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File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
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Multi-Omics Database of ESCC

 

SLC52A2

 

Full name: solute carrier family 52 member 2 Alias Symbol: FLJ11856|PAR1|GPCR41|D15Ertd747e|RFVT2|hRFT3
Type: protein-coding gene Cytoband: 8q24.3
Entrez ID: 79581 HGNC ID: HGNC:30224 Ensembl Gene: ENSG00000185803 OMIM ID: 607882
Drug and gene relationship at DGIdb

 

Expression of SLC52A2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC52A2 79581 218151_x_at 1.1196 0.0359
GSE20347 SLC52A2 79581 218151_x_at 0.5989 0.0000
GSE23400 SLC52A2 79581 218151_x_at 0.4189 0.0000
GSE26886 SLC52A2 79581 218151_x_at 0.6511 0.0001
GSE29001 SLC52A2 79581 218151_x_at 0.7173 0.0186
GSE38129 SLC52A2 79581 218151_x_at 0.7564 0.0000
GSE45670 SLC52A2 79581 218151_x_at 0.7323 0.0000
GSE53622 SLC52A2 79581 9756 0.2623 0.0003
GSE53624 SLC52A2 79581 9756 0.7112 0.0000
GSE63941 SLC52A2 79581 218151_x_at -0.2541 0.6205
GSE77861 SLC52A2 79581 218151_x_at 0.3449 0.1079
SRP007169 SLC52A2 79581 RNAseq 0.3579 0.3509
SRP008496 SLC52A2 79581 RNAseq 0.4833 0.0891
SRP064894 SLC52A2 79581 RNAseq 1.8374 0.0000
SRP133303 SLC52A2 79581 RNAseq 1.2750 0.0000
SRP159526 SLC52A2 79581 RNAseq 0.6768 0.0482
SRP193095 SLC52A2 79581 RNAseq 0.9190 0.0000
SRP219564 SLC52A2 79581 RNAseq 1.4750 0.0074

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by SLC52A2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of SLC52A2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC52A2 79581 17 1 12
GSE20123 SLC52A2 79581 17 1 12
GSE43470 SLC52A2 79581 16 2 25
GSE46452 SLC52A2 79581 28 0 31
GSE47630 SLC52A2 79581 25 1 14
GSE54993 SLC52A2 79581 0 25 45
GSE54994 SLC52A2 79581 39 1 13
GSE60625 SLC52A2 79581 3 4 4
GSE74703 SLC52A2 79581 14 1 21
GSE74704 SLC52A2 79581 10 0 10
TCGA SLC52A2 79581 63 2 31

Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.  

 

Somatic mutations of SLC52A2:

 

Generating mutation plots.

 

Highly correlated genes for SLC52A2:

 

Showing top 20/1411 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC52A2C8orf760.790778303
SLC52A2GNPNAT10.788305303
SLC52A2SLC39A40.78590210010
SLC52A2KRTCAP20.777841404
SLC52A2KPNA20.753767504
SLC52A2MTERF30.748815706
SLC52A2ZDHHC80.746383303
SLC52A2PUF600.72389811011
SLC52A2MRPL470.723625404
SLC52A2NEU10.721777404
SLC52A2TOP1MT0.718792706
SLC52A2HSF10.71769411010
SLC52A2LRRC580.714131303
SLC52A2MRPL360.712572303
SLC52A2EXOSC40.70954211011
SLC52A2UBQLN40.709406404
SLC52A2SURF60.709293403
SLC52A2DERL10.70662807
SLC52A2TCOF10.702894908
SLC52A2YDJC0.702594606

For details and further investigation, click here