| Full name: mediator complex subunit 30 | Alias Symbol: TRAP25 | ||
| Type: protein-coding gene | Cytoband: 8q24.11 | ||
| Entrez ID: 90390 | HGNC ID: HGNC:23032 | Ensembl Gene: ENSG00000164758 | OMIM ID: 610237 |
| Drug and gene relationship at DGIdb | |||
Expression of MED30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED30 | 90390 | 227787_s_at | 0.7875 | 0.0225 | |
| GSE26886 | MED30 | 90390 | 227786_at | 1.7473 | 0.0000 | |
| GSE45670 | MED30 | 90390 | 227787_s_at | 0.5421 | 0.0778 | |
| GSE53622 | MED30 | 90390 | 12730 | 0.7608 | 0.0000 | |
| GSE53624 | MED30 | 90390 | 12730 | 1.0843 | 0.0000 | |
| GSE63941 | MED30 | 90390 | 227787_s_at | 2.2038 | 0.0009 | |
| GSE77861 | MED30 | 90390 | 227787_s_at | 1.0832 | 0.0105 | |
| GSE97050 | MED30 | 90390 | A_23_P31866 | 0.1826 | 0.4850 | |
| SRP007169 | MED30 | 90390 | RNAseq | 0.4577 | 0.2331 | |
| SRP008496 | MED30 | 90390 | RNAseq | 0.7670 | 0.0081 | |
| SRP064894 | MED30 | 90390 | RNAseq | 0.9630 | 0.0001 | |
| SRP133303 | MED30 | 90390 | RNAseq | 0.6021 | 0.0000 | |
| SRP159526 | MED30 | 90390 | RNAseq | 0.8053 | 0.0005 | |
| SRP193095 | MED30 | 90390 | RNAseq | 0.6880 | 0.0000 | |
| SRP219564 | MED30 | 90390 | RNAseq | 0.4987 | 0.0853 | |
| TCGA | MED30 | 90390 | RNAseq | 0.4996 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by MED30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED30 | 90390 | 18 | 1 | 11 | |
| GSE20123 | MED30 | 90390 | 19 | 1 | 10 | |
| GSE43470 | MED30 | 90390 | 22 | 0 | 21 | |
| GSE46452 | MED30 | 90390 | 26 | 0 | 33 | |
| GSE47630 | MED30 | 90390 | 24 | 0 | 16 | |
| GSE54993 | MED30 | 90390 | 0 | 20 | 50 | |
| GSE54994 | MED30 | 90390 | 37 | 1 | 15 | |
| GSE60625 | MED30 | 90390 | 0 | 4 | 7 | |
| GSE74703 | MED30 | 90390 | 19 | 0 | 17 | |
| GSE74704 | MED30 | 90390 | 12 | 1 | 7 | |
| TCGA | MED30 | 90390 | 66 | 2 | 28 |
Total number of gains: 243; Total number of losses: 30; Total Number of normals: 215.
Somatic mutations of MED30:
Generating mutation plots.
Highly correlated genes for MED30:
Showing top 20/1847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED30 | CCDC127 | 0.793782 | 3 | 0 | 3 |
| MED30 | KLF13 | 0.789965 | 4 | 0 | 4 |
| MED30 | SLC25A32 | 0.778383 | 7 | 0 | 7 |
| MED30 | RPL19 | 0.772568 | 3 | 0 | 3 |
| MED30 | ZNF707 | 0.766582 | 3 | 0 | 3 |
| MED30 | INPP5B | 0.763947 | 3 | 0 | 3 |
| MED30 | ABHD3 | 0.760303 | 3 | 0 | 3 |
| MED30 | U2SURP | 0.758537 | 6 | 0 | 6 |
| MED30 | RAD21 | 0.754668 | 7 | 0 | 6 |
| MED30 | INO80B | 0.74806 | 3 | 0 | 3 |
| MED30 | PUF60 | 0.747751 | 8 | 0 | 7 |
| MED30 | KCNE3 | 0.747465 | 3 | 0 | 3 |
| MED30 | DMTF1 | 0.74727 | 3 | 0 | 3 |
| MED30 | LRP5L | 0.746975 | 3 | 0 | 3 |
| MED30 | HLTF | 0.746904 | 8 | 0 | 8 |
| MED30 | UBE2T | 0.745735 | 9 | 0 | 9 |
| MED30 | STK3 | 0.742615 | 7 | 0 | 7 |
| MED30 | TSC22D1 | 0.739194 | 3 | 0 | 3 |
| MED30 | MMS22L | 0.738213 | 3 | 0 | 3 |
| MED30 | A4GALT | 0.73695 | 3 | 0 | 3 |
For details and further investigation, click here
