| Full name: transmembrane protein 169 | Alias Symbol: FLJ34263 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 92691 | HGNC ID: HGNC:25130 | Ensembl Gene: ENSG00000163449 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM169:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM169 | 92691 | 228981_at | -0.0760 | 0.8356 | |
| GSE26886 | TMEM169 | 92691 | 228981_at | -0.0599 | 0.5204 | |
| GSE45670 | TMEM169 | 92691 | 228981_at | 0.0450 | 0.6651 | |
| GSE53622 | TMEM169 | 92691 | 166512 | 0.8103 | 0.0000 | |
| GSE53624 | TMEM169 | 92691 | 166512 | 0.6738 | 0.0002 | |
| GSE63941 | TMEM169 | 92691 | 228981_at | -0.0746 | 0.6559 | |
| GSE77861 | TMEM169 | 92691 | 228981_at | -0.1123 | 0.4220 | |
| SRP007169 | TMEM169 | 92691 | RNAseq | 2.0221 | 0.0350 | |
| SRP133303 | TMEM169 | 92691 | RNAseq | 0.4723 | 0.0237 | |
| SRP159526 | TMEM169 | 92691 | RNAseq | 0.5154 | 0.4176 | |
| SRP219564 | TMEM169 | 92691 | RNAseq | 0.8613 | 0.1244 | |
| TCGA | TMEM169 | 92691 | RNAseq | 0.6343 | 0.0423 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM169 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM169:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM169 | 92691 | 1 | 13 | 16 | |
| GSE20123 | TMEM169 | 92691 | 1 | 13 | 16 | |
| GSE43470 | TMEM169 | 92691 | 0 | 7 | 36 | |
| GSE46452 | TMEM169 | 92691 | 0 | 5 | 54 | |
| GSE47630 | TMEM169 | 92691 | 4 | 5 | 31 | |
| GSE54993 | TMEM169 | 92691 | 0 | 3 | 67 | |
| GSE54994 | TMEM169 | 92691 | 8 | 9 | 36 | |
| GSE60625 | TMEM169 | 92691 | 0 | 3 | 8 | |
| GSE74703 | TMEM169 | 92691 | 0 | 6 | 30 | |
| GSE74704 | TMEM169 | 92691 | 1 | 7 | 12 | |
| TCGA | TMEM169 | 92691 | 11 | 28 | 57 |
Total number of gains: 26; Total number of losses: 99; Total Number of normals: 363.
Somatic mutations of TMEM169:
Generating mutation plots.
Highly correlated genes for TMEM169:
Showing top 20/86 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM169 | PCGEM1 | 0.707947 | 3 | 0 | 3 |
| TMEM169 | PFKFB1 | 0.707163 | 3 | 0 | 3 |
| TMEM169 | AMBN | 0.70378 | 3 | 0 | 3 |
| TMEM169 | NYAP2 | 0.693119 | 3 | 0 | 3 |
| TMEM169 | OR1G1 | 0.677776 | 3 | 0 | 3 |
| TMEM169 | RGS3 | 0.670489 | 3 | 0 | 3 |
| TMEM169 | ANHX | 0.667905 | 3 | 0 | 3 |
| TMEM169 | DGKK | 0.661276 | 3 | 0 | 3 |
| TMEM169 | OR10H3 | 0.660562 | 3 | 0 | 3 |
| TMEM169 | CDH22 | 0.647837 | 3 | 0 | 3 |
| TMEM169 | EPHA5-AS1 | 0.641476 | 3 | 0 | 3 |
| TMEM169 | CELA3A | 0.63496 | 3 | 0 | 3 |
| TMEM169 | VKORC1 | 0.630151 | 3 | 0 | 3 |
| TMEM169 | SLC5A2 | 0.629829 | 3 | 0 | 3 |
| TMEM169 | PRAMEF11 | 0.627132 | 3 | 0 | 3 |
| TMEM169 | MSX2 | 0.624767 | 4 | 0 | 4 |
| TMEM169 | OPN5 | 0.623872 | 3 | 0 | 3 |
| TMEM169 | LINC00574 | 0.619571 | 3 | 0 | 3 |
| TMEM169 | C4orf45 | 0.618497 | 3 | 0 | 3 |
| TMEM169 | IFNL1 | 0.618027 | 3 | 0 | 3 |
For details and further investigation, click here
