| Full name: CKLF like MARVEL transmembrane domain containing 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1-q22.3 | ||
| Entrez ID: 146223 | HGNC ID: HGNC:19175 | Ensembl Gene: ENSG00000183723 | OMIM ID: 607887 |
| Drug and gene relationship at DGIdb | |||
Expression of CMTM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMTM4 | 146223 | 225009_at | 0.9157 | 0.0494 | |
| GSE26886 | CMTM4 | 146223 | 224998_at | -0.3397 | 0.2079 | |
| GSE45670 | CMTM4 | 146223 | 224998_at | 0.3449 | 0.0298 | |
| GSE53622 | CMTM4 | 146223 | 57308 | 0.1184 | 0.3198 | |
| GSE53624 | CMTM4 | 146223 | 57308 | 0.2744 | 0.0300 | |
| GSE63941 | CMTM4 | 146223 | 225009_at | 4.1293 | 0.0000 | |
| GSE77861 | CMTM4 | 146223 | 225009_at | 0.6398 | 0.0197 | |
| GSE97050 | CMTM4 | 146223 | A_32_P84009 | 0.1088 | 0.6989 | |
| SRP007169 | CMTM4 | 146223 | RNAseq | 0.9604 | 0.0067 | |
| SRP008496 | CMTM4 | 146223 | RNAseq | 1.0516 | 0.0000 | |
| SRP064894 | CMTM4 | 146223 | RNAseq | 0.1732 | 0.3705 | |
| SRP133303 | CMTM4 | 146223 | RNAseq | 0.4851 | 0.0210 | |
| SRP159526 | CMTM4 | 146223 | RNAseq | 0.9401 | 0.0021 | |
| SRP193095 | CMTM4 | 146223 | RNAseq | -0.2352 | 0.3659 | |
| SRP219564 | CMTM4 | 146223 | RNAseq | 0.0770 | 0.8342 | |
| TCGA | CMTM4 | 146223 | RNAseq | -0.5879 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CMTM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CMTM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMTM4 | 146223 | 8 | 2 | 20 | |
| GSE20123 | CMTM4 | 146223 | 8 | 2 | 20 | |
| GSE43470 | CMTM4 | 146223 | 1 | 8 | 34 | |
| GSE46452 | CMTM4 | 146223 | 38 | 1 | 20 | |
| GSE47630 | CMTM4 | 146223 | 10 | 8 | 22 | |
| GSE54993 | CMTM4 | 146223 | 2 | 4 | 64 | |
| GSE54994 | CMTM4 | 146223 | 8 | 10 | 35 | |
| GSE60625 | CMTM4 | 146223 | 4 | 0 | 7 | |
| GSE74703 | CMTM4 | 146223 | 1 | 5 | 30 | |
| GSE74704 | CMTM4 | 146223 | 5 | 1 | 14 | |
| TCGA | CMTM4 | 146223 | 30 | 11 | 55 |
Total number of gains: 115; Total number of losses: 52; Total Number of normals: 321.
Somatic mutations of CMTM4:
Generating mutation plots.
Highly correlated genes for CMTM4:
Showing top 20/838 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMTM4 | TAF2 | 0.86735 | 3 | 0 | 3 |
| CMTM4 | SORL1 | 0.852293 | 3 | 0 | 3 |
| CMTM4 | SLC5A3 | 0.847672 | 3 | 0 | 3 |
| CMTM4 | IRX2 | 0.832882 | 3 | 0 | 3 |
| CMTM4 | MRPS30 | 0.821568 | 3 | 0 | 3 |
| CMTM4 | PTK2 | 0.820568 | 3 | 0 | 3 |
| CMTM4 | SLC39A10 | 0.820549 | 3 | 0 | 3 |
| CMTM4 | PMS1 | 0.814316 | 3 | 0 | 3 |
| CMTM4 | CNOT10 | 0.813093 | 3 | 0 | 3 |
| CMTM4 | METTL8 | 0.808192 | 3 | 0 | 3 |
| CMTM4 | TRIO | 0.792589 | 3 | 0 | 3 |
| CMTM4 | YWHAE | 0.791761 | 3 | 0 | 3 |
| CMTM4 | NEDD1 | 0.79003 | 3 | 0 | 3 |
| CMTM4 | LRP5 | 0.789696 | 4 | 0 | 4 |
| CMTM4 | FBXL6 | 0.789156 | 3 | 0 | 3 |
| CMTM4 | COCH | 0.781429 | 4 | 0 | 4 |
| CMTM4 | VAPB | 0.780242 | 3 | 0 | 3 |
| CMTM4 | STX16 | 0.775291 | 3 | 0 | 3 |
| CMTM4 | OSGEP | 0.77526 | 3 | 0 | 3 |
| CMTM4 | ARMC1 | 0.771934 | 3 | 0 | 3 |
For details and further investigation, click here
