OPN5

 

Full name: opsin 5 Alias Symbol: neuropsin|dJ402H5.1
Type: protein-coding gene Cytoband: 6p12.3
Entrez ID: 221391 HGNC ID: HGNC:19992 Ensembl Gene: ENSG00000124818 OMIM ID: 609042
Drug and gene relationship at DGIdb

 

Expression of OPN5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OPN5 221391 233657_at -0.2542 0.2753
GSE26886 OPN5 221391 233657_at 0.0127 0.9164
GSE45670 OPN5 221391 233657_at -0.0013 0.9905
GSE53622 OPN5 221391 39041 -0.5812 0.0000
GSE53624 OPN5 221391 39041 -0.2384 0.2521
GSE63941 OPN5 221391 233657_at 0.0851 0.5882
GSE77861 OPN5 221391 233657_at -0.3601 0.0065

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OPN5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of OPN5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OPN5 221391 5 2 23
GSE20123 OPN5 221391 5 2 23
GSE43470 OPN5 221391 5 1 37
GSE46452 OPN5 221391 2 10 47
GSE47630 OPN5 221391 7 5 28
GSE54993 OPN5 221391 3 1 66
GSE54994 OPN5 221391 7 3 43
GSE60625 OPN5 221391 0 3 8
GSE74703 OPN5 221391 5 1 30
GSE74704 OPN5 221391 1 1 18
TCGA OPN5 221391 19 14 63

Total number of gains: 59; Total number of losses: 43; Total Number of normals: 386.  


 

Somatic mutations of OPN5:

 

Generating mutation plots.

 

Highly correlated genes for OPN5:

 

Showing top 20/64 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OPN5RXFP30.690645303
OPN5HCRT0.684851303
OPN5OR11A10.665943303
OPN5WNT60.66348303
OPN5OR2J30.652522303
OPN5DCST10.64141303
OPN5PDLIM20.637645303
OPN5RAP1A0.637204303
OPN5OR7C10.631844303
OPN5LINC005570.629295303
OPN5TMEM1690.623872303
OPN5FSCN30.621124303
OPN5GP90.612683303
OPN5SMCP0.609312504
OPN5LMNTD10.606917403
OPN5GALR30.601805503
OPN5ZGLP10.601594403
OPN5SSTR40.597954303
OPN5OR2H10.596218404
OPN5CASC60.595353303

For details and further investigation, click here