| Full name: tetratricopeptide repeat domain 14 | Alias Symbol: FLJ00166|KIAA1980 | ||
| Type: protein-coding gene | Cytoband: 3q26.33 | ||
| Entrez ID: 151613 | HGNC ID: HGNC:24697 | Ensembl Gene: ENSG00000163728 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC14 | 151613 | 225180_at | 0.0239 | 0.9630 | |
| GSE26886 | TTC14 | 151613 | 225180_at | -0.2060 | 0.6770 | |
| GSE45670 | TTC14 | 151613 | 225180_at | 0.3304 | 0.1164 | |
| GSE53622 | TTC14 | 151613 | 30102 | 0.4697 | 0.0000 | |
| GSE53624 | TTC14 | 151613 | 30102 | 0.3560 | 0.0000 | |
| GSE63941 | TTC14 | 151613 | 225180_at | -0.1347 | 0.8096 | |
| GSE77861 | TTC14 | 151613 | 225180_at | 0.3558 | 0.3925 | |
| GSE97050 | TTC14 | 151613 | A_23_P212511 | 0.2493 | 0.3935 | |
| SRP007169 | TTC14 | 151613 | RNAseq | 1.0902 | 0.0875 | |
| SRP008496 | TTC14 | 151613 | RNAseq | 1.3346 | 0.0019 | |
| SRP064894 | TTC14 | 151613 | RNAseq | 0.3356 | 0.1178 | |
| SRP133303 | TTC14 | 151613 | RNAseq | 0.1992 | 0.1213 | |
| SRP159526 | TTC14 | 151613 | RNAseq | 0.3569 | 0.3054 | |
| SRP193095 | TTC14 | 151613 | RNAseq | 0.2926 | 0.0090 | |
| SRP219564 | TTC14 | 151613 | RNAseq | 0.0652 | 0.8590 | |
| TCGA | TTC14 | 151613 | RNAseq | -0.0601 | 0.3573 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TTC14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC14 | 151613 | 25 | 0 | 5 | |
| GSE20123 | TTC14 | 151613 | 25 | 0 | 5 | |
| GSE43470 | TTC14 | 151613 | 24 | 0 | 19 | |
| GSE46452 | TTC14 | 151613 | 19 | 1 | 39 | |
| GSE47630 | TTC14 | 151613 | 27 | 2 | 11 | |
| GSE54993 | TTC14 | 151613 | 1 | 18 | 51 | |
| GSE54994 | TTC14 | 151613 | 41 | 0 | 12 | |
| GSE60625 | TTC14 | 151613 | 0 | 6 | 5 | |
| GSE74703 | TTC14 | 151613 | 20 | 0 | 16 | |
| GSE74704 | TTC14 | 151613 | 16 | 0 | 4 | |
| TCGA | TTC14 | 151613 | 78 | 0 | 18 |
Total number of gains: 276; Total number of losses: 27; Total Number of normals: 185.
Somatic mutations of TTC14:
Generating mutation plots.
Highly correlated genes for TTC14:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC14 | METTL14 | 0.7879 | 3 | 0 | 3 |
| TTC14 | BSDC1 | 0.760959 | 3 | 0 | 3 |
| TTC14 | SCAF8 | 0.757346 | 3 | 0 | 3 |
| TTC14 | THUMPD2 | 0.739828 | 3 | 0 | 3 |
| TTC14 | JTB | 0.739823 | 3 | 0 | 3 |
| TTC14 | YTHDF3 | 0.737419 | 3 | 0 | 3 |
| TTC14 | CHIC1 | 0.7295 | 3 | 0 | 3 |
| TTC14 | UBR3 | 0.725939 | 3 | 0 | 3 |
| TTC14 | ZNF564 | 0.722797 | 3 | 0 | 3 |
| TTC14 | SIPA1L2 | 0.721681 | 4 | 0 | 4 |
| TTC14 | KCTD18 | 0.719998 | 3 | 0 | 3 |
| TTC14 | DEGS1 | 0.719202 | 3 | 0 | 3 |
| TTC14 | C11orf58 | 0.713323 | 3 | 0 | 3 |
| TTC14 | GGNBP2 | 0.702171 | 4 | 0 | 4 |
| TTC14 | PPIG | 0.702134 | 3 | 0 | 3 |
| TTC14 | MYLIP | 0.700596 | 3 | 0 | 3 |
| TTC14 | GFM2 | 0.692846 | 3 | 0 | 3 |
| TTC14 | ATXN2 | 0.692291 | 3 | 0 | 3 |
| TTC14 | PIP4K2B | 0.692277 | 3 | 0 | 3 |
| TTC14 | ANAPC4 | 0.691184 | 3 | 0 | 3 |
For details and further investigation, click here
