| Full name: nucleoredoxin like 2 | Alias Symbol: RdCVF2 | ||
| Type: protein-coding gene | Cytoband: 9q22.1 | ||
| Entrez ID: 158046 | HGNC ID: HGNC:30482 | Ensembl Gene: ENSG00000130045 | OMIM ID: 615299 |
| Drug and gene relationship at DGIdb | |||
Expression of NXNL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXNL2 | 158046 | 1552816_at | -0.0475 | 0.8765 | |
| GSE26886 | NXNL2 | 158046 | 1552816_at | 0.0243 | 0.7924 | |
| GSE45670 | NXNL2 | 158046 | 1552816_at | -0.0331 | 0.7237 | |
| GSE53622 | NXNL2 | 158046 | 32111 | 0.2103 | 0.0011 | |
| GSE53624 | NXNL2 | 158046 | 32111 | 0.2116 | 0.0001 | |
| GSE63941 | NXNL2 | 158046 | 1552816_at | -0.1359 | 0.2062 | |
| GSE77861 | NXNL2 | 158046 | 1552816_at | -0.0011 | 0.9929 | |
| GSE97050 | NXNL2 | 158046 | A_33_P3400828 | -0.0041 | 0.9924 | |
| SRP064894 | NXNL2 | 158046 | RNAseq | -0.8598 | 0.0002 | |
| SRP133303 | NXNL2 | 158046 | RNAseq | 0.0125 | 0.9275 | |
| SRP159526 | NXNL2 | 158046 | RNAseq | -0.3901 | 0.2977 | |
| SRP193095 | NXNL2 | 158046 | RNAseq | 0.2024 | 0.1187 | |
| SRP219564 | NXNL2 | 158046 | RNAseq | -1.1469 | 0.0073 | |
| TCGA | NXNL2 | 158046 | RNAseq | -0.0019 | 0.9978 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NXNL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NXNL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXNL2 | 158046 | 5 | 10 | 15 | |
| GSE20123 | NXNL2 | 158046 | 5 | 10 | 15 | |
| GSE43470 | NXNL2 | 158046 | 6 | 3 | 34 | |
| GSE46452 | NXNL2 | 158046 | 6 | 14 | 39 | |
| GSE47630 | NXNL2 | 158046 | 1 | 18 | 21 | |
| GSE54993 | NXNL2 | 158046 | 4 | 2 | 64 | |
| GSE54994 | NXNL2 | 158046 | 6 | 11 | 36 | |
| GSE60625 | NXNL2 | 158046 | 0 | 0 | 11 | |
| GSE74703 | NXNL2 | 158046 | 5 | 3 | 28 | |
| GSE74704 | NXNL2 | 158046 | 3 | 7 | 10 | |
| TCGA | NXNL2 | 158046 | 20 | 25 | 51 |
Total number of gains: 61; Total number of losses: 103; Total Number of normals: 324.
Somatic mutations of NXNL2:
Generating mutation plots.
Highly correlated genes for NXNL2:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXNL2 | AMH | 0.739684 | 3 | 0 | 3 |
| NXNL2 | RNF139 | 0.737292 | 3 | 0 | 3 |
| NXNL2 | HSPA5 | 0.731454 | 3 | 0 | 3 |
| NXNL2 | ING2 | 0.706297 | 3 | 0 | 3 |
| NXNL2 | SLC26A5 | 0.701582 | 3 | 0 | 3 |
| NXNL2 | HABP4 | 0.689614 | 3 | 0 | 3 |
| NXNL2 | ZNF584 | 0.676772 | 3 | 0 | 3 |
| NXNL2 | SLC13A2 | 0.67386 | 3 | 0 | 3 |
| NXNL2 | MRPS25 | 0.673536 | 3 | 0 | 3 |
| NXNL2 | PRR23C | 0.671583 | 3 | 0 | 3 |
| NXNL2 | KRTAP12-2 | 0.663787 | 3 | 0 | 3 |
| NXNL2 | NRSN2 | 0.662701 | 3 | 0 | 3 |
| NXNL2 | TTC14 | 0.662177 | 3 | 0 | 3 |
| NXNL2 | RBM17 | 0.661208 | 3 | 0 | 3 |
| NXNL2 | SLC25A29 | 0.657359 | 4 | 0 | 3 |
| NXNL2 | PLXNB3 | 0.657134 | 3 | 0 | 3 |
| NXNL2 | CD36 | 0.655766 | 3 | 0 | 3 |
| NXNL2 | TMEM63B | 0.652323 | 4 | 0 | 3 |
| NXNL2 | OR1L6 | 0.64899 | 3 | 0 | 3 |
| NXNL2 | ZBTB10 | 0.638266 | 3 | 0 | 3 |
For details and further investigation, click here
