| Full name: diphthamide biosynthesis 5 | Alias Symbol: CGI-30 | ||
| Type: protein-coding gene | Cytoband: 1p21.2 | ||
| Entrez ID: 51611 | HGNC ID: HGNC:24270 | Ensembl Gene: ENSG00000117543 | OMIM ID: 611075 |
| Drug and gene relationship at DGIdb | |||
Expression of DPH5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPH5 | 51611 | 224196_x_at | 0.0349 | 0.9673 | |
| GSE20347 | DPH5 | 51611 | 219590_x_at | 0.1387 | 0.1815 | |
| GSE23400 | DPH5 | 51611 | 219590_x_at | -0.0133 | 0.7412 | |
| GSE26886 | DPH5 | 51611 | 223671_x_at | -0.1376 | 0.4515 | |
| GSE29001 | DPH5 | 51611 | 219590_x_at | 0.0352 | 0.8416 | |
| GSE38129 | DPH5 | 51611 | 219590_x_at | 0.1019 | 0.2037 | |
| GSE45670 | DPH5 | 51611 | 224196_x_at | -0.0877 | 0.3706 | |
| GSE53622 | DPH5 | 51611 | 67598 | 0.2971 | 0.0001 | |
| GSE53624 | DPH5 | 51611 | 67598 | 0.3407 | 0.0000 | |
| GSE63941 | DPH5 | 51611 | 224196_x_at | 0.3085 | 0.5351 | |
| GSE77861 | DPH5 | 51611 | 223671_x_at | -0.1052 | 0.5654 | |
| GSE97050 | DPH5 | 51611 | A_23_P148821 | -0.0456 | 0.8462 | |
| SRP007169 | DPH5 | 51611 | RNAseq | 0.1378 | 0.7632 | |
| SRP008496 | DPH5 | 51611 | RNAseq | 0.1551 | 0.5393 | |
| SRP064894 | DPH5 | 51611 | RNAseq | 0.0296 | 0.8748 | |
| SRP133303 | DPH5 | 51611 | RNAseq | 0.0300 | 0.6977 | |
| SRP159526 | DPH5 | 51611 | RNAseq | -0.1502 | 0.4752 | |
| SRP193095 | DPH5 | 51611 | RNAseq | -0.2519 | 0.0022 | |
| SRP219564 | DPH5 | 51611 | RNAseq | -0.1987 | 0.5179 | |
| TCGA | DPH5 | 51611 | RNAseq | -0.0171 | 0.7769 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DPH5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPH5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPH5 | 51611 | 0 | 10 | 20 | |
| GSE20123 | DPH5 | 51611 | 0 | 10 | 20 | |
| GSE43470 | DPH5 | 51611 | 2 | 6 | 35 | |
| GSE46452 | DPH5 | 51611 | 1 | 1 | 57 | |
| GSE47630 | DPH5 | 51611 | 9 | 5 | 26 | |
| GSE54993 | DPH5 | 51611 | 0 | 1 | 69 | |
| GSE54994 | DPH5 | 51611 | 6 | 3 | 44 | |
| GSE60625 | DPH5 | 51611 | 0 | 0 | 11 | |
| GSE74703 | DPH5 | 51611 | 1 | 5 | 30 | |
| GSE74704 | DPH5 | 51611 | 0 | 6 | 14 | |
| TCGA | DPH5 | 51611 | 8 | 25 | 63 |
Total number of gains: 27; Total number of losses: 72; Total Number of normals: 389.
Somatic mutations of DPH5:
Generating mutation plots.
Highly correlated genes for DPH5:
Showing top 20/110 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPH5 | TMX3 | 0.80051 | 3 | 0 | 3 |
| DPH5 | CSRP2 | 0.732858 | 3 | 0 | 3 |
| DPH5 | VPS41 | 0.728878 | 3 | 0 | 3 |
| DPH5 | WDR36 | 0.72279 | 3 | 0 | 3 |
| DPH5 | MRPL45 | 0.722388 | 4 | 0 | 3 |
| DPH5 | CRLS1 | 0.706955 | 3 | 0 | 3 |
| DPH5 | HAUS1 | 0.700876 | 3 | 0 | 3 |
| DPH5 | MALT1 | 0.700349 | 3 | 0 | 3 |
| DPH5 | TMED4 | 0.687914 | 3 | 0 | 3 |
| DPH5 | ASCC1 | 0.687234 | 4 | 0 | 4 |
| DPH5 | CYCS | 0.684842 | 3 | 0 | 3 |
| DPH5 | BBS9 | 0.682383 | 4 | 0 | 3 |
| DPH5 | HSPB11 | 0.677352 | 3 | 0 | 3 |
| DPH5 | BIRC2 | 0.674489 | 3 | 0 | 3 |
| DPH5 | CDC14A | 0.662321 | 4 | 0 | 3 |
| DPH5 | PIGK | 0.661594 | 5 | 0 | 4 |
| DPH5 | MIER1 | 0.661468 | 4 | 0 | 3 |
| DPH5 | SLC39A9 | 0.659788 | 3 | 0 | 3 |
| DPH5 | PKN2 | 0.65777 | 3 | 0 | 3 |
| DPH5 | ECI2 | 0.656818 | 3 | 0 | 3 |
For details and further investigation, click here
