| Full name: transmembrane protein 117 | Alias Symbol: DKFZp434K2435 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 84216 | HGNC ID: HGNC:25308 | Ensembl Gene: ENSG00000139173 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM117:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM117 | 84216 | 223594_at | 0.0260 | 0.9807 | |
| GSE26886 | TMEM117 | 84216 | 223594_at | -0.7846 | 0.0134 | |
| GSE45670 | TMEM117 | 84216 | 223594_at | 0.2920 | 0.0877 | |
| GSE53622 | TMEM117 | 84216 | 39105 | 0.1557 | 0.0279 | |
| GSE53624 | TMEM117 | 84216 | 39105 | -0.0077 | 0.9071 | |
| GSE63941 | TMEM117 | 84216 | 223594_at | -0.7973 | 0.2936 | |
| GSE77861 | TMEM117 | 84216 | 223594_at | 0.5968 | 0.2074 | |
| GSE97050 | TMEM117 | 84216 | A_23_P2573 | 0.2623 | 0.4305 | |
| SRP007169 | TMEM117 | 84216 | RNAseq | -0.1211 | 0.8185 | |
| SRP008496 | TMEM117 | 84216 | RNAseq | -0.2165 | 0.4728 | |
| SRP064894 | TMEM117 | 84216 | RNAseq | -0.3991 | 0.0298 | |
| SRP133303 | TMEM117 | 84216 | RNAseq | -0.0063 | 0.9821 | |
| SRP159526 | TMEM117 | 84216 | RNAseq | 0.0515 | 0.8713 | |
| SRP193095 | TMEM117 | 84216 | RNAseq | -0.3756 | 0.0143 | |
| SRP219564 | TMEM117 | 84216 | RNAseq | -0.7183 | 0.0176 | |
| TCGA | TMEM117 | 84216 | RNAseq | 0.2326 | 0.0045 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM117 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM117:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM117 | 84216 | 5 | 1 | 24 | |
| GSE20123 | TMEM117 | 84216 | 5 | 1 | 24 | |
| GSE43470 | TMEM117 | 84216 | 3 | 3 | 37 | |
| GSE46452 | TMEM117 | 84216 | 8 | 1 | 50 | |
| GSE47630 | TMEM117 | 84216 | 11 | 2 | 27 | |
| GSE54993 | TMEM117 | 84216 | 0 | 6 | 64 | |
| GSE54994 | TMEM117 | 84216 | 7 | 1 | 45 | |
| GSE60625 | TMEM117 | 84216 | 0 | 0 | 11 | |
| GSE74703 | TMEM117 | 84216 | 3 | 2 | 31 | |
| GSE74704 | TMEM117 | 84216 | 3 | 1 | 16 | |
| TCGA | TMEM117 | 84216 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 34; Total Number of normals: 394.
Somatic mutations of TMEM117:
Generating mutation plots.
Highly correlated genes for TMEM117:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM117 | MFN1 | 0.81253 | 3 | 0 | 3 |
| TMEM117 | ALG14 | 0.780609 | 3 | 0 | 3 |
| TMEM117 | NCBP1 | 0.777009 | 3 | 0 | 3 |
| TMEM117 | PPIP5K2 | 0.770211 | 3 | 0 | 3 |
| TMEM117 | PGM3 | 0.757482 | 3 | 0 | 3 |
| TMEM117 | FBXO33 | 0.756945 | 3 | 0 | 3 |
| TMEM117 | WDFY1 | 0.755673 | 3 | 0 | 3 |
| TMEM117 | YLPM1 | 0.755382 | 3 | 0 | 3 |
| TMEM117 | PSMD1 | 0.754438 | 3 | 0 | 3 |
| TMEM117 | TNKS2 | 0.75248 | 3 | 0 | 3 |
| TMEM117 | JKAMP | 0.751174 | 3 | 0 | 3 |
| TMEM117 | MGAT2 | 0.750806 | 3 | 0 | 3 |
| TMEM117 | GINS3 | 0.747796 | 3 | 0 | 3 |
| TMEM117 | AHCYL2 | 0.746214 | 3 | 0 | 3 |
| TMEM117 | SLC12A6 | 0.745487 | 3 | 0 | 3 |
| TMEM117 | STAM | 0.745331 | 3 | 0 | 3 |
| TMEM117 | APEH | 0.744055 | 3 | 0 | 3 |
| TMEM117 | MPP5 | 0.742795 | 3 | 0 | 3 |
| TMEM117 | AASDHPPT | 0.741697 | 3 | 0 | 3 |
| TMEM117 | PI4K2A | 0.73313 | 3 | 0 | 3 |
For details and further investigation, click here
