| Full name: FCH and mu domain containing endocytic adaptor 1 | Alias Symbol: KIAA0290 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 23149 | HGNC ID: HGNC:29002 | Ensembl Gene: ENSG00000130475 | OMIM ID: 613437 |
| Drug and gene relationship at DGIdb | |||
Expression of FCHO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCHO1 | 23149 | 213669_at | 0.3972 | 0.3283 | |
| GSE20347 | FCHO1 | 23149 | 213669_at | 0.1329 | 0.1104 | |
| GSE23400 | FCHO1 | 23149 | 213669_at | -0.0832 | 0.0603 | |
| GSE26886 | FCHO1 | 23149 | 213669_at | 0.5234 | 0.0002 | |
| GSE29001 | FCHO1 | 23149 | 213669_at | 0.2843 | 0.1339 | |
| GSE38129 | FCHO1 | 23149 | 213669_at | 0.2316 | 0.0128 | |
| GSE45670 | FCHO1 | 23149 | 213669_at | 0.2551 | 0.0293 | |
| GSE53622 | FCHO1 | 23149 | 8812 | 0.4511 | 0.0000 | |
| GSE53624 | FCHO1 | 23149 | 8812 | 0.4994 | 0.0002 | |
| GSE63941 | FCHO1 | 23149 | 213669_at | 0.1024 | 0.7212 | |
| GSE77861 | FCHO1 | 23149 | 213669_at | -0.1074 | 0.6147 | |
| GSE97050 | FCHO1 | 23149 | A_33_P3255509 | 0.1125 | 0.6923 | |
| SRP064894 | FCHO1 | 23149 | RNAseq | 0.7534 | 0.0146 | |
| SRP133303 | FCHO1 | 23149 | RNAseq | 0.2113 | 0.5495 | |
| SRP159526 | FCHO1 | 23149 | RNAseq | 0.0799 | 0.8842 | |
| SRP193095 | FCHO1 | 23149 | RNAseq | 1.0131 | 0.0004 | |
| SRP219564 | FCHO1 | 23149 | RNAseq | 0.4102 | 0.3360 | |
| TCGA | FCHO1 | 23149 | RNAseq | 0.8686 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FCHO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCHO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCHO1 | 23149 | 4 | 4 | 22 | |
| GSE20123 | FCHO1 | 23149 | 3 | 2 | 25 | |
| GSE43470 | FCHO1 | 23149 | 2 | 6 | 35 | |
| GSE46452 | FCHO1 | 23149 | 47 | 1 | 11 | |
| GSE47630 | FCHO1 | 23149 | 4 | 8 | 28 | |
| GSE54993 | FCHO1 | 23149 | 15 | 4 | 51 | |
| GSE54994 | FCHO1 | 23149 | 6 | 14 | 33 | |
| GSE60625 | FCHO1 | 23149 | 9 | 0 | 2 | |
| GSE74703 | FCHO1 | 23149 | 2 | 4 | 30 | |
| GSE74704 | FCHO1 | 23149 | 0 | 2 | 18 | |
| TCGA | FCHO1 | 23149 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of FCHO1:
Generating mutation plots.
Highly correlated genes for FCHO1:
Showing top 20/687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCHO1 | SSBP4 | 0.821997 | 3 | 0 | 3 |
| FCHO1 | CRTC2 | 0.808281 | 3 | 0 | 3 |
| FCHO1 | SNRPC | 0.792819 | 3 | 0 | 3 |
| FCHO1 | CXCR5 | 0.786685 | 3 | 0 | 3 |
| FCHO1 | LYRM4 | 0.786523 | 3 | 0 | 3 |
| FCHO1 | CSNK1G2 | 0.783877 | 4 | 0 | 4 |
| FCHO1 | STAT5A | 0.780312 | 3 | 0 | 3 |
| FCHO1 | ZNF358 | 0.77298 | 4 | 0 | 4 |
| FCHO1 | GAS6-AS1 | 0.772821 | 3 | 0 | 3 |
| FCHO1 | WDR81 | 0.770339 | 3 | 0 | 3 |
| FCHO1 | UBAP2L | 0.76756 | 3 | 0 | 3 |
| FCHO1 | CASKIN2 | 0.767219 | 3 | 0 | 3 |
| FCHO1 | MRPL55 | 0.762061 | 3 | 0 | 3 |
| FCHO1 | NKAPL | 0.752458 | 3 | 0 | 3 |
| FCHO1 | OR2T12 | 0.750028 | 3 | 0 | 3 |
| FCHO1 | NACC1 | 0.74858 | 4 | 0 | 4 |
| FCHO1 | EHMT2 | 0.747325 | 4 | 0 | 4 |
| FCHO1 | TEAD2 | 0.744388 | 4 | 0 | 4 |
| FCHO1 | FLYWCH2 | 0.739041 | 3 | 0 | 3 |
| FCHO1 | UAP1L1 | 0.738677 | 3 | 0 | 3 |
For details and further investigation, click here
