| Full name: chromosome 6 open reading frame 136 | Alias Symbol: Em:AB023049.8 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 221545 | HGNC ID: HGNC:21301 | Ensembl Gene: ENSG00000204564 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C6orf136:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C6orf136 | 221545 | 227456_s_at | 0.2560 | 0.7682 | |
| GSE26886 | C6orf136 | 221545 | 227456_s_at | 0.3295 | 0.1544 | |
| GSE45670 | C6orf136 | 221545 | 227456_s_at | -0.0258 | 0.8518 | |
| GSE53622 | C6orf136 | 221545 | 49306 | -0.2975 | 0.0000 | |
| GSE53624 | C6orf136 | 221545 | 49306 | 0.0743 | 0.1860 | |
| GSE63941 | C6orf136 | 221545 | 227456_s_at | 0.3566 | 0.4852 | |
| GSE77861 | C6orf136 | 221545 | 227456_s_at | -0.2165 | 0.4101 | |
| GSE97050 | C6orf136 | 221545 | A_23_P300826 | 0.0407 | 0.8882 | |
| SRP007169 | C6orf136 | 221545 | RNAseq | -0.9961 | 0.0742 | |
| SRP008496 | C6orf136 | 221545 | RNAseq | -0.5860 | 0.1008 | |
| SRP064894 | C6orf136 | 221545 | RNAseq | 0.2043 | 0.4243 | |
| SRP133303 | C6orf136 | 221545 | RNAseq | -0.4190 | 0.0016 | |
| SRP159526 | C6orf136 | 221545 | RNAseq | 0.0150 | 0.9421 | |
| SRP193095 | C6orf136 | 221545 | RNAseq | -0.3134 | 0.0134 | |
| SRP219564 | C6orf136 | 221545 | RNAseq | 0.3000 | 0.4912 | |
| TCGA | C6orf136 | 221545 | RNAseq | -0.0593 | 0.3648 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C6orf136 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C6orf136:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C6orf136 | 221545 | 5 | 1 | 24 | |
| GSE20123 | C6orf136 | 221545 | 5 | 1 | 24 | |
| GSE43470 | C6orf136 | 221545 | 5 | 1 | 37 | |
| GSE46452 | C6orf136 | 221545 | 1 | 10 | 48 | |
| GSE47630 | C6orf136 | 221545 | 7 | 3 | 30 | |
| GSE54993 | C6orf136 | 221545 | 2 | 1 | 67 | |
| GSE54994 | C6orf136 | 221545 | 11 | 4 | 38 | |
| GSE60625 | C6orf136 | 221545 | 0 | 1 | 10 | |
| GSE74703 | C6orf136 | 221545 | 5 | 0 | 31 | |
| GSE74704 | C6orf136 | 221545 | 2 | 0 | 18 | |
| TCGA | C6orf136 | 221545 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of C6orf136:
Generating mutation plots.
Highly correlated genes for C6orf136:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C6orf136 | ABHD16A | 0.87264 | 3 | 0 | 3 |
| C6orf136 | ZNF502 | 0.835584 | 3 | 0 | 3 |
| C6orf136 | ZSCAN12 | 0.816236 | 3 | 0 | 3 |
| C6orf136 | ZNF506 | 0.787228 | 3 | 0 | 3 |
| C6orf136 | MEA1 | 0.786134 | 4 | 0 | 4 |
| C6orf136 | KCTD15 | 0.781688 | 3 | 0 | 3 |
| C6orf136 | NUP153 | 0.780401 | 3 | 0 | 3 |
| C6orf136 | PROSER1 | 0.780178 | 3 | 0 | 3 |
| C6orf136 | GPR143 | 0.761006 | 3 | 0 | 3 |
| C6orf136 | ZFAND3 | 0.758996 | 3 | 0 | 3 |
| C6orf136 | SYNGR3 | 0.756949 | 3 | 0 | 3 |
| C6orf136 | CAMTA1 | 0.755606 | 3 | 0 | 3 |
| C6orf136 | UROS | 0.750018 | 3 | 0 | 3 |
| C6orf136 | SLC25A19 | 0.741227 | 3 | 0 | 3 |
| C6orf136 | PIK3R3 | 0.738943 | 3 | 0 | 3 |
| C6orf136 | ANKRD17 | 0.730247 | 3 | 0 | 3 |
| C6orf136 | CNNM3 | 0.721195 | 3 | 0 | 3 |
| C6orf136 | PLXNB1 | 0.718389 | 4 | 0 | 3 |
| C6orf136 | SMARCC1 | 0.71765 | 4 | 0 | 4 |
| C6orf136 | EI24 | 0.717209 | 3 | 0 | 3 |
For details and further investigation, click here
