| Full name: ribonuclease P/MRP subunit p30 | Alias Symbol: TSG15 | ||
| Type: protein-coding gene | Cytoband: 10q23.31 | ||
| Entrez ID: 10556 | HGNC ID: HGNC:17688 | Ensembl Gene: ENSG00000148688 | OMIM ID: 606115 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPP30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPP30 | 10556 | 203436_at | 0.0480 | 0.9049 | |
| GSE20347 | RPP30 | 10556 | 203436_at | 0.2283 | 0.0990 | |
| GSE23400 | RPP30 | 10556 | 203436_at | 0.0270 | 0.5462 | |
| GSE26886 | RPP30 | 10556 | 203436_at | 0.0745 | 0.6225 | |
| GSE29001 | RPP30 | 10556 | 203436_at | 0.1152 | 0.6859 | |
| GSE38129 | RPP30 | 10556 | 203436_at | 0.3318 | 0.0014 | |
| GSE45670 | RPP30 | 10556 | 203436_at | 0.0970 | 0.6493 | |
| GSE53622 | RPP30 | 10556 | 112278 | -0.8376 | 0.0000 | |
| GSE53624 | RPP30 | 10556 | 112278 | -0.4674 | 0.0018 | |
| GSE63941 | RPP30 | 10556 | 203436_at | 0.2244 | 0.6626 | |
| GSE77861 | RPP30 | 10556 | 203436_at | -0.1656 | 0.5609 | |
| GSE97050 | RPP30 | 10556 | A_33_P3233666 | -0.1573 | 0.5143 | |
| SRP007169 | RPP30 | 10556 | RNAseq | -0.4896 | 0.3537 | |
| SRP008496 | RPP30 | 10556 | RNAseq | -0.0243 | 0.9481 | |
| SRP064894 | RPP30 | 10556 | RNAseq | 0.1754 | 0.2911 | |
| SRP133303 | RPP30 | 10556 | RNAseq | 0.1324 | 0.4329 | |
| SRP159526 | RPP30 | 10556 | RNAseq | -0.2506 | 0.4368 | |
| SRP193095 | RPP30 | 10556 | RNAseq | -0.2976 | 0.0021 | |
| SRP219564 | RPP30 | 10556 | RNAseq | -0.0974 | 0.7390 | |
| TCGA | RPP30 | 10556 | RNAseq | 0.0645 | 0.2707 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPP30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPP30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPP30 | 10556 | 1 | 7 | 22 | |
| GSE20123 | RPP30 | 10556 | 1 | 6 | 23 | |
| GSE43470 | RPP30 | 10556 | 0 | 8 | 35 | |
| GSE46452 | RPP30 | 10556 | 0 | 11 | 48 | |
| GSE47630 | RPP30 | 10556 | 2 | 14 | 24 | |
| GSE54993 | RPP30 | 10556 | 7 | 0 | 63 | |
| GSE54994 | RPP30 | 10556 | 1 | 11 | 41 | |
| GSE60625 | RPP30 | 10556 | 0 | 0 | 11 | |
| GSE74703 | RPP30 | 10556 | 0 | 6 | 30 | |
| GSE74704 | RPP30 | 10556 | 0 | 4 | 16 | |
| TCGA | RPP30 | 10556 | 7 | 27 | 62 |
Total number of gains: 19; Total number of losses: 94; Total Number of normals: 375.
Somatic mutations of RPP30:
Generating mutation plots.
Highly correlated genes for RPP30:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPP30 | PPM1A | 0.812982 | 3 | 0 | 3 |
| RPP30 | TRAPPC6B | 0.756097 | 3 | 0 | 3 |
| RPP30 | CSDE1 | 0.744246 | 3 | 0 | 3 |
| RPP30 | EAPP | 0.736348 | 3 | 0 | 3 |
| RPP30 | ARL16 | 0.733729 | 4 | 0 | 4 |
| RPP30 | COMMD2 | 0.731468 | 3 | 0 | 3 |
| RPP30 | FARS2 | 0.729243 | 3 | 0 | 3 |
| RPP30 | NDUFA13 | 0.727707 | 3 | 0 | 3 |
| RPP30 | LTN1 | 0.727161 | 3 | 0 | 3 |
| RPP30 | DIS3L | 0.726024 | 3 | 0 | 3 |
| RPP30 | TSEN34 | 0.722275 | 3 | 0 | 3 |
| RPP30 | PSMD1 | 0.720218 | 3 | 0 | 3 |
| RPP30 | ZNF354C | 0.715334 | 3 | 0 | 3 |
| RPP30 | KCTD10 | 0.715063 | 3 | 0 | 3 |
| RPP30 | AURKAIP1 | 0.714714 | 3 | 0 | 3 |
| RPP30 | GPRASP2 | 0.709751 | 3 | 0 | 3 |
| RPP30 | ATAD1 | 0.709058 | 5 | 0 | 5 |
| RPP30 | LMBR1 | 0.708605 | 3 | 0 | 3 |
| RPP30 | TADA2B | 0.708156 | 3 | 0 | 3 |
| RPP30 | PRKAG1 | 0.707032 | 3 | 0 | 3 |
For details and further investigation, click here
