| Full name: collagen type XXVIII alpha 1 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p21.3 | ||
| Entrez ID: 340267 | HGNC ID: HGNC:22442 | Ensembl Gene: ENSG00000215018 | OMIM ID: 609996 |
| Drug and gene relationship at DGIdb | |||
Expression of COL28A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL28A1 | 340267 | 239921_at | -1.0177 | 0.2535 | |
| GSE26886 | COL28A1 | 340267 | 242345_at | 1.3531 | 0.0005 | |
| GSE45670 | COL28A1 | 340267 | 242345_at | 0.4865 | 0.2268 | |
| GSE53622 | COL28A1 | 340267 | 45806 | -1.0555 | 0.0000 | |
| GSE53624 | COL28A1 | 340267 | 45806 | -0.7439 | 0.0000 | |
| GSE63941 | COL28A1 | 340267 | 242345_at | 1.0143 | 0.0615 | |
| GSE77861 | COL28A1 | 340267 | 242345_at | 0.3154 | 0.1687 | |
| GSE97050 | COL28A1 | 340267 | A_33_P3243787 | -1.0084 | 0.2468 | |
| SRP064894 | COL28A1 | 340267 | RNAseq | 0.5929 | 0.1548 | |
| SRP133303 | COL28A1 | 340267 | RNAseq | -0.4899 | 0.1967 | |
| SRP159526 | COL28A1 | 340267 | RNAseq | 0.3572 | 0.1130 | |
| SRP193095 | COL28A1 | 340267 | RNAseq | -0.0213 | 0.9481 | |
| SRP219564 | COL28A1 | 340267 | RNAseq | 0.2827 | 0.6938 | |
| TCGA | COL28A1 | 340267 | RNAseq | -0.6461 | 0.0633 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by COL28A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL28A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL28A1 | 340267 | 15 | 2 | 13 | |
| GSE20123 | COL28A1 | 340267 | 15 | 2 | 13 | |
| GSE43470 | COL28A1 | 340267 | 8 | 0 | 35 | |
| GSE46452 | COL28A1 | 340267 | 11 | 1 | 47 | |
| GSE47630 | COL28A1 | 340267 | 9 | 1 | 30 | |
| GSE54993 | COL28A1 | 340267 | 0 | 6 | 64 | |
| GSE54994 | COL28A1 | 340267 | 21 | 1 | 31 | |
| GSE60625 | COL28A1 | 340267 | 0 | 0 | 11 | |
| GSE74703 | COL28A1 | 340267 | 8 | 0 | 28 | |
| GSE74704 | COL28A1 | 340267 | 9 | 1 | 10 | |
| TCGA | COL28A1 | 340267 | 56 | 4 | 36 |
Total number of gains: 152; Total number of losses: 18; Total Number of normals: 318.
Somatic mutations of COL28A1:
Generating mutation plots.
Highly correlated genes for COL28A1:
Showing top 20/263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL28A1 | XKR4 | 0.764363 | 3 | 0 | 3 |
| COL28A1 | NEK9 | 0.759636 | 3 | 0 | 3 |
| COL28A1 | BCHE | 0.755034 | 3 | 0 | 3 |
| COL28A1 | PRKG2 | 0.749533 | 3 | 0 | 3 |
| COL28A1 | NCAM1 | 0.733292 | 4 | 0 | 4 |
| COL28A1 | CACNB2 | 0.7299 | 3 | 0 | 3 |
| COL28A1 | HSPB7 | 0.722525 | 3 | 0 | 3 |
| COL28A1 | UBXN10 | 0.721308 | 4 | 0 | 3 |
| COL28A1 | ILDR2 | 0.719892 | 3 | 0 | 3 |
| COL28A1 | PCSK2 | 0.719624 | 3 | 0 | 3 |
| COL28A1 | RBM38 | 0.716537 | 3 | 0 | 3 |
| COL28A1 | C1QTNF7 | 0.715067 | 3 | 0 | 3 |
| COL28A1 | TACR2 | 0.711298 | 3 | 0 | 3 |
| COL28A1 | SGCA | 0.709148 | 3 | 0 | 3 |
| COL28A1 | CGRRF1 | 0.707607 | 3 | 0 | 3 |
| COL28A1 | BAG2 | 0.705777 | 3 | 0 | 3 |
| COL28A1 | MYOM1 | 0.703205 | 3 | 0 | 3 |
| COL28A1 | PAM | 0.702155 | 3 | 0 | 3 |
| COL28A1 | PGR | 0.701791 | 4 | 0 | 3 |
| COL28A1 | MYOT | 0.701158 | 3 | 0 | 3 |
For details and further investigation, click here
