| Full name: glycoprotein IX platelet | Alias Symbol: CD42a|GPIX | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 2815 | HGNC ID: HGNC:4444 | Ensembl Gene: ENSG00000169704 | OMIM ID: 173515 |
| Drug and gene relationship at DGIdb | |||
GP9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04611 | Platelet activation |
Expression of GP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GP9 | 2815 | 206883_x_at | -0.1236 | 0.5908 | |
| GSE20347 | GP9 | 2815 | 206883_x_at | -0.0053 | 0.9697 | |
| GSE23400 | GP9 | 2815 | 206883_x_at | -0.2585 | 0.0000 | |
| GSE26886 | GP9 | 2815 | 206883_x_at | 0.1979 | 0.0560 | |
| GSE29001 | GP9 | 2815 | 206883_x_at | -0.1121 | 0.5310 | |
| GSE38129 | GP9 | 2815 | 206883_x_at | -0.1232 | 0.0755 | |
| GSE45670 | GP9 | 2815 | 206883_x_at | 0.0327 | 0.7349 | |
| GSE53622 | GP9 | 2815 | 31616 | 0.3122 | 0.0258 | |
| GSE53624 | GP9 | 2815 | 31616 | 0.0247 | 0.8935 | |
| GSE63941 | GP9 | 2815 | 206883_x_at | 0.1316 | 0.4424 | |
| GSE77861 | GP9 | 2815 | 206883_x_at | -0.1715 | 0.0986 | |
| GSE97050 | GP9 | 2815 | A_33_P3383226 | -0.0064 | 0.9811 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GP9 | 2815 | 17 | 0 | 13 | |
| GSE20123 | GP9 | 2815 | 17 | 0 | 13 | |
| GSE43470 | GP9 | 2815 | 19 | 0 | 24 | |
| GSE46452 | GP9 | 2815 | 14 | 5 | 40 | |
| GSE47630 | GP9 | 2815 | 18 | 3 | 19 | |
| GSE54993 | GP9 | 2815 | 2 | 7 | 61 | |
| GSE54994 | GP9 | 2815 | 31 | 3 | 19 | |
| GSE60625 | GP9 | 2815 | 0 | 6 | 5 | |
| GSE74703 | GP9 | 2815 | 17 | 0 | 19 | |
| GSE74704 | GP9 | 2815 | 13 | 0 | 7 | |
| TCGA | GP9 | 2815 | 58 | 5 | 33 |
Total number of gains: 206; Total number of losses: 29; Total Number of normals: 253.
Somatic mutations of GP9:
Generating mutation plots.
Highly correlated genes for GP9:
Showing top 20/1311 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GP9 | ZGLP1 | 0.869267 | 3 | 0 | 3 |
| GP9 | PPP1R3F | 0.784302 | 3 | 0 | 3 |
| GP9 | MAMLD1 | 0.782375 | 3 | 0 | 3 |
| GP9 | TSSK3 | 0.765673 | 3 | 0 | 3 |
| GP9 | TTC39A | 0.763309 | 3 | 0 | 3 |
| GP9 | PTPRN2 | 0.75826 | 5 | 0 | 5 |
| GP9 | IQCF3 | 0.756906 | 3 | 0 | 3 |
| GP9 | PNPLA7 | 0.753793 | 3 | 0 | 3 |
| GP9 | GRID1 | 0.725843 | 4 | 0 | 3 |
| GP9 | FAM78B | 0.724788 | 3 | 0 | 3 |
| GP9 | C4orf45 | 0.721849 | 3 | 0 | 3 |
| GP9 | SPTBN5 | 0.720758 | 3 | 0 | 3 |
| GP9 | CRB2 | 0.71941 | 4 | 0 | 3 |
| GP9 | KRT20 | 0.713131 | 3 | 0 | 3 |
| GP9 | LMAN1L | 0.708685 | 7 | 0 | 6 |
| GP9 | PM20D1 | 0.706104 | 3 | 0 | 3 |
| GP9 | CHRD | 0.699835 | 7 | 0 | 6 |
| GP9 | C17orf64 | 0.698358 | 3 | 0 | 3 |
| GP9 | SHANK1 | 0.696409 | 6 | 0 | 5 |
| GP9 | KCNK9 | 0.695663 | 4 | 0 | 3 |
For details and further investigation, click here
