P11507 | -0.0640 | 0.8236 | |
| SRP007169 | ZZZ3 | 26009 | RNAseq | 0.7255 | 0.0959 | |
| SRP008496 | ZZZ3 | 26009 | RNAseq | 0.5924 | 0.0044 | |
| SRP064894 | ZZZ3 | 26009 | RNAseq | 0.2883 | 0.1415 | |
| SRP133303 | ZZZ3 | 26009 | RNAseq | 0.1751 | 0.1355 | |
| SRP159526 | ZZZ3 | 26009 | RNAseq | -0.3486 | 0.1060 | |
| SRP193095 | ZZZ3 | 26009 | RNAseq | -0.0163 | 0.8560 | |
| SRP219564 | ZZZ3 | 26009 | RNAseq | 0.4645 | 0.2530 | |
| TCGA | ZZZ3 | 26009 | RNAseq | -0.0223 | 0.6493 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZZZ3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZZZ3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZZZ3 | 26009 | 0 | 7 | 23 | |
| GSE20123 | ZZZ3 | 26009 | 0 | 7 | 23 | |
| GSE43470 | ZZZ3 | 26009 | 3 | 3 | 37 | |
| GSE46452 | ZZZ3 | 26009 | 0 | 1 | 58 | |
| GSE47630 | ZZZ3 | 26009 | 8 | 6 | 26 | |
| GSE54993 | ZZZ3 | 26009 | 0 | 0 | 70 | |
| GSE54994 | ZZZ3 | 26009 | 6 | 3 | 44 | |
| GSE60625 | ZZZ3 | 26009 | 0 | 0 | 11 | |
| GSE74703 | ZZZ3 | 26009 | 2 | 3 | 31 | |
| GSE74704 | ZZZ3 | 26009 | 0 | 4 | 16 | |
| TCGA | ZZZ3 | 26009 | 8 | 24 | 64 |
Total number of gains: 27; Total number of losses: 58; Total Number of normals: 403.
Somatic mutations of ZZZ3:
Generating mutation plots.
Highly correlated genes for ZZZ3:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZZZ3 | DHX33 | 0.782347 | 3 | 0 | 3 |
| ZZZ3 | PPTC7 | 0.761193 | 3 | 0 | 3 |
| ZZZ3 | DCTN4 | 0.760915 | 3 | 0 | 3 |
| ZZZ3 | MED1 | 0.748696 | 3 | 0 | 3 |
| ZZZ3 | GZF1 | 0.740082 | 3 | 0 | 3 |
| ZZZ3 | PTCD2 | 0.734866 | 3 | 0 | 3 |
| ZZZ3 | LINC00328 | 0.729289 | 3 | 0 | 3 |
| ZZZ3 | DDX50 | 0.718839 | 5 | 0 | 5 |
| ZZZ3 | ZC3HC1 | 0.714064 | 3 | 0 | 3 |
| ZZZ3 | ZNF644 | 0.709795 | 7 | 0 | 7 |
| ZZZ3 | VPS8 | 0.708115 | 3 | 0 | 3 |
| ZZZ3 | NUP153 | 0.707913 | 5 | 0 | 5 |
| ZZZ3 | PDHX | 0.707355 | 4 | 0 | 3 |
| ZZZ3 | USP34 | 0.707056 | 3 | 0 | 3 |
| ZZZ3 | CBLL1 | 0.70646 | 3 | 0 | 3 |
| ZZZ3 | JKAMP | 0.703908 | 4 | 0 | 4 |
| ZZZ3 | STX16 | 0.701088 | 4 | 0 | 3 |
| ZZZ3 | RRM2B | 0.700072 | 3 | 0 | 3 |
| ZZZ3 | TRIM35 | 0.689066 | 3 | 0 | 3 |
| ZZZ3 | PLSCR4 | 0.68905 | 4 | 0 | 4 |
For details and further investigation, click here
