| Full name: leucine rich repeat containing 49 | Alias Symbol: FLJ20156 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 54839 | HGNC ID: HGNC:25965 | Ensembl Gene: ENSG00000137821 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC49 | 54839 | 219338_s_at | -0.5158 | 0.4106 | |
| GSE20347 | LRRC49 | 54839 | 219338_s_at | 0.5611 | 0.0052 | |
| GSE23400 | LRRC49 | 54839 | 219338_s_at | -0.0374 | 0.4247 | |
| GSE26886 | LRRC49 | 54839 | 219338_s_at | 1.8232 | 0.0000 | |
| GSE29001 | LRRC49 | 54839 | 219338_s_at | 0.1617 | 0.5364 | |
| GSE38129 | LRRC49 | 54839 | 219338_s_at | 0.2322 | 0.2524 | |
| GSE45670 | LRRC49 | 54839 | 219338_s_at | -0.5428 | 0.0199 | |
| GSE53622 | LRRC49 | 54839 | 9295 | 0.1314 | 0.2937 | |
| GSE53624 | LRRC49 | 54839 | 9295 | 0.2407 | 0.0138 | |
| GSE63941 | LRRC49 | 54839 | 219338_s_at | -0.5955 | 0.3489 | |
| GSE77861 | LRRC49 | 54839 | 219338_s_at | 0.1922 | 0.1445 | |
| GSE97050 | LRRC49 | 54839 | A_33_P3344399 | -0.2934 | 0.3130 | |
| SRP007169 | LRRC49 | 54839 | RNAseq | 1.7127 | 0.0114 | |
| SRP008496 | LRRC49 | 54839 | RNAseq | 1.6181 | 0.0004 | |
| SRP064894 | LRRC49 | 54839 | RNAseq | 0.0709 | 0.7532 | |
| SRP133303 | LRRC49 | 54839 | RNAseq | 0.2530 | 0.1544 | |
| SRP159526 | LRRC49 | 54839 | RNAseq | 0.2537 | 0.4619 | |
| SRP193095 | LRRC49 | 54839 | RNAseq | 0.5933 | 0.0000 | |
| SRP219564 | LRRC49 | 54839 | RNAseq | -0.2762 | 0.6172 | |
| TCGA | LRRC49 | 54839 | RNAseq | -0.2855 | 0.0258 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LRRC49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC49 | 54839 | 7 | 1 | 22 | |
| GSE20123 | LRRC49 | 54839 | 7 | 1 | 22 | |
| GSE43470 | LRRC49 | 54839 | 4 | 6 | 33 | |
| GSE46452 | LRRC49 | 54839 | 3 | 7 | 49 | |
| GSE47630 | LRRC49 | 54839 | 8 | 10 | 22 | |
| GSE54993 | LRRC49 | 54839 | 5 | 6 | 59 | |
| GSE54994 | LRRC49 | 54839 | 6 | 8 | 39 | |
| GSE60625 | LRRC49 | 54839 | 4 | 4 | 3 | |
| GSE74703 | LRRC49 | 54839 | 4 | 3 | 29 | |
| GSE74704 | LRRC49 | 54839 | 3 | 1 | 16 | |
| TCGA | LRRC49 | 54839 | 10 | 15 | 71 |
Total number of gains: 61; Total number of losses: 62; Total Number of normals: 365.
Somatic mutations of LRRC49:
Generating mutation plots.
Highly correlated genes for LRRC49:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC49 | TPPP3 | 0.759071 | 3 | 0 | 3 |
| LRRC49 | ITSN1 | 0.740355 | 3 | 0 | 3 |
| LRRC49 | ANO5 | 0.707797 | 3 | 0 | 3 |
| LRRC49 | TNPO2 | 0.69174 | 3 | 0 | 3 |
| LRRC49 | GYG1 | 0.682659 | 4 | 0 | 3 |
| LRRC49 | OSGIN2 | 0.66922 | 5 | 0 | 4 |
| LRRC49 | NEGR1 | 0.662432 | 3 | 0 | 3 |
| LRRC49 | DTX3 | 0.659582 | 5 | 0 | 5 |
| LRRC49 | HEXA | 0.659547 | 4 | 0 | 4 |
| LRRC49 | NCOR2 | 0.656641 | 4 | 0 | 4 |
| LRRC49 | TCEAL3 | 0.656361 | 4 | 0 | 4 |
| LRRC49 | SH3BGR | 0.640751 | 5 | 0 | 4 |
| LRRC49 | CHST10 | 0.640447 | 4 | 0 | 4 |
| LRRC49 | PRKCA | 0.638832 | 6 | 0 | 5 |
| LRRC49 | LOH12CR2 | 0.633949 | 4 | 0 | 3 |
| LRRC49 | CDK6 | 0.63311 | 3 | 0 | 3 |
| LRRC49 | KITLG | 0.632329 | 5 | 0 | 4 |
| LRRC49 | CENPV | 0.631866 | 5 | 0 | 3 |
| LRRC49 | ZNF385D | 0.628322 | 4 | 0 | 3 |
| LRRC49 | RAI14 | 0.627868 | 7 | 0 | 6 |
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