SUGP2

 

Full name: SURP and G-patch domain containing 2 Alias Symbol: KIAA0365
Type: protein-coding gene Cytoband: 19p13
Entrez ID: 10147 HGNC ID: HGNC:18641 Ensembl Gene: ENSG00000064607 OMIM ID: 607993
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SUGP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SUGP2 10147 214092_x_at 0.0207 0.9665
GSE20347 SUGP2 10147 213505_s_at 0.1088 0.2664
GSE23400 SUGP2 10147 212001_at 0.1109 0.0607
GSE26886 SUGP2 10147 214092_x_at 0.3686 0.1047
GSE29001 SUGP2 10147 214092_x_at 0.4621 0.0886
GSE38129 SUGP2 10147 214092_x_at 0.2480 0.0213
GSE45670 SUGP2 10147 214092_x_at 0.0199 0.8946
GSE53622 SUGP2 10147 7451 -0.0010 0.9899
GSE53624 SUGP2 10147 7451 0.2105 0.0007
GSE63941 SUGP2 10147 213505_s_at -0.1204 0.6751
GSE77861 SUGP2 10147 213505_s_at 0.2470 0.1287
GSE97050 SUGP2 10147 A_23_P16562 -0.1659 0.4331
SRP007169 SUGP2 10147 RNAseq 0.2812 0.4647
SRP008496 SUGP2 10147 RNAseq 0.3565 0.1868
SRP064894 SUGP2 10147 RNAseq 0.0925 0.5755
SRP133303 SUGP2 10147 RNAseq 0.0267 0.8451
SRP159526 SUGP2 10147 RNAseq 0.1434 0.5130
SRP193095 SUGP2 10147 RNAseq 0.2340 0.0295
SRP219564 SUGP2 10147 RNAseq 0.1136 0.6165

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SUGP2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of SUGP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SUGP2 10147 4 5 21
GSE20123 SUGP2 10147 3 3 24
GSE43470 SUGP2 10147 2 5 36
GSE46452 SUGP2 10147 47 1 11
GSE47630 SUGP2 10147 5 8 27
GSE54993 SUGP2 10147 16 4 50
GSE54994 SUGP2 10147 6 13 34
GSE60625 SUGP2 10147 9 0 2
GSE74703 SUGP2 10147 2 3 31
GSE74704 SUGP2 10147 0 3 17
TCGA SUGP2 10147 16 11 69

Total number of gains: 110; Total number of losses: 56; Total Number of normals: 322.  


 

Somatic mutations of SUGP2:

 

Generating mutation plots.

 

Highly correlated genes for SUGP2:

 

Showing top 20/396 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SUGP2SLC25A290.775577303
SUGP2NDUFA30.775462303
SUGP2ZNF3970.771795303
SUGP2RICTOR0.755615303
SUGP2ANAPC40.751796303
SUGP2MIER20.747324303
SUGP2WBP40.734633303
SUGP2FYN0.726606303
SUGP2SUGP10.720276403
SUGP2TAF150.71849403
SUGP2ZNF7910.716949403
SUGP2N4BP2L20.716247303
SUGP2PRRC2C0.716083303
SUGP2DDX60.715738303
SUGP2RBM390.713166303
SUGP2PAN30.712664303
SUGP2CDC160.712472303
SUGP2ZNF2840.71091303
SUGP2REC80.710824303
SUGP2MIA30.706344303

For details and further investigation, click here