| Full name: inhibitor of growth family member 2 | Alias Symbol: p33ING2 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 3622 | HGNC ID: HGNC:6063 | Ensembl Gene: ENSG00000168556 | OMIM ID: 604215 |
| Drug and gene relationship at DGIdb | |||
Expression of ING2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ING2 | 3622 | 205981_s_at | -0.6563 | 0.2297 | |
| GSE20347 | ING2 | 3622 | 205981_s_at | -0.5608 | 0.0014 | |
| GSE23400 | ING2 | 3622 | 205981_s_at | -0.2053 | 0.0193 | |
| GSE26886 | ING2 | 3622 | 205981_s_at | 0.4618 | 0.0623 | |
| GSE29001 | ING2 | 3622 | 205981_s_at | -0.2442 | 0.7115 | |
| GSE38129 | ING2 | 3622 | 205981_s_at | -0.5037 | 0.0051 | |
| GSE45670 | ING2 | 3622 | 205981_s_at | -0.4098 | 0.0215 | |
| GSE53622 | ING2 | 3622 | 100061 | -0.5049 | 0.0000 | |
| GSE53624 | ING2 | 3622 | 100061 | -0.4610 | 0.0000 | |
| GSE63941 | ING2 | 3622 | 205981_s_at | -0.4023 | 0.5176 | |
| GSE77861 | ING2 | 3622 | 205981_s_at | 0.0396 | 0.9377 | |
| GSE97050 | ING2 | 3622 | A_23_P83736 | -0.5944 | 0.1695 | |
| SRP007169 | ING2 | 3622 | RNAseq | -0.5148 | 0.2225 | |
| SRP008496 | ING2 | 3622 | RNAseq | -0.5467 | 0.1376 | |
| SRP064894 | ING2 | 3622 | RNAseq | -0.2419 | 0.3051 | |
| SRP133303 | ING2 | 3622 | RNAseq | 0.2692 | 0.2179 | |
| SRP159526 | ING2 | 3622 | RNAseq | -0.4914 | 0.1095 | |
| SRP193095 | ING2 | 3622 | RNAseq | -0.2990 | 0.0491 | |
| SRP219564 | ING2 | 3622 | RNAseq | -0.3189 | 0.3485 | |
| TCGA | ING2 | 3622 | RNAseq | -0.0205 | 0.7583 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ING2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ING2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ING2 | 3622 | 2 | 11 | 17 | |
| GSE20123 | ING2 | 3622 | 2 | 11 | 17 | |
| GSE43470 | ING2 | 3622 | 0 | 12 | 31 | |
| GSE46452 | ING2 | 3622 | 1 | 36 | 22 | |
| GSE47630 | ING2 | 3622 | 0 | 22 | 18 | |
| GSE54993 | ING2 | 3622 | 10 | 0 | 60 | |
| GSE54994 | ING2 | 3622 | 2 | 12 | 39 | |
| GSE60625 | ING2 | 3622 | 0 | 0 | 11 | |
| GSE74703 | ING2 | 3622 | 0 | 9 | 27 | |
| GSE74704 | ING2 | 3622 | 1 | 5 | 14 | |
| TCGA | ING2 | 3622 | 11 | 32 | 53 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of ING2:
Generating mutation plots.
Highly correlated genes for ING2:
Showing top 20/551 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ING2 | CDC73 | 0.831379 | 3 | 0 | 3 |
| ING2 | BUD31 | 0.790347 | 3 | 0 | 3 |
| ING2 | TAF7 | 0.773157 | 4 | 0 | 4 |
| ING2 | CIR1 | 0.759147 | 3 | 0 | 3 |
| ING2 | POLR3C | 0.748442 | 3 | 0 | 3 |
| ING2 | STK40 | 0.745822 | 3 | 0 | 3 |
| ING2 | SH3YL1 | 0.740786 | 3 | 0 | 3 |
| ING2 | HIF1A | 0.724315 | 3 | 0 | 3 |
| ING2 | HSPA9 | 0.723999 | 3 | 0 | 3 |
| ING2 | ZNF766 | 0.720848 | 3 | 0 | 3 |
| ING2 | NXNL2 | 0.706297 | 3 | 0 | 3 |
| ING2 | RMDN1 | 0.705103 | 3 | 0 | 3 |
| ING2 | FAM76A | 0.702776 | 3 | 0 | 3 |
| ING2 | ZBTB11 | 0.702552 | 3 | 0 | 3 |
| ING2 | HDAC3 | 0.700555 | 4 | 0 | 3 |
| ING2 | SARNP | 0.699668 | 3 | 0 | 3 |
| ING2 | PITHD1 | 0.697926 | 4 | 0 | 4 |
| ING2 | SCAF11 | 0.691336 | 4 | 0 | 3 |
| ING2 | VCPKMT | 0.687658 | 3 | 0 | 3 |
| ING2 | SMU1 | 0.685857 | 5 | 0 | 4 |
For details and further investigation, click here
