OTX2-AS1

 

Full name: OTX2 antisense RNA 1 (head to head) Alias Symbol: OTX2OS1
Type: non-coding RNA Cytoband: 14q22.3
Entrez ID: 100309464 HGNC ID: HGNC:43906 Ensembl Gene: ENSG00000248550 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of OTX2-AS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OTX2-AS1 100309464 1561319_at 0.2406 0.3937
GSE26886 OTX2-AS1 100309464 1561319_at -0.0368 0.6873
GSE45670 OTX2-AS1 100309464 1561319_at 0.2760 0.0055
GSE53622 OTX2-AS1 100309464 107707 0.2169 0.0068
GSE53624 OTX2-AS1 100309464 107707 0.0894 0.3305
GSE63941 OTX2-AS1 100309464 1561319_at 0.0984 0.4171
GSE77861 OTX2-AS1 100309464 1561319_at -0.0059 0.9549
SRP133303 OTX2-AS1 100309464 RNAseq 0.0051 0.9743
SRP193095 OTX2-AS1 100309464 RNAseq 0.4249 0.0208
SRP219564 OTX2-AS1 100309464 RNAseq 0.8608 0.0938

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OTX2-AS1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of OTX2-AS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OTX2-AS1 100309464 8 3 19
GSE20123 OTX2-AS1 100309464 8 3 19
GSE43470 OTX2-AS1 100309464 9 2 32
GSE46452 OTX2-AS1 100309464 16 3 40
GSE47630 OTX2-AS1 100309464 11 10 19
GSE54993 OTX2-AS1 100309464 3 8 59
GSE54994 OTX2-AS1 100309464 19 4 30
GSE60625 OTX2-AS1 100309464 0 2 9
GSE74703 OTX2-AS1 100309464 8 2 26
GSE74704 OTX2-AS1 100309464 3 2 15

Total number of gains: 85; Total number of losses: 39; Total Number of normals: 268.  


 

Somatic mutations of OTX2-AS1:

 

Generating mutation plots.

 

Highly correlated genes for OTX2-AS1:

 

Showing all 14 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OTX2-AS1RAB3B0.706384303
OTX2-AS1CACNA2D30.609776303
OTX2-AS1PDE6C0.598952403
OTX2-AS1SLC4A20.59689303
OTX2-AS1GPR1820.589003303
OTX2-AS1SLC1A70.579459403
OTX2-AS1CBR10.575265303
OTX2-AS1DPH50.566635303
OTX2-AS1SNHG40.562366303
OTX2-AS1GSTM40.556033303
OTX2-AS1FAM71F10.549707303
OTX2-AS1TSSK30.528643503
OTX2-AS1SHISA70.507103403
OTX2-AS1PRODH20.50679603

For details and further investigation, click here