| Full name: solute carrier family 13 member 2 | Alias Symbol: NaDC-1 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 9058 | HGNC ID: HGNC:10917 | Ensembl Gene: ENSG00000007216 | OMIM ID: 604148 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SLC13A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC13A2 | 9058 | 207567_at | -0.0145 | 0.9761 | |
| GSE20347 | SLC13A2 | 9058 | 207567_at | -0.1227 | 0.1127 | |
| GSE23400 | SLC13A2 | 9058 | 207567_at | -0.1441 | 0.0006 | |
| GSE26886 | SLC13A2 | 9058 | 207567_at | -0.0066 | 0.9516 | |
| GSE29001 | SLC13A2 | 9058 | 207567_at | -0.1860 | 0.2721 | |
| GSE38129 | SLC13A2 | 9058 | 207567_at | -0.1487 | 0.0170 | |
| GSE45670 | SLC13A2 | 9058 | 207567_at | -0.0529 | 0.5482 | |
| GSE53622 | SLC13A2 | 9058 | 13265 | -0.0189 | 0.8515 | |
| GSE53624 | SLC13A2 | 9058 | 13265 | 0.0993 | 0.2642 | |
| GSE63941 | SLC13A2 | 9058 | 207567_at | 0.0988 | 0.5430 | |
| GSE77861 | SLC13A2 | 9058 | 207567_at | -0.0865 | 0.4332 | |
| GSE97050 | SLC13A2 | 9058 | A_23_P107307 | -0.1726 | 0.4079 | |
| TCGA | SLC13A2 | 9058 | RNAseq | 0.3010 | 0.7518 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC13A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC13A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC13A2 | 9058 | 9 | 1 | 20 | |
| GSE20123 | SLC13A2 | 9058 | 9 | 1 | 20 | |
| GSE43470 | SLC13A2 | 9058 | 0 | 1 | 42 | |
| GSE46452 | SLC13A2 | 9058 | 33 | 1 | 25 | |
| GSE47630 | SLC13A2 | 9058 | 7 | 1 | 32 | |
| GSE54993 | SLC13A2 | 9058 | 2 | 3 | 65 | |
| GSE54994 | SLC13A2 | 9058 | 7 | 6 | 40 | |
| GSE60625 | SLC13A2 | 9058 | 4 | 0 | 7 | |
| GSE74703 | SLC13A2 | 9058 | 0 | 1 | 35 | |
| GSE74704 | SLC13A2 | 9058 | 7 | 1 | 12 | |
| TCGA | SLC13A2 | 9058 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of SLC13A2:
Generating mutation plots.
Highly correlated genes for SLC13A2:
Showing top 20/653 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC13A2 | LIPF | 0.813388 | 3 | 0 | 3 |
| SLC13A2 | DHDH | 0.811232 | 3 | 0 | 3 |
| SLC13A2 | ZNF358 | 0.808636 | 3 | 0 | 3 |
| SLC13A2 | KRTAP19-2 | 0.798107 | 3 | 0 | 3 |
| SLC13A2 | SREBF2 | 0.762724 | 3 | 0 | 3 |
| SLC13A2 | CCNB3 | 0.754573 | 3 | 0 | 3 |
| SLC13A2 | AP1B1 | 0.753921 | 3 | 0 | 3 |
| SLC13A2 | ZNF416 | 0.744995 | 3 | 0 | 3 |
| SLC13A2 | DENND5B | 0.740541 | 3 | 0 | 3 |
| SLC13A2 | ELFN1 | 0.736745 | 4 | 0 | 4 |
| SLC13A2 | RABEP2 | 0.731351 | 4 | 0 | 3 |
| SLC13A2 | TAF1L | 0.728628 | 3 | 0 | 3 |
| SLC13A2 | HES6 | 0.727926 | 3 | 0 | 3 |
| SLC13A2 | ABHD14B | 0.726375 | 3 | 0 | 3 |
| SLC13A2 | AMH | 0.722809 | 3 | 0 | 3 |
| SLC13A2 | KIR3DL2 | 0.719872 | 3 | 0 | 3 |
| SLC13A2 | ZNF547 | 0.712817 | 3 | 0 | 3 |
| SLC13A2 | HEMK1 | 0.711294 | 3 | 0 | 3 |
| SLC13A2 | ZNF735 | 0.706797 | 3 | 0 | 3 |
| SLC13A2 | C12orf50 | 0.702153 | 4 | 0 | 3 |
For details and further investigation, click here
