RNF139

 

Full name: ring finger protein 139 Alias Symbol: TRC8|RCA1|HRCA1
Type: protein-coding gene Cytoband: 8q24.13
Entrez ID: 11236 HGNC ID: HGNC:17023 Ensembl Gene: ENSG00000170881 OMIM ID: 603046
Drug and gene relationship at DGIdb

 

Expression of RNF139:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF139 11236 209510_at 0.2893 0.5041
GSE20347 RNF139 11236 209510_at 0.2222 0.1695
GSE23400 RNF139 11236 209510_at 0.3009 0.0001
GSE26886 RNF139 11236 209510_at 0.0795 0.7596
GSE29001 RNF139 11236 209510_at 0.2613 0.3642
GSE38129 RNF139 11236 209510_at 0.1539 0.1614
GSE45670 RNF139 11236 209510_at 0.0368 0.8423
GSE53622 RNF139 11236 80106 0.0491 0.4940
GSE53624 RNF139 11236 80106 0.2125 0.0007
GSE63941 RNF139 11236 209510_at 0.0487 0.9401
GSE77861 RNF139 11236 209510_at 0.1346 0.5416
GSE97050 RNF139 11236 A_23_P146765 0.1091 0.7333
SRP007169 RNF139 11236 RNAseq -0.5077 0.1258
SRP008496 RNF139 11236 RNAseq -0.0710 0.7262
SRP064894 RNF139 11236 RNAseq 0.2196 0.1593
SRP133303 RNF139 11236 RNAseq 0.3399 0.0068
SRP159526 RNF139 11236 RNAseq -0.1456 0.5177
SRP193095 RNF139 11236 RNAseq 0.0166 0.9071
SRP219564 RNF139 11236 RNAseq -0.0715 0.7736
TCGA RNF139 11236 RNAseq 0.1012 0.0464

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RNF139 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RNF139:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF139 11236 19 0 11
GSE20123 RNF139 11236 20 0 10
GSE43470 RNF139 11236 22 0 21
GSE46452 RNF139 11236 28 0 31
GSE47630 RNF139 11236 24 0 16
GSE54993 RNF139 11236 0 21 49
GSE54994 RNF139 11236 36 1 16
GSE60625 RNF139 11236 0 4 7
GSE74703 RNF139 11236 19 0 17
GSE74704 RNF139 11236 13 0 7
TCGA RNF139 11236 68 1 27

Total number of gains: 249; Total number of losses: 27; Total Number of normals: 212.  

 

Somatic mutations of RNF139:

 

Generating mutation plots.

 

Highly correlated genes for RNF139:

 

Showing top 20/528 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF139PPTC70.772441303
RNF139NMT10.76492303
RNF139ASB20.761644303
RNF139NOSIP0.760139303
RNF139MBTPS10.748541303
RNF139AURKAIP10.744524303
RNF139NXNL20.737292303
RNF139CHIC10.737069303
RNF139ARID1A0.73493303
RNF139CEBPZ0.734897404
RNF139GTPBP60.729468303
RNF139TTC370.727304303
RNF139TMEM2050.724531404
RNF139UBTD20.714681404
RNF139NSA20.713061303
RNF139ITPR10.712943303
RNF139CHMP1B0.710823303
RNF139LIPT10.710234303
RNF139CCNH0.707359303
RNF139RTN30.707216303

For details and further investigation, click here