| Full name: TNF receptor associated protein 1 | Alias Symbol: HSP75|HSP90L | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 10131 | HGNC ID: HGNC:16264 | Ensembl Gene: ENSG00000126602 | OMIM ID: 606219 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAP1 | 10131 | 201391_at | 0.6018 | 0.1833 | |
| GSE20347 | TRAP1 | 10131 | 201391_at | 0.2481 | 0.0549 | |
| GSE23400 | TRAP1 | 10131 | 201391_at | 0.1749 | 0.0048 | |
| GSE26886 | TRAP1 | 10131 | 201391_at | 0.4181 | 0.0062 | |
| GSE29001 | TRAP1 | 10131 | 201391_at | 0.3068 | 0.2602 | |
| GSE38129 | TRAP1 | 10131 | 201391_at | 0.3532 | 0.0249 | |
| GSE45670 | TRAP1 | 10131 | 201391_at | 0.2681 | 0.0883 | |
| GSE53622 | TRAP1 | 10131 | 9627 | 0.2682 | 0.0005 | |
| GSE53624 | TRAP1 | 10131 | 9627 | 0.3805 | 0.0000 | |
| GSE63941 | TRAP1 | 10131 | 201391_at | 1.9599 | 0.0001 | |
| GSE77861 | TRAP1 | 10131 | 201391_at | 0.1490 | 0.4823 | |
| GSE97050 | TRAP1 | 10131 | A_23_P3849 | 0.5283 | 0.2533 | |
| SRP007169 | TRAP1 | 10131 | RNAseq | 0.3438 | 0.3273 | |
| SRP008496 | TRAP1 | 10131 | RNAseq | 0.1153 | 0.6964 | |
| SRP064894 | TRAP1 | 10131 | RNAseq | -0.0609 | 0.7255 | |
| SRP133303 | TRAP1 | 10131 | RNAseq | 0.1764 | 0.4203 | |
| SRP159526 | TRAP1 | 10131 | RNAseq | 0.2106 | 0.4828 | |
| SRP193095 | TRAP1 | 10131 | RNAseq | 0.1136 | 0.3410 | |
| SRP219564 | TRAP1 | 10131 | RNAseq | 0.4711 | 0.3163 | |
| TCGA | TRAP1 | 10131 | RNAseq | 0.1410 | 0.0058 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAP1 | 10131 | 5 | 5 | 20 | |
| GSE20123 | TRAP1 | 10131 | 5 | 4 | 21 | |
| GSE43470 | TRAP1 | 10131 | 4 | 7 | 32 | |
| GSE46452 | TRAP1 | 10131 | 38 | 1 | 20 | |
| GSE47630 | TRAP1 | 10131 | 13 | 6 | 21 | |
| GSE54993 | TRAP1 | 10131 | 4 | 5 | 61 | |
| GSE54994 | TRAP1 | 10131 | 5 | 9 | 39 | |
| GSE60625 | TRAP1 | 10131 | 4 | 0 | 7 | |
| GSE74703 | TRAP1 | 10131 | 4 | 5 | 27 | |
| GSE74704 | TRAP1 | 10131 | 3 | 2 | 15 | |
| TCGA | TRAP1 | 10131 | 19 | 14 | 63 |
Total number of gains: 104; Total number of losses: 58; Total Number of normals: 326.
Somatic mutations of TRAP1:
Generating mutation plots.
Highly correlated genes for TRAP1:
Showing top 20/1174 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAP1 | FBXO16 | 0.803966 | 3 | 0 | 3 |
| TRAP1 | TRAPPC1 | 0.803752 | 3 | 0 | 3 |
| TRAP1 | ROMO1 | 0.787244 | 3 | 0 | 3 |
| TRAP1 | COMMD7 | 0.78234 | 3 | 0 | 3 |
| TRAP1 | IRF2BPL | 0.770387 | 3 | 0 | 3 |
| TRAP1 | ZNF267 | 0.768396 | 3 | 0 | 3 |
| TRAP1 | NSMCE4A | 0.762609 | 3 | 0 | 3 |
| TRAP1 | TMEM54 | 0.760546 | 3 | 0 | 3 |
| TRAP1 | GNB1 | 0.752845 | 3 | 0 | 3 |
| TRAP1 | RPS27A | 0.75266 | 3 | 0 | 3 |
| TRAP1 | TUFM | 0.75183 | 10 | 0 | 10 |
| TRAP1 | UBE2J2 | 0.750765 | 3 | 0 | 3 |
| TRAP1 | WDR89 | 0.749492 | 3 | 0 | 3 |
| TRAP1 | SRPK1 | 0.746544 | 4 | 0 | 4 |
| TRAP1 | USP28 | 0.741635 | 3 | 0 | 3 |
| TRAP1 | BTF3L4 | 0.740538 | 3 | 0 | 3 |
| TRAP1 | MRPL38 | 0.736213 | 6 | 0 | 6 |
| TRAP1 | IPO7 | 0.735223 | 3 | 0 | 3 |
| TRAP1 | DNAJA3 | 0.734972 | 12 | 0 | 11 |
| TRAP1 | IMMP1L | 0.731906 | 3 | 0 | 3 |
For details and further investigation, click here
