TMCO6

 

Full name: transmembrane and coiled-coil domains 6 Alias Symbol: FLJ39769|PRO1580
Type: protein-coding gene Cytoband: 5q31.3
Entrez ID: 55374 HGNC ID: HGNC:28814 Ensembl Gene: ENSG00000113119 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMCO6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMCO6 55374 221096_s_at 0.2650 0.4219
GSE20347 TMCO6 55374 221096_s_at 0.1636 0.2957
GSE23400 TMCO6 55374 221096_s_at 0.2679 0.0000
GSE26886 TMCO6 55374 221096_s_at -0.2272 0.2667
GSE29001 TMCO6 55374 221096_s_at 0.1385 0.5905
GSE38129 TMCO6 55374 221096_s_at 0.2946 0.0444
GSE45670 TMCO6 55374 221096_s_at 0.3614 0.0145
GSE63941 TMCO6 55374 221096_s_at 1.6408 0.0004
GSE77861 TMCO6 55374 221096_s_at 0.0041 0.9819
GSE97050 TMCO6 55374 A_23_P144639 0.2886 0.2839
SRP007169 TMCO6 55374 RNAseq -0.8205 0.1020
SRP008496 TMCO6 55374 RNAseq -0.3795 0.2670
SRP064894 TMCO6 55374 RNAseq 0.1787 0.3318
SRP133303 TMCO6 55374 RNAseq 0.2098 0.4386
SRP159526 TMCO6 55374 RNAseq -0.2128 0.3770
SRP193095 TMCO6 55374 RNAseq -0.1346 0.2174
SRP219564 TMCO6 55374 RNAseq 0.3430 0.5841
TCGA TMCO6 55374 RNAseq 0.2063 0.0039

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TMCO6 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of TMCO6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMCO6 55374 3 11 16
GSE20123 TMCO6 55374 4 11 15
GSE43470 TMCO6 55374 2 10 31
GSE46452 TMCO6 55374 0 27 32
GSE47630 TMCO6 55374 0 20 20
GSE54993 TMCO6 55374 9 1 60
GSE54994 TMCO6 55374 2 14 37
GSE60625 TMCO6 55374 0 0 11
GSE74703 TMCO6 55374 2 7 27
GSE74704 TMCO6 55374 3 5 12
TCGA TMCO6 55374 4 37 55

Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.  

 

Somatic mutations of TMCO6:

 

Generating mutation plots.

 

Highly correlated genes for TMCO6:

 

Showing top 20/463 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMCO6MRPL300.790388303
TMCO6GGN0.774329303
TMCO6PPP1R16A0.748414303
TMCO6MRPL380.748106303
TMCO6RSPRY10.748065303
TMCO6KIAA15220.74607404
TMCO6NSMCE20.742142303
TMCO6TBC1D40.729245303
TMCO6ROMO10.728975303
TMCO6DDX550.728778303
TMCO6IGSF60.727049303
TMCO6SOX70.723314303
TMCO6POLR2C0.719796303
TMCO6PRKCD0.717227303
TMCO6RAB1B0.717136303
TMCO6SELPLG0.715993303
TMCO6PRKAA10.712663303
TMCO6DAP30.710347303
TMCO6FKBPL0.704375303
TMCO6SYTL10.702159303

For details and further investigation, click here