| Full name: CD36 molecule | Alias Symbol: SCARB3|GPIV|FAT|GP4|GP3B | ||
| Type: protein-coding gene | Cytoband: 7q21.11 | ||
| Entrez ID: 948 | HGNC ID: HGNC:1663 | Ensembl Gene: ENSG00000135218 | OMIM ID: 173510 |
| Drug and gene relationship at DGIdb | |||
CD36 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway | |
| hsa04152 | AMPK signaling pathway | |
| hsa04920 | Adipocytokine signaling pathway |
Expression of CD36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD36 | 948 | 206488_s_at | 0.2633 | 0.8624 | |
| GSE20347 | CD36 | 948 | 209555_s_at | 0.4448 | 0.3932 | |
| GSE23400 | CD36 | 948 | 209555_s_at | 0.0493 | 0.7289 | |
| GSE26886 | CD36 | 948 | 206488_s_at | -0.0606 | 0.8714 | |
| GSE29001 | CD36 | 948 | 209555_s_at | -0.0638 | 0.9474 | |
| GSE38129 | CD36 | 948 | 209555_s_at | -0.2785 | 0.6572 | |
| GSE45670 | CD36 | 948 | 209555_s_at | 0.1360 | 0.8766 | |
| GSE53622 | CD36 | 948 | 18563 | -0.6929 | 0.0004 | |
| GSE53624 | CD36 | 948 | 18563 | -0.5478 | 0.0002 | |
| GSE63941 | CD36 | 948 | 206488_s_at | 0.5294 | 0.6823 | |
| GSE77861 | CD36 | 948 | 209554_at | 0.0096 | 0.9534 | |
| GSE97050 | CD36 | 948 | A_23_P111583 | -0.0346 | 0.9371 | |
| SRP007169 | CD36 | 948 | RNAseq | 1.4261 | 0.1551 | |
| SRP008496 | CD36 | 948 | RNAseq | 0.7413 | 0.3931 | |
| SRP064894 | CD36 | 948 | RNAseq | 1.0955 | 0.0228 | |
| SRP133303 | CD36 | 948 | RNAseq | -0.3385 | 0.4165 | |
| SRP159526 | CD36 | 948 | RNAseq | 0.5254 | 0.4926 | |
| SRP193095 | CD36 | 948 | RNAseq | -0.5773 | 0.1053 | |
| SRP219564 | CD36 | 948 | RNAseq | 1.1868 | 0.2405 | |
| TCGA | CD36 | 948 | RNAseq | -0.6247 | 0.0016 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CD36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD36 | 948 | 13 | 1 | 16 | |
| GSE20123 | CD36 | 948 | 12 | 1 | 17 | |
| GSE43470 | CD36 | 948 | 4 | 1 | 38 | |
| GSE46452 | CD36 | 948 | 11 | 0 | 48 | |
| GSE47630 | CD36 | 948 | 7 | 3 | 30 | |
| GSE54993 | CD36 | 948 | 1 | 7 | 62 | |
| GSE54994 | CD36 | 948 | 16 | 3 | 34 | |
| GSE60625 | CD36 | 948 | 0 | 0 | 11 | |
| GSE74703 | CD36 | 948 | 3 | 1 | 32 | |
| GSE74704 | CD36 | 948 | 8 | 1 | 11 | |
| TCGA | CD36 | 948 | 46 | 5 | 45 |
Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.
Somatic mutations of CD36:
Generating mutation plots.
Highly correlated genes for CD36:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD36 | KLRC3 | 0.780473 | 3 | 0 | 3 |
| CD36 | TCL1B | 0.752165 | 3 | 0 | 3 |
| CD36 | PSME1 | 0.72348 | 3 | 0 | 3 |
| CD36 | RASSF8 | 0.722209 | 3 | 0 | 3 |
| CD36 | DNAH11 | 0.716697 | 3 | 0 | 3 |
| CD36 | TPSG1 | 0.714243 | 3 | 0 | 3 |
| CD36 | NFE4 | 0.70361 | 3 | 0 | 3 |
| CD36 | FGFRL1 | 0.703542 | 3 | 0 | 3 |
| CD36 | MAPK9 | 0.699902 | 3 | 0 | 3 |
| CD36 | RNF183 | 0.684342 | 3 | 0 | 3 |
| CD36 | GPR161 | 0.675135 | 3 | 0 | 3 |
| CD36 | SNCA | 0.674431 | 3 | 0 | 3 |
| CD36 | KLF11 | 0.661484 | 3 | 0 | 3 |
| CD36 | KLF7 | 0.661146 | 3 | 0 | 3 |
| CD36 | TNFRSF8 | 0.660708 | 4 | 0 | 3 |
| CD36 | TMOD1 | 0.658885 | 3 | 0 | 3 |
| CD36 | NXNL2 | 0.655766 | 3 | 0 | 3 |
| CD36 | ACY1 | 0.65293 | 3 | 0 | 3 |
| CD36 | MPPED2 | 0.652472 | 3 | 0 | 3 |
| CD36 | COL8A2 | 0.652272 | 3 | 0 | 3 |
For details and further investigation, click here
