| Full name: glutathione S-transferase mu 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 2948 | HGNC ID: HGNC:4636 | Ensembl Gene: ENSG00000168765 | OMIM ID: 138333 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTM4 | 2948 | 204149_s_at | 0.0793 | 0.9537 | |
| GSE20347 | GSTM4 | 2948 | 210912_x_at | 0.0479 | 0.8112 | |
| GSE23400 | GSTM4 | 2948 | 210912_x_at | -0.0589 | 0.3479 | |
| GSE26886 | GSTM4 | 2948 | 210912_x_at | -0.3098 | 0.4038 | |
| GSE29001 | GSTM4 | 2948 | 210912_x_at | -0.2773 | 0.3208 | |
| GSE38129 | GSTM4 | 2948 | 210912_x_at | -0.0643 | 0.7354 | |
| GSE45670 | GSTM4 | 2948 | 210912_x_at | -0.3928 | 0.3091 | |
| GSE53622 | GSTM4 | 2948 | 100236 | -0.1852 | 0.4165 | |
| GSE53624 | GSTM4 | 2948 | 100236 | -0.0454 | 0.8212 | |
| GSE63941 | GSTM4 | 2948 | 210912_x_at | -0.0298 | 0.9760 | |
| GSE77861 | GSTM4 | 2948 | 210912_x_at | -0.0857 | 0.7436 | |
| GSE97050 | GSTM4 | 2948 | A_23_P217917 | -0.9281 | 0.1725 | |
| SRP007169 | GSTM4 | 2948 | RNAseq | 1.0361 | 0.1696 | |
| SRP008496 | GSTM4 | 2948 | RNAseq | 0.8237 | 0.1190 | |
| SRP064894 | GSTM4 | 2948 | RNAseq | 0.0087 | 0.9768 | |
| SRP133303 | GSTM4 | 2948 | RNAseq | -0.6433 | 0.0410 | |
| SRP159526 | GSTM4 | 2948 | RNAseq | 1.5473 | 0.0208 | |
| SRP193095 | GSTM4 | 2948 | RNAseq | 0.1024 | 0.7140 | |
| SRP219564 | GSTM4 | 2948 | RNAseq | -0.9927 | 0.1738 | |
| TCGA | GSTM4 | 2948 | RNAseq | -0.0566 | 0.7663 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GSTM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTM4 | 2948 | 0 | 12 | 18 | |
| GSE20123 | GSTM4 | 2948 | 0 | 11 | 19 | |
| GSE43470 | GSTM4 | 2948 | 0 | 9 | 34 | |
| GSE46452 | GSTM4 | 2948 | 2 | 1 | 56 | |
| GSE47630 | GSTM4 | 2948 | 9 | 5 | 26 | |
| GSE54993 | GSTM4 | 2948 | 0 | 1 | 69 | |
| GSE54994 | GSTM4 | 2948 | 7 | 4 | 42 | |
| GSE60625 | GSTM4 | 2948 | 0 | 0 | 11 | |
| GSE74703 | GSTM4 | 2948 | 0 | 7 | 29 | |
| GSE74704 | GSTM4 | 2948 | 0 | 7 | 13 | |
| TCGA | GSTM4 | 2948 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.
Somatic mutations of GSTM4:
Generating mutation plots.
Highly correlated genes for GSTM4:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTM4 | GSTM1 | 0.710871 | 13 | 0 | 13 |
| GSTM4 | GSTM2 | 0.659605 | 13 | 0 | 13 |
| GSTM4 | ZNF775 | 0.637423 | 3 | 0 | 3 |
| GSTM4 | KCNE3 | 0.63683 | 4 | 0 | 4 |
| GSTM4 | TNRC6C | 0.628822 | 3 | 0 | 3 |
| GSTM4 | MRAP2 | 0.597932 | 5 | 0 | 3 |
| GSTM4 | TSPAN7 | 0.579611 | 12 | 0 | 10 |
| GSTM4 | TMEM116 | 0.577683 | 8 | 0 | 6 |
| GSTM4 | IL1RL1 | 0.57532 | 3 | 0 | 3 |
| GSTM4 | TALDO1 | 0.574099 | 7 | 0 | 4 |
| GSTM4 | CYP4F2 | 0.570057 | 11 | 0 | 7 |
| GSTM4 | GSTM3 | 0.566798 | 12 | 0 | 7 |
| GSTM4 | MPP4 | 0.565575 | 3 | 0 | 3 |
| GSTM4 | RFFL | 0.565352 | 3 | 0 | 3 |
| GSTM4 | FECH | 0.563972 | 5 | 0 | 4 |
| GSTM4 | CYP4F3 | 0.558314 | 10 | 0 | 7 |
| GSTM4 | NQO1 | 0.556133 | 7 | 0 | 4 |
| GSTM4 | OTX2-AS1 | 0.556033 | 3 | 0 | 3 |
| GSTM4 | HACL1 | 0.550383 | 3 | 0 | 3 |
| GSTM4 | NFE2L2 | 0.549954 | 5 | 0 | 3 |
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