RAB3B

 

Full name: RAB3B, member RAS oncogene family Alias Symbol: 
Type: protein-coding gene Cytoband: 1p32.3
Entrez ID: 5865 HGNC ID: HGNC:9778 Ensembl Gene: ENSG00000169213 OMIM ID: 179510
Drug and gene relationship at DGIdb

 

Expression of RAB3B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAB3B 5865 239202_at 0.2931 0.2841
GSE20347 RAB3B 5865 205924_at 0.2617 0.0193
GSE23400 RAB3B 5865 205924_at 0.0374 0.5345
GSE26886 RAB3B 5865 205924_at 0.6359 0.0736
GSE29001 RAB3B 5865 205924_at -0.0251 0.8593
GSE38129 RAB3B 5865 205924_at 0.6469 0.0001
GSE45670 RAB3B 5865 239202_at 0.5940 0.1858
GSE53622 RAB3B 5865 35752 3.7529 0.0000
GSE53624 RAB3B 5865 35752 3.7873 0.0000
GSE63941 RAB3B 5865 239202_at -2.5178 0.0108
GSE77861 RAB3B 5865 205924_at 0.1006 0.5654
SRP007169 RAB3B 5865 RNAseq 5.9703 0.0000
SRP008496 RAB3B 5865 RNAseq 5.4195 0.0000
SRP064894 RAB3B 5865 RNAseq 1.7734 0.0000
SRP133303 RAB3B 5865 RNAseq 1.1395 0.0001
SRP159526 RAB3B 5865 RNAseq 4.3378 0.0000
SRP193095 RAB3B 5865 RNAseq 1.5141 0.0000
SRP219564 RAB3B 5865 RNAseq 1.1984 0.0029
TCGA RAB3B 5865 RNAseq 0.3686 0.4234

Upregulated datasets: 9; Downregulated datasets: 1.  

 

Survival by RAB3B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RAB3B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAB3B 5865 3 4 23
GSE20123 RAB3B 5865 3 3 24
GSE43470 RAB3B 5865 5 4 34
GSE46452 RAB3B 5865 2 1 56
GSE47630 RAB3B 5865 8 4 28
GSE54993 RAB3B 5865 0 1 69
GSE54994 RAB3B 5865 11 2 40
GSE60625 RAB3B 5865 0 0 11
GSE74703 RAB3B 5865 4 2 30
GSE74704 RAB3B 5865 2 0 18
TCGA RAB3B 5865 10 18 68

Total number of gains: 48; Total number of losses: 39; Total Number of normals: 401.  

 

Somatic mutations of RAB3B:

 

Generating mutation plots.

 

Highly correlated genes for RAB3B:

 

Showing top 20/341 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAB3BOTX2-AS10.706384303
RAB3BDKK20.700444303
RAB3BZNF4690.672985505
RAB3BADAMTS120.670452605
RAB3BZC3H7B0.662837303
RAB3BCTHRC10.661865404
RAB3BEVA1B0.657782403
RAB3BINHBA0.650417404
RAB3BCAMK40.645821303
RAB3BSPOCD10.644538403
RAB3BPCBP30.644337303
RAB3BGABRG30.644296604
RAB3BCXCR10.639617303
RAB3BFNDC10.637148504
RAB3BNKX2-50.636963404
RAB3BLAYN0.635111605
RAB3BTNFRSF180.633213504
RAB3BRAI140.631656504
RAB3BDACT10.62892403
RAB3BSERPINE10.627465504

For details and further investigation, click here