| Full name: oxidative stress induced growth inhibitor family member 2 | Alias Symbol: hT41 | ||
| Type: protein-coding gene | Cytoband: 8q21.3 | ||
| Entrez ID: 734 | HGNC ID: HGNC:1355 | Ensembl Gene: ENSG00000164823 | OMIM ID: 604598 |
| Drug and gene relationship at DGIdb | |||
Expression of OSGIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSGIN2 | 734 | 1554414_a_at | 0.6749 | 0.3334 | |
| GSE20347 | OSGIN2 | 734 | 41553_at | -0.0342 | 0.5275 | |
| GSE23400 | OSGIN2 | 734 | 204024_at | 0.0948 | 0.0153 | |
| GSE26886 | OSGIN2 | 734 | 1554414_a_at | 1.2025 | 0.0000 | |
| GSE29001 | OSGIN2 | 734 | 41553_at | -0.1212 | 0.4828 | |
| GSE38129 | OSGIN2 | 734 | 41553_at | -0.1570 | 0.0456 | |
| GSE45670 | OSGIN2 | 734 | 1554414_a_at | 0.5300 | 0.0200 | |
| GSE53622 | OSGIN2 | 734 | 156238 | 0.3188 | 0.0002 | |
| GSE53624 | OSGIN2 | 734 | 156238 | 0.5179 | 0.0000 | |
| GSE63941 | OSGIN2 | 734 | 1554414_a_at | -0.3835 | 0.5114 | |
| GSE77861 | OSGIN2 | 734 | 1554414_a_at | 0.5636 | 0.0586 | |
| GSE97050 | OSGIN2 | 734 | A_23_P82859 | -0.2621 | 0.5869 | |
| SRP007169 | OSGIN2 | 734 | RNAseq | 1.4673 | 0.0007 | |
| SRP008496 | OSGIN2 | 734 | RNAseq | 1.6452 | 0.0000 | |
| SRP064894 | OSGIN2 | 734 | RNAseq | 0.9214 | 0.0000 | |
| SRP133303 | OSGIN2 | 734 | RNAseq | 0.7037 | 0.0000 | |
| SRP159526 | OSGIN2 | 734 | RNAseq | 1.0494 | 0.0020 | |
| SRP193095 | OSGIN2 | 734 | RNAseq | 0.7945 | 0.0000 | |
| SRP219564 | OSGIN2 | 734 | RNAseq | 0.4753 | 0.3728 | |
| TCGA | OSGIN2 | 734 | RNAseq | 0.0503 | 0.4576 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by OSGIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSGIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSGIN2 | 734 | 14 | 1 | 15 | |
| GSE20123 | OSGIN2 | 734 | 15 | 1 | 14 | |
| GSE43470 | OSGIN2 | 734 | 20 | 1 | 22 | |
| GSE46452 | OSGIN2 | 734 | 22 | 0 | 37 | |
| GSE47630 | OSGIN2 | 734 | 23 | 0 | 17 | |
| GSE54993 | OSGIN2 | 734 | 0 | 20 | 50 | |
| GSE54994 | OSGIN2 | 734 | 33 | 1 | 19 | |
| GSE60625 | OSGIN2 | 734 | 0 | 4 | 7 | |
| GSE74703 | OSGIN2 | 734 | 17 | 1 | 18 | |
| GSE74704 | OSGIN2 | 734 | 10 | 0 | 10 | |
| TCGA | OSGIN2 | 734 | 55 | 1 | 40 |
Total number of gains: 209; Total number of losses: 30; Total Number of normals: 249.
Somatic mutations of OSGIN2:
Generating mutation plots.
Highly correlated genes for OSGIN2:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSGIN2 | DCAF13 | 0.714053 | 3 | 0 | 3 |
| OSGIN2 | ZNF511 | 0.70411 | 4 | 0 | 4 |
| OSGIN2 | RUNX3 | 0.695049 | 3 | 0 | 3 |
| OSGIN2 | FGF16 | 0.685191 | 3 | 0 | 3 |
| OSGIN2 | KXD1 | 0.680321 | 4 | 0 | 3 |
| OSGIN2 | STK3 | 0.678825 | 5 | 0 | 4 |
| OSGIN2 | HNRNPLL | 0.678107 | 6 | 0 | 6 |
| OSGIN2 | RAB3IP | 0.676893 | 3 | 0 | 3 |
| OSGIN2 | SLC52A2 | 0.672622 | 3 | 0 | 3 |
| OSGIN2 | POU6F2-AS2 | 0.670241 | 3 | 0 | 3 |
| OSGIN2 | LRRC49 | 0.66922 | 5 | 0 | 4 |
| OSGIN2 | KIR2DL5A | 0.668382 | 3 | 0 | 3 |
| OSGIN2 | COPRS | 0.668025 | 6 | 0 | 6 |
| OSGIN2 | COL28A1 | 0.665522 | 3 | 0 | 3 |
| OSGIN2 | CDCA7L | 0.663355 | 7 | 0 | 7 |
| OSGIN2 | PITX2 | 0.663171 | 4 | 0 | 3 |
| OSGIN2 | TNFRSF10C | 0.660365 | 3 | 0 | 3 |
| OSGIN2 | KNSTRN | 0.65844 | 4 | 0 | 4 |
| OSGIN2 | MED30 | 0.654318 | 7 | 0 | 5 |
| OSGIN2 | METTL23 | 0.650815 | 5 | 0 | 4 |
For details and further investigation, click here
