CDCA7L

 

Full name: cell division cycle associated 7 like Alias Symbol: RAM2|R1|JPO2
Type: protein-coding gene Cytoband: 7p15.3
Entrez ID: 55536 HGNC ID: HGNC:30777 Ensembl Gene: ENSG00000164649 OMIM ID: 609685
Drug and gene relationship at DGIdb

 

Expression of CDCA7L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDCA7L 55536 225081_s_at 0.9953 0.0965
GSE26886 CDCA7L 55536 225081_s_at 2.8206 0.0000
GSE45670 CDCA7L 55536 225081_s_at 0.3562 0.2622
GSE53622 CDCA7L 55536 101377 1.2971 0.0000
GSE53624 CDCA7L 55536 101377 1.3916 0.0000
GSE63941 CDCA7L 55536 225081_s_at 2.0307 0.0005
GSE77861 CDCA7L 55536 225081_s_at 1.1700 0.0143
GSE97050 CDCA7L 55536 A_24_P274795 0.0624 0.8709
SRP007169 CDCA7L 55536 RNAseq 2.2548 0.0000
SRP008496 CDCA7L 55536 RNAseq 2.0962 0.0000
SRP064894 CDCA7L 55536 RNAseq 0.9084 0.0001
SRP133303 CDCA7L 55536 RNAseq 1.0939 0.0000
SRP159526 CDCA7L 55536 RNAseq 1.0079 0.0001
SRP193095 CDCA7L 55536 RNAseq 0.9888 0.0000
SRP219564 CDCA7L 55536 RNAseq 0.5016 0.2816
TCGA CDCA7L 55536 RNAseq 0.1707 0.0361

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by CDCA7L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CDCA7L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDCA7L 55536 17 1 12
GSE20123 CDCA7L 55536 17 1 12
GSE43470 CDCA7L 55536 4 0 39
GSE46452 CDCA7L 55536 10 2 47
GSE47630 CDCA7L 55536 9 1 30
GSE54993 CDCA7L 55536 0 6 64
GSE54994 CDCA7L 55536 20 2 31
GSE60625 CDCA7L 55536 0 0 11
GSE74703 CDCA7L 55536 4 0 32
GSE74704 CDCA7L 55536 11 1 8
TCGA CDCA7L 55536 57 4 35

Total number of gains: 149; Total number of losses: 18; Total Number of normals: 321.  

 

Somatic mutations of CDCA7L:

 

Generating mutation plots.

 

Highly correlated genes for CDCA7L:

 

Showing top 20/887 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDCA7LLPCAT10.760894606
CDCA7LWDR540.750421606
CDCA7LIRF60.738076303
CDCA7LMTERF30.733195404
CDCA7LBRAT10.724246707
CDCA7LCBX30.719462807
CDCA7LTHOC50.718033606
CDCA7LSLC25A320.716547606
CDCA7LEIF5A20.715767606
CDCA7LGNA120.714032606
CDCA7LCOL4A20.712065606
CDCA7LCMSS10.710803707
CDCA7LCABYR0.710793606
CDCA7LMFAP20.706605606
CDCA7LTMEM184B0.704273606
CDCA7LPOLA20.700692606
CDCA7LPLOD30.700563606
CDCA7LACD0.698621707
CDCA7LTCF30.697322606
CDCA7LSERPINH10.696665706

For details and further investigation, click here